Results 151 to 160 of about 24,824,508 (325)

Pituitary apoplexy : can histopathology, radiological imaging and predisposing factors be used in predicting outcome? [PDF]

open access: yes, 2008
Includes abstract.Includes bibliographical references (leaves 98-112).Pituitary apoplexy is an uncommon, yet potentially fatal illness, usually the result of infarction, hemorrhage or a combination of both in a pituitary tumor.
Semple, Patrick Lyle
core   +1 more source

Geographical alignment of prehospital critical care services with population need for out-of-hospital cardiac arrest patients

open access: yesScandinavian Journal of Trauma, Resuscitation and Emergency Medicine
Background Prehospital critical care is associated with improved outcomes following out-of-hospital cardiac arrest (OHCA), but may not be distributed equitably.
Adam J. Boulton   +11 more
doaj   +1 more source

The immune contexture in human tumours: impact on clinical outcome

open access: yesNature Reviews. Cancer, 2012
W. Fridman   +3 more
semanticscholar   +1 more source

Clinical outcome measures.

open access: yes, 2018
Clinical outcome measures.
Andrew M. Scheidler (5870450)   +4 more
core   +1 more source

Design and analysis strategies for robust microbiome ageing research

open access: yesFEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik   +5 more
wiley   +1 more source

CLINICAL OUTCOMES [PDF]

open access: yesJapanese Journal of Clinical Oncology, 2011
Y. Horikawa   +196 more
openaire   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

open access: yesFEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang   +4 more
wiley   +1 more source

Persistent Cough: Changes in Prevalence, Impact, and Beliefs From 2006–2015 in Italy

open access: yesEuropean Medical Journal, 2019
Background: Persistent cough is one of the most common conditions affecting quality of life. The aim of this study was to assess people’s beliefs regarding the impact of, and changes in the prevalence of, persistent cough in the Italian general ...
Roberto Walter Dal Negro   +3 more
doaj  

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