Results 151 to 160 of about 914,658 (345)

Bipolar Disorder in Pharmacy Practice: Clinical Foundations, Pharmacologic Stewardship, and the Pharmacist's Expanding Role

, 1991
David Gettman
openalex   +1 more source

The Aging Blood: Cellular Origins, Circulating Drivers, and Therapeutic Potential

Aging and Cancer, EarlyView.
As a conduit linking all organs, the blood system both reflects and actively drives systemic aging. This review highlights how circulating pro‐aging and antiaging factors and age‐associated hematopoietic stem cell dysfunction contribute to immunosenescence and multi‐organ decline, positioning the hematopoietic system as a target for aging intervention.
Hanqing He, Jianwei Wang
wiley   +1 more source

Molecular targets of Chinese herbs: a clinical study of hepatoma based on network pharmacology [PDF]

, 2016
Li Gao, Xiaodong Wang, Yangyang Niu, Dandan Duan, Xue Yang, Jian Hao, Cui-Hong Zhu, Dan Chen, Kexin Wang, Xuemei Qin, Xiong-Zhi Wu   +10 more
openalex   +1 more source

Natural Products as Geroprotective Modulators in Diabetic Nephropathy: A Mechanistic Framework Integrating Aging Hallmarks and the AMPK–SIRT1–Nrf2 Axis

Aging and Cancer, EarlyView.
Natural products target the aging kidney in diabetic nephropathy by restoring the AMPK–SIRT1–Nrf2 axis, reducing oxidative stress, inflammation, fibrosis, and cellular senescence while enhancing mitochondrial biogenesis and antioxidant defenses.
Sherif Hamidu, Latif Adams, Eunice Ampem‐Danso, Justice Kumi, Abigail Aning, Fatima Hamidu, Mustapha Abdul Mumin Mohammed, Ayuba Nii Darku Ankrah, Seth Kwabena Amponsah   +8 more
wiley   +1 more source

High prevalence of medication errors in a secondary‐level Lithuanian hospital: A prospective cross‐sectional observational study

Pharmacology Research & Perspectives
As the population continues to age, the occurrence of chronic illnesses and comorbidities that often necessitate the use of polypharmacy has been on the rise. Polypharmacy, among other factors that tend to coincide with chronic diseases, such as obesity,
J. Butauskaite, A. Zumbakyte, L. Aukstikalne, J. Pancere, S. Zukaitiene, E. Karinauske   +5 more
doaj   +1 more source

Recent developments in the clinical pharmacology of rolapitant: subanalyses in specific populations

, 2017
Bernardo L. Rapoport, Matti Aapro, Martin Chasen, Karin Jordan, Rudolph M. Navari, Ian D. Schnadig, Lee S. Schwartzberg   +6 more
openalex   +2 more sources

Vigabatrin (Sabril) for the Treatment of Refractory Complex Focal Seizures in Adults: Pharmacologic and Clinical Considerations [PDF]

, 2023
Taylor Gatson, Orlandria A Freemont, Rachel L. Coleman, Stewart J Lockett, Noah J Spillers, Shahab Ahmadzadeh, Omar Viswanath, Giustino Varrassi, Sahar Shekoohi, Alan D. Kaye   +9 more
openalex   +1 more source

Systemic T Cell Receptor Profiling Reveals Adaptive Immune Activation and Potential Immune Signatures of Diagnosis and Brain Atrophy in Epilepsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy is increasingly associated with immune dysregulation and inflammation. The T cell receptor (TCR), a key mediator of adaptive immunity, shows repertoire alterations in various immune‐mediated diseases. The unique TCR sequence serves as a molecular barcode for T cells, and clonal expansion accompanied by reduced overall TCR ...
Yong‐Won Shin, Sang Bin Hong, Yong Woo Shin, Inpyeong Hwang, Jaeseong Oh, Jihyeon Choi, Narae Kim, Jangsup Moon, Keun‐Hwa Jung, Kyung‐Il Park, Ki‐Young Jung, Kon Chu, Sang Kun Lee   +12 more
wiley   +1 more source

Analysis of pharmacological action and clinical application of DaXueTeng based on its anti-inflammatory action

, 2018
Lihui Zhang, Miaomiao Lin, Ying Che, Xuesong Wu, Lijing Cai, Meishan Li, Guo-wei Zhan   +6 more
openalex   +2 more sources

Systematic analysis of the experimental and clinical pharmacology of nicotinamide and prospects for the treatment of atherosclerosis

, 2023
О. А. Громова, I. Yu. Torshin
openalex   +2 more sources