An Iterative, User-Centered Design of a Clinical Decision Support System for Critical Care Assessments: Co-Design Sessions with ICU Clinical Providers [PDF]
arXivThis study reports the findings of qualitative interview sessions conducted with ICU clinicians for the co-design of a system user interface of an artificial intelligence (AI)-driven clinical decision support (CDS) system. This system integrates medical record data with wearable sensor, video, and environmental data into a real-time dynamic model that ...
arxiv
Integration of Pharmacology into a Dental School’s Problem Based Learning Curriculum [PDF]
, 2010 poster abstractThe purpose of this study is to determine student perceptions of the methods used to teach pharmacology content via Problem Based Learning (PBL) cases with respect to student: comprehension application of pharmacology content, confidence ...
Garetto, L.P. +2 more
core
Advanced Biology, Volume 9, Issue 3, March 2025.Yi‐Fei‐Jie‐Du‐Tang (YFJDT), a traditional Chinese medicine, has shown potential in lung cancer treatment by targeting key pathways. This study explores the mechanisms of YFJDT using bioinformatics, xenograft models, and A549 cells, demonstrating that YFJDT downregulates HIF1A, promotes ferroptosis, and inhibits epithelial‐mesenchymal transition (EMT ...
Shanshan Wang +6 more
wiley +1 more source
Book Review: Animal and Clinical Pharmacologic Techniques in Drug Evaluation [PDF]
, 1969 Randy Schneider
openalex +1 more source
Large Language Models in Drug Discovery and Development: From Disease Mechanisms to Clinical Trials [PDF]
arXivThe integration of Large Language Models (LLMs) into the drug discovery and development field marks a significant paradigm shift, offering novel methodologies for understanding disease mechanisms, facilitating drug discovery, and optimizing clinical trial processes.
arxiv
β‐Catenin/c‐Myc Axis Modulates Autophagy Response to Different Ammonia Concentrations
Advanced Biology, Volume 9, Issue 3, March 2025.Ammonia, detoxified by the liver into urea and glutamine, impacts autophagy differently at varying levels. Low ammonia activates autophagy via c‐Myc and β‐catenin, while high levels suppress it. Using Huh7 cells and Spf‐ash mice, c‐Myc's role in cytoprotective autophagy is revealed, offering insights into hyperammonemia and potential therapeutic ...
S. Sergio +11 more
wiley +1 more source
Why clinical pharmacologists are needed?
Medwave, 2012 Drugs are one of the most widely used by doctors. The development of these as well as the impact that their; use only on benefits, risks or costs have determined the need for specialists in the area.
Andrea Giménez
doaj +1 more source
A look inside the association codeine-paracetamol: clinical pharmacology supports analgesic efficacy [PDF]
, 2015 Acute and chronic pain often requires a multimodal approach. Combination therapy reduces the number of individual daily administrations and improves patient's compliance with the prescribed analgesic treatment. Despite the association codeine/paracetamol
COLUZZI, FLAMINIA, MATTIA, Consalvo
core
Current and Future Cornea Chip Models for Advancing Ophthalmic Research and Therapeutics
Advanced Biology, EarlyView.This review analyzes cornea chip technology as an innovative solution to corneal blindness and tissue scarcity. The examination encompasses recent developments in biomaterial design and fabrication methods replicating corneal architecture, highlighting applications in drug screening and disease modeling while addressing key challenges in mimicking ...
Minju Kim +3 more
wiley +1 more source