Results 221 to 230 of about 1,695,081 (360)

Integrated Clinical Pathway of diabetic retinopaty Screening in the North West Tuscany Local Health Authority

F. Pancani
openalex   +1 more source

PARP inhibitors induce a senescence phenotype in non‐small cell lung carcinoma cell lines

FEBS Open Bio, EarlyView.
Talazoparib is the most potent inducer of senescence among different PARP1 inhibitors in human NSCLC cells. In the absence of PARP, no senescence phenotype was observed, demonstrating that PARP1 is necessary for the induction of senescence by this inhibitor.
Camille Huart, Manon Van den Abbeel, Christoph Schifflers, Karim Bouhjar, Andrea Scarmelotto, Alexis Khelfi, Anne‐Catherine Wera, Carine Michiels   +7 more
wiley   +1 more source

Erythropoietin modulates hepatic inflammation, glucose homeostasis, and soluble epoxide hydrolase and epoxides in high‐fat diet‐induced obese mice

FEBS Open Bio, EarlyView.
Erythropoietin administration suppresses hepatic soluble epoxide hydrolase (sEH) expression, leading to increased CYP‐derived epoxides. This is associated with a shift in hepatic macrophage polarization characterized by reduced M1 markers and increased M2 markers, along with reduced hepatic inflammation, suppressed hepatic lipogenesis, and attenuated ...
Takeshi Goda, Satoru Sugimoto, Chiharu Cho, Madoka Konishi, Nozomi Inoue, Satoshi Miyagaki, Yasuhiro Kawabe, Takuro Okamura, Masahide Hamaguchi, Hisakazu Nakajima, Michiaki Fukui, Masakazu Shinohara, Tomoko Iehara   +12 more
wiley   +1 more source

Refining the Clinical Pathway for Nasotracheal Intubation: An Updated Decision Making Algorithm. [PDF]

J Clin Med
Desilva M, Maan R, Helwany M, Shah SS.
europepmc   +1 more source

Polymorphisms of mismatch repair pathway genes predict clinical outcomes in acute myeloid leukemia patients

Amin Zhang, Wancheng Liu, Can Can, Xiaodong Guo, Hexiao Jia, Yihong Wei, Hanyang Wu, Chunyan Ji, Daoxin Ma   +8 more
openalex   +1 more source

Immunohistochemical profiling of caspase signaling pathways predicts clinical response to chemotherapy in primary nodal diffuse large B-cell lymphomas [PDF]

, 2004
Jettie J.F. Muris, Saskia A.G.M. Cillessen, Wim Vos, Inge S. van Houdt, J. Alain Kummer, J. Han van Krieken, Natasha Jiwa, Patty M. Jansen, Hanneke C. Kluin‐Nelemans, Gert J. Ossenkoppele, Chad M. Gundy, Chris J.L.M. Meijer, Joost J. Oudejans   +12 more
openalex   +1 more source

Identification of functional murine mitochondrial formyl peptides and their effects on myeloid‐derived suppressor cell generation

FEBS Open Bio, EarlyView.
We first identified functional murine mitochondrial N‐formyl peptides (MT‐FPs) and investigated their effects on the in vitro myeloid‐derived suppressor cell (MDSC) generation from bone marrow cells. We demonstrated that MT‐FPs acted directly on bone marrow cells to promote MDSC generation and modulated the polymorphonuclear (PMN)‐MDSC/monocyte (M ...
Miyako Ozawa, Saori Kagoshima, Akira Yamada   +2 more
wiley   +1 more source

Clinical Impact of Implementing a Specific Clinical Pathway for the Management of Clostridioides difficile Infection. [PDF]

Infect Dis Ther
Rodríguez-Fernández M, Herrero R, González-De-La-Aleja P, Valverde-Fredet MD, Ventero MP, Trigo-Rodríguez M, Giner L, Aller-García AI, Pinargote-Celorio H, Espíndola-Gómez R, Parra M, Martínez Pérez-Crespo P, Ramos-Rincón JM, Fernández-Pevida A, Lanz-García J, León E, Valiente-De-Santis L, Corzo JE, Rodríguez JC, Merino E, Merchante N.   +20 more
europepmc   +1 more source

Clinical Impact of Upfront Apalutamide Dose Reduction in Androgen Pathway Modulation–Naïve Metastatic Prostate Cancer [PDF]

Kotona Miyauchi, Takuma Narita, Shun Morishita, Naoki Fujita, Daiki Kikuchi, Noriyuki Abe, Miyu Ohtani, Shin Kobayashi, Naoki Wada, Shingo Hatakeyama, Kazuyuki Numakura   +10 more
openalex   +1 more source

Exon 7 splicing of ERα predicts poor prognosis and increases phenotypic heterogeneity in luminal a subtype breast cancer

FEBS Open Bio, EarlyView.
ERα splice variant ERα∆7 lacks the C‐terminus, and its expression may change phenotypes of breast cancers. Our results showed that ERα∆7 is found in the luminal A subtype, and elevated ERα∆7 levels are linked to improved cell survival with lower proliferation and migration.
Long Wai Tsui, Taobo Hu, Thomson Christian Husein, Wai Hei Shek, Bingrong Chen, Depeng Wang, Shu Wang, Weichuan Yu, Xiaodan Fan, Mengping Long, Toyotaka Ishibashi   +10 more
wiley   +1 more source