Results 251 to 260 of about 1,695,081 (360)

Six Sigma and Statistical Process Control in Clinical Pathway Management: An Evaluation Using Coefficient of Variation, Control Charts, and Process Performance Index. [PDF]

Risk Manag Healthc Policy
Li KC, Zeng W, Su K, Li G.
europepmc   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Co-designing a new clinical pathway to support families with children identified as having early-stage type 1 diabetes in Western Australia. [PDF]

Diabetologia
Black SKP, Tully A, Davis EA, Roberts A, Binkowski S, Cromb L, Taplin C, Mellor BR, Bebbington K, Haynes A.   +9 more
europepmc   +1 more source

Blood‐based proteomic profiling reveals context‐dependent changes in BCL2‐associated signaling during taxane therapy in breast cancer patients

FEBS Open Bio, EarlyView.
Chemotherapy side effects significantly impact cancer survivors' quality of life. Using protein levels in blood samples from breast cancer patients before and after 12 weeks of taxane treatment, we detected treatment‐dependent changes in calcium signaling and aging pathways associated with cancer recurrence.
Saira Munshani, Eiman Y. Ibrahim, Rozalyn L. Rodwin, Leah M. Ferrucci, Kim Blenman, Maryam Lustberg, Barbara E. Ehrlich   +6 more
wiley   +1 more source

Nursing intervention of oral mucositis after chemotherapy in patients with acute myeloid leukemia

Huli yanjiu, 2020
LUO Yan, ZHANG Yueying
doaj  

Exploration of clinical pathway practice for optimization of DRG costing results based on resource consumption. [PDF]

BMC Med Inform Decis Mak
Wu SQ, Wang XC, Boyd AD, Feng D, Zhong M, Nie D.   +5 more
europepmc   +1 more source

CLINICAL OUTCOMES OF IMPLEMENTING CONGESTIVE HEART FAILURE PATHWAY IN PATIENT HOSPITALIZED WITH ACUTELY DECOMPENSATED HEART FAILURE [PDF]

Shraddha Bhattarai, MUHAMMAD ASLAM KHAN, Asna Aafreen, John Pamula   +3 more
openalex   +1 more source

Long‐term hippocampal alterations and cognitive impairment in a murine model of surgical sepsis

FEBS Open Bio, EarlyView.
Using a mouse model of surgical sepsis, we tested long‐term memory and analyzed the transcriptome of single cells isolated from the hippocampus. Survivor mice showed worse memory, loss of certain brain cell subpopulations, and abnormal immune cell activity—suggesting that post‐sepsis brain alterations may be linked to cognitive deficits.
Dong Seong Cho, Rebecca Schmitt, Aneesha Dasgupta, Alexandra Ducharme, Jason Doles   +4 more
wiley   +1 more source

Clinical and economic impacts of a clinical pathway-based single disease payment policy on hysterectomy for uterine fibroids: a decade-long interrupted time series analysis. [PDF]

Front Public Health
Zheng H, Li Z, Lin H, Yi H, Zheng X.
europepmc   +1 more source

Gene clusters-based pathway enrichment analysis identifies four pan-cancer subtypes with distinct molecular and clinical features [PDF]

Mengli Xu, Hongjing Ai, Danni Wang, Xiaosheng Wang   +3 more
openalex   +1 more source