Results 11 to 20 of about 951,333 (183)

Neuroinflammatory targets and treatments for epilepsy validated in experimental models [PDF]

, 2017
A large body of evidence that has accumulated over the past decade strongly supports the role of inflammation in the pathophysiology of human epilepsy.
Abraham, Abs, Akin, Aronica, Aronica, Ashraf, Auvin, Bar-Klein, Basler, Bhala, Bozzi, Cacheaux, Cerri, Citraro, Dianzani, Diaz-Hernandez, Dityatev, Drion, Engel, Fabene, Friedman, Fu, Fukasawa, Galanopoulou, Ganesh, Gorter, Groettrup, Groettrup, He, Heinemann, Henshall, Holtman, Huang, Iori, Iyer, Jiang, Jimenez-Pacheco, Jimenez-Pacheco, Jung, Kim, Kim, Kwon, Liang, Liepe, Louboutin, Louboutin, Marchi, Maroso, Maroso, Marusich, McRae, Mishto, Mishto, Mishto, Mishto, Mishto, Noe, Nomura, O'Neill, Podojil, Polascheck, Pollock, Prabowo, Quan, Ravizza, Ravizza, Rojas, Rojas, Rojas, Rojas, Roseti, Roseti, Ruden, Sadowski, Scheppingen, Scheppingen, Serrano, Takenouchi, Thalhammer, Varvel, Vezzani, Vezzani, Vezzani, Vezzani, Vezzani, Vliet, Vliet, Volonte, Vries, Wei, Zanker, Zeng, Zhang   +92 more
core   +13 more sources

Clinical Pathways to Ethically Substantive Autonomy [PDF]

, 2013
There is no shortage of support for the idea that ethics should be incorporated into the academic and professional curriculum. There is a difference, however, between, on the one hand, teaching professionals about ethics, and, on the other, demanding ...
Drake, Philip, Toddington, Stuart
core   +2 more sources

Building Data-Driven Pathways From Routinely Collected Hospital Data:A Case Study on Prostate Cancer [PDF]

, 2015
Background: Routinely collected data in hospitals is complex, typically heterogeneous, and scattered across multiple Hospital Information Systems (HIS).
Adriansyah, A, Cios, KJ, Holmström, Benny, Lang, M, Luc, Kd, Mans, R, Mans, R, Pearson, SD, Safran, C   +8 more
core   +2 more sources

Computerization of workflows, guidelines and care pathways: a review of implementation challenges for process-oriented health information systems [PDF]

, 2011
There is a need to integrate the various theoretical frameworks and formalisms for modeling clinical guidelines, workflows, and pathways, in order to move beyond providing support for individual clinical decisions and toward the provision of process ...
Gooch, P., Roudsari, A.
core   +1 more source

Care pathways models and clinical outcomes in disorders of consciousness [PDF]

, 2017
Objective: Patients with Disorders of consciousness, are persons with extremely low functioning levels and represent a challenge for health care systems due to their high needs of facilitating environmental factors.
Antoniono, Elena, Arcuri, Francesco, Avesani, Renato, Bramanti, Placido, Buffoni, Mara, Cardinale, Viviana, Corallo, Francesco, Corsico, Paolo, D'ippolito, Mariagrazia, De Nigris, Fulvio, De Torres, Laura, Dessi, Barbara, Dolce, Giuliano, Estraneo, Anna, Feller, Sandro, Ferro, Salvatore, Fogar, Paolo, Formisano, Rita, Lamberti, Gianfranco, Lanzillotti, Crocifissa, Leonardi, Matilde, Martinuzzi, Andrea, Mazza, Luigi, Morganti, Laura, Navarro, Jorge, Pessina, Adriano, Piperno, Roberto, Salvi, Luca, Sattin, Davide, Scarponi, Federico, Vassallo, Claudio, Zampolini, Mauro, Zavatta, Elena   +32 more
core   +1 more source

Identification of molecular markers of delayed graft function based on the regulation of biological ageing [PDF]

, 2016
Introduction: Delayed graft function is a prevalent clinical problem in renal transplantation for which there is no objective system to predict occurrence in advance.
Aitken, Emma, Clancy, Marc, Gingell-Littlejohn, Marc, Kerschbaum, Julia, Kingsmore, David B., Koppelstaetter, Christian, Königsrainer, Alfred, Leierer, Johannes, Little, Ann-Margaret, Maglione, Manuel, McConnachie, Alex, McGuinness, Dagmara, Mohammed, Suhaib, Nadalin, Silvio, Schneeberger, Stefan, Shapter, Olivier, Shiels, Paul G., Stevenson, Karen S., Wagner, Sylvia, Whalen, Henry   +19 more
core   +8 more sources

MTOR cross-talk in cancer and potential for combination therapy [PDF]

, 2018
The mammalian Target of Rapamycin (mTOR) pathway plays an essential role in sensing and integrating a variety of exogenous cues to regulate cellular growth and metabolism, in both physiological and pathological conditions.
Bazzichetto, C., Bria, E., Ciuffreda, L., Cognetti, F., Conciatori, F., Falcone, I., Milella, M, Pilotto, S.   +7 more
core   +6 more sources

An evaluation of DNA-damage response and cell-cycle pathways for breast cancer classification [PDF]

, 2014
Accurate subtyping or classification of breast cancer is important for ensuring proper treatment of patients and also for understanding the molecular mechanisms driving this disease.
Fard, Atefeh Taherian, Ragan, Mark A., Srihari, Sriganesh   +2 more
core   +5 more sources

Cancer Clinical Trials Optimization and Pharmacogenomics [PDF]

, 2012
A critical overview of recent clinical trials in cancer is presented focused on signaling pathways blockers or inhibitors with a view to developing successful clinical trials employing personalized cancer therapies.
I. C. Baianu
core   +2 more sources

Updated management of malignant biliary tract tumors: an illustrative review [PDF]

, 2016
The management of malignant biliary tumors (MBTs) is complex and requires a multidisciplinary approach. Guidelines and methods of staging for biliary tumors have recently been released by main international societies, altering the clinical and radiologic
Cannavale, Alessandro, Catalano, Carlo, Fanelli, Fabrizio, Fiocca, Fausto, Gazzetti, Marianna, Maher, Ben, Santoni, Mariangela   +6 more
core   +1 more source