Results 291 to 300 of about 11,531,725 (348)
Some of the next articles are maybe not open access.
An update on the clinical pharmacology of miltefosine in the treatment of leishmaniasis.
International Journal of Antimicrobial Agents, 2021Miltefosine is an alkylphosphocholine agent with a broad spectrum of antiparasitic properties. For over two decades now, miltefosine remains the first and only oral drug licensed and used in treatment of the neglected tropical disease leishmaniasis.
Semra Palić, J. Beijnen, T. Dorlo
semanticscholar +1 more source
Journal of clinical pharmacology, 2000
The public press is laden with articles describing serious errors in medical care and treatment that are associated with increased morbidity and mortality.
semanticscholar +1 more source
The public press is laden with articles describing serious errors in medical care and treatment that are associated with increased morbidity and mortality.
semanticscholar +1 more source
Chinese Journal of Natural Medicines, 2021
Traditional Chinese medicine (TCM) is a precious treasure of the Chinese nation and has unique advantages in the prevention and treatment of diseases. The holistic view of TCM coincides with the new generation of medical research paradigm characterized ...
Xin Wang +3 more
semanticscholar +1 more source
Traditional Chinese medicine (TCM) is a precious treasure of the Chinese nation and has unique advantages in the prevention and treatment of diseases. The holistic view of TCM coincides with the new generation of medical research paradigm characterized ...
Xin Wang +3 more
semanticscholar +1 more source
Expert Review of Clinical Pharmacology, 2020
Introduction Methylphenidate remains a first-line medication for treating ADHD in children and adults. However, its behavioral pharmacological similarities to methamphetamine and cocaine have historically created concern for its potential as a drug of ...
Thomas P. Shellenberg +3 more
semanticscholar +1 more source
Introduction Methylphenidate remains a first-line medication for treating ADHD in children and adults. However, its behavioral pharmacological similarities to methamphetamine and cocaine have historically created concern for its potential as a drug of ...
Thomas P. Shellenberg +3 more
semanticscholar +1 more source
Geriatric Clinical Pharmacology
Cardiology Clinics, 1986Age-related physiologic changes may significantly alter drug disposition and dynamics in the elderly. This is especially important for cardiovascular drugs, because they are used with such high frequency in the geriatric population. Alterations in the pharmacokinetics and pharmacodynamics of several drugs used to treat cardiovascular disease have been ...
M L, Rocci, P H, Vlasses, W B, Abrams
openaire +2 more sources
An update on the clinical pharmacology of kratom: uses, abuse potential, and future considerations
Expert Review of Clinical PharmacologyIntroduction Kratom (Mitragyna speciosa) has generated substantial clinical and scientific interest as a complex natural product. Its predominant alkaloid mitragynine and several stereoisomers have been studied for activity in opioid, adrenergic, and ...
Christopher R McCurdy +6 more
semanticscholar +1 more source
JAMA: The Journal of the American Medical Association, 1989
The issue of what drug effects to measure, surrogate end points, has been emphasized by two recent clinical trials. Several recent studies have given us new information about why different people react so differently to the same dose of the same medicine.
openaire +5 more sources
The issue of what drug effects to measure, surrogate end points, has been emphasized by two recent clinical trials. Several recent studies have given us new information about why different people react so differently to the same dose of the same medicine.
openaire +5 more sources
Expert Opinion on Drug Metabolism & Toxicology, 2019
Introduction: Triantennary N-acetyl galactosamine (GalNAc3) – conjugated antisense oligonucleotides (ASOs) have demonstrated improved hepatocyte uptake and pharmacologic activity over their parent unconjugated ASOs in animals and humans.
Yanfeng Wang, R. Yu, S. Henry, R. Geary
semanticscholar +1 more source
Introduction: Triantennary N-acetyl galactosamine (GalNAc3) – conjugated antisense oligonucleotides (ASOs) have demonstrated improved hepatocyte uptake and pharmacologic activity over their parent unconjugated ASOs in animals and humans.
Yanfeng Wang, R. Yu, S. Henry, R. Geary
semanticscholar +1 more source
Emerging Applications of Metabolomics in Clinical Pharmacology
Clinical pharmacology and therapy, 2019Metabolic disturbances have been associated with many human diseases, including cancer, diabetes, and cardiovascular disease. Metabolomics, a rapidly growing member of the –omics family, investigates cellular metabolism by quantifying metabolites on a ...
Huanhuan Pang, Wei Jia, Zeping Hu
semanticscholar +1 more source
Clinical Pharmacology of Inodilators
Journal of Cardiovascular Pharmacology, 1989Recent advances in our knowledge of heart failure have shown that both a central and a peripheral factor are involved in this syndrome. Therefore, the ideal drug should combine the properties of a positive inotropic agent with those of a peripheral vasodilator; many drugs recently introduced into clinical practice have been shown to present both of ...
DEI CAS, Livio +2 more
openaire +3 more sources