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The chemistry, pharmacology and clinical pharmacology of diflunisal
Current Medical Research and Opinion, 1978Studies are reviewed on diflunisal, a new analgesic agent with an improved therapeutic index, compared with acetylsalicylic acid, in animals and humans. Pharmacokinetic data indicate that a twice-daily dosage regimen of diflunisal is adequate for therapeutic purposes.
V. J. Cirillo +2 more
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Clinical Pharmacology of Nicotine
Annual Review of Medicine, 1986Nicotine is the primary reason why people consume tobacco products and it may contribute to causation of tobacco-related diseases. This chapter reviews the human pharmacology of nicotine, the evidence for a role of nicotine in human disease, and the use of nicotine (gum) as a therapeutic agent in smoking cessation therapy.
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The clinical pharmacology of vasoconstrictors
Clinical Pharmacology & Therapeutics, 1966Vasoconstrictors are mainly used in acute hypotensive states, and they often succeed in bringing about at least a temporary increase in arterial pressure. Pressure is easy to measure, whereas tissue perfusion is not; but it is the latter that is the important variable, and a rise in pressure does not necessarily imply an improved circulation.
A. C. Dornhorst, R. L. Hodge
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Clinical pharmacology in Australia
Clinical Pharmacology & Therapeutics, 1974In Australia, clinical pharmacology is a small but developing discipline useful for the generation of data concerning the efficacy and safety of new therapeutic substances. While most clinical pharmacology is carried on as an adiunct to the interests of a specialist in some branch of internal medicine, there are now, in Australia, four units titled ...
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Clinical pharmacology – the basics
Surgery (Oxford), 2009Abstract Clinical pharmacology is the study of pharmacodynamics and pharmacokinetics in humans. The relationship between dose, concentration and pharmacodynamic response may be explored using biomarkers for both desired and undesired effects of drugs.
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Clinical Pharmacology of HFA134a
Journal of Aerosol Medicine, 1995The safety, tolerability and pharmacokinetics of the chlorine-free propellant HFA134a were assessed in healthy subjects after single and repeat doses. Absorption and disposition were investigated in healthy subjects and severe chronic obstructive pulmonary disease (COPD) patients using labelled HFA134a.
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Radiotheranostics in oncology: Making precision medicine possible
Ca-A Cancer Journal for Clinicians, 2023Eric O Aboagye
exaly