Results 81 to 90 of about 4,732,881 (277)
In the context of recent approvals of amyloid‐directed monoclonal antibodies for the treatment of Alzheimer's disease (AD) by the United States (U.S.) Food and Drug administration (FDA), there has been much public discussion regarding the meaningfulness ...
Teresa Buracchio+2 more
doaj +1 more source
Flexible approaches to eCOA administration in clinical trials: The site perspective
The Critical Path Institute convened the Support Flexible Approaches to PRO Data Collection project as part of the eCOA: Getting Better Together Initiative which was instigated to identify and address common challenges and drive positive change with eCOA
Estelle Haenel+4 more
doaj +1 more source
Qualitative outcome assessment and research on chronic disease management in general practice : highlights from a keynote lecture, EGPRN May 2011, Nice [PDF]
At its 2011 conference in Nice, France, the European General Practice Research Network (EGPRN), considered the issue of Relevant Outcome Measures in General Practice Research into Chronic Diseases.
Griffiths, Frances
core +1 more source
Assessment of Clinical Outcomes in Acute Stroke Trials [PDF]
Background and Purpose —Adequate outcome assessment is crucial to randomized trials. We wished to assess the types of outcomes used in acute stroke trials and the appropriateness of these outcomes and their analyses. Methods —Acute stroke trials from the Cochrane Stroke Group’s ...
Carl Counsell, Lucy Roberts
openaire +3 more sources
Age as a determinant of nutritional status: A cross sectional study [PDF]
Background Undenutrition is known to be prevalent and largely unrecognised in older patients; however, aberrations in indicators of nutritional status may simply reflect effects of age and/or functional disability.
Forster, S., Gariballa, S.
core +4 more sources
Immunohistochemical staining for oestrogen receptor (ER) has been carried out using antibody ER ID5 on 170 women who received first-line tamoxifen treatment for evaluable metastatic breast cancer.
D. Barnes+4 more
semanticscholar +1 more source
Implementing musculoskeletal outcome assessments in clinical practice [PDF]
Summary. Standardized outcome measures allow us to be more objective when measuring the impact of therapy on persons with haemophilia. Many excellent measures have been developed for haemophilia – especially in the health domains of structure and function, and activities; excellent health status/health‐related quality‐of‐life tools have also been ...
openaire +3 more sources
A prospective adaptive utility trial to validate performance of a novel urine exosome gene expression assay to predict high-grade prostate cancer in patients with prostate-specific antigen 2-10ng/ml at initial biopsy [PDF]
BACKGROUND: Discriminating indolent from clinically significant prostate cancer (PCa) in the initial biopsy setting remains an important issue. Prospectively evaluated diagnostic assays are necessary to ensure efficacy and clinical adoption.
Andriole, Gerry+12 more
core +1 more source
Quality of life in patients with intermittent claudication [PDF]
© 2017, The Author(s). Background: Intermittent claudication (IC) is a common condition that causes pain in the lower limbs when walking and has been shown to severely impact the quality of life (QoL) of patients.
Broadbent, E.+4 more
core +1 more source