Results 61 to 70 of about 4,732,881 (277)

A Systematic Review of International Clinical Guidelines for Rehabilitation of People With Neurological Conditions: What Recommendations Are Made for Upper Limb Assessment? [PDF]

, 2019
Conclusions: We present a comprehensive, critical, and original summary of current recommendations. Defining a core set of measures and agreed protocols requires international consensus between experts representing the diverse and multi-disciplinary ...
Alt Murphy, Margit, Burridge, Jane, Buurke, Jaap, Feys, Peter, Hughes, Ann-Marie, Keller, Thierry, Klamroth-Marganska, Verena, Lamers, Ilse, McNicholas, Lauren, Prange, Gerdienke, Tarkka, Ina, Timmermans, Annick   +11 more
core   +5 more sources

The cytoskeletal control of B cell receptor and integrin signaling in normal B cells and chronic lymphocytic leukemia

FEBS Letters, EarlyView.
In lymphoid organs, antigen recognition and B cell receptor signaling rely on integrins and the cytoskeleton. Integrins act as mechanoreceptors, couple B cell receptor activation to cytoskeletal remodeling, and support immune synapse formation as well as antigen extraction.
Abhishek Pethe, Tanja Nicole Hartmann
wiley   +1 more source

Evaluation of the efficacy and safety of sarilumab combination therapy in patients with rheumatoid arthritis with inadequate response to conventional disease-modifying antirheumatic drugs or tumour necrosis factor α inhibitors: systematic literature review and network meta-analyses

RMD Open, 2019
Objective To compare efficacy and safety of subcutaneous sarilumab 200 mg and 150 mg every 2 weeks plus conventional synthetic disease-modifying antirheumatic drugs (+csDMARDs) versus other targeted DMARDs+csDMARDs and placebo+csDMARDs, in inadequate ...
Ernest Choy, Nick Freemantle, Clare Proudfoot, Chieh-I Chen, Laurence Pollissard, Andreas Kuznik, Hubert Van Hoogstraten, Erin Mangan, Paulo Carita, Thi-Minh-Thao Huynh   +9 more
doaj   +1 more source

Gyrification brain abnormalities as predictors of outcome in anorexia nervosa. [PDF]

, 2015
Gyrification brain abnormalities are considered a marker of early deviations from normal developmental trajectories and a putative predictor of poor outcome in psychiatric disorders.
Daniela, Degortes, Favaro, Angela, Renzo, Manara, Santonastaso, Paolo, Tenconi, Elena   +4 more
core   +1 more source

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

FEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro, Marco Cellani, Cristina Scielzo   +2 more
wiley   +1 more source

Impact of preeclampsia on maternal and neonatal health: A retrospective cohort study

Russian Open Medical Journal
Objective — Understanding the relationship between maternal characteristics of patients with preeclampsia (PE) and disease progression, as well as the impact on neonatal and parturient outcomes, is critical to the development of effective interventions ...
Sakine Rahimli Ocakoglu, Zeliha Atak, Burak Akselim, Seniha Gunduz Corabay, Merve Erten Esen   +4 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

FEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez, Juan Carlos Ruiz‐Rodríguez, Ricard Ferrer, Raquel Durá, Antonio Artigas, Iván Bajaña, David Bolado López de Andujar, Irene Cánovas‐Cervera, Adrián Ceccato, Luis Chiscano‐Camón, Elena Climent‐Martinez, Georgia García Fernández, Gemma Goma, Verónica Monforte, Beatriz Quevedo‐Sánchez, Adolf Ruiz‐Sanmartín, Antonio Sierra‐Rivera, Nieves Carbonell Monleón   +17 more
wiley   +1 more source

Review of Clinical Outcome Assessments in Pediatric Attention-Deficit/Hyperactivity Disorder

Neuropsychiatric Disease and Treatment, 2020
Jessica T Markowitz,1 Dorothee Oberdhan,2 Anna Ciesluk,1 Alissa Rams,1 Sharon B Wigal3 1Research Department, Modus Outcomes, Cambridge, MA 02142, USA; 2HEOR and Outcomes Management, Otsuka America Pharmaceutical, Inc, Rockville, MD 20850, USA ...
Markowitz JT, Oberdhan D, Ciesluk A, Rams A, Wigal SB   +4 more
doaj  

Deconstructing the Minimum Clinically Important Difference (MCID)

Orthopedic Research and Reviews, 2022
Janine Molino,1,2 Joseph Harrington,2 Jennifer Racine-Avila,2 Roy Aaron2 1Lifespan Biostatistics Core, Rhode Island Hospital, Providence, RI, USA; 2Department of Orthopedic Surgery, Warren Alpert Medical School of Brown University, Providence, RI ...
Molino J, Harrington J, Racine-Avila J, Aaron R   +3 more
doaj  

Predictive validity of the START for unauthorised leave and substance abuse in a secure mental health setting:a pseudo-prospective cohort study [PDF]

, 2015
Background Risk assessment and management is central to the nursing role in forensic mental health settings. The Short Term Assessment of Risk and Treatability (START) aims to support assessment through identification of risk and protective factors.
Dickens, Geoffrey L., O'Shea, Laura E.
core   +2 more sources