Results 71 to 80 of about 471,172 (312)

Developing evidence‐based, cost‐effective P4 cancer medicine for driving innovation in prevention, therapeutics, patient care and reducing healthcare inequalities

Molecular Oncology, EarlyView.
The cancer problem is increasing globally with projections up to the year 2050 showing unfavourable outcomes in terms of incidence and cancer‐related deaths. The main challenges are prevention, improved therapeutics resulting in increased cure rates and enhanced health‐related quality of life.
Ulrik Ringborg, Joachim von Braun, Julio Celis, Anton Berns, Michael Baumann, Tit Albreht, Nancy Abou‐Zeid, Vanderlei Bagnato, Christian Brandts, Chien‐Jen Chen, Massimiliano di Pietro, Manjit Dosanjh, Thomas Dubois, Alexander Eggermont, Angelika Eggert, Ingemar Ernberg, Sara Faithfull, Johannes Förner, Stefan Fröhling, Manuel Heitor, Leroy Hood, Wei Jiang, Bengt Jönsson, Ravi Kannan, Maria Leptin, Su Li, Peter Lindgren, Douglas Lowy, Jun Ma, Alex Markham, Péter Nagy, Simon Oberst, M. Iqbal Parker, Danielle Rodin, Kevin Ryan, Joachim Schüz, Richard Sullivan, Josep Tabernero, Peter Turkson, Oliver Várhelyi, Harold Varmus, Chijie Wang, Elisabete Weiderpass, Nils Wilking   +43 more
wiley   +1 more source

Investigating the organisational factors associated with variation in clinical productivity in community pharmacies: a mixed-methods study

Health Services and Delivery Research, 2017
Background: Community pharmacies play a key role in health-care systems, dispensing prescriptions and providing medicine-related services. Service provision varies across community pharmacy organisations and may depend on organisational characteristics ...
Sally Jacobs, Fay Bradley, Rebecca Elvey, Tom Fegan, Devina Halsall, Mark Hann, Karen Hassell, Andrew Wagner, Ellen Schafheutle   +8 more
doaj   +1 more source

Strengthening the Free Healthcare Initiative through a pharmacy and supply chain intervention: Partners in Health's experience in rural Sierra Leone

The Lancet Global Health, 2017
Background: To improve high maternal and under-5 mortality—among the worst globally—Sierra Leone's Ministry of Health and Sanitation (MOHS) enacted the Free Healthcare Initiative in 2010.
Sheriff L Bangura, BPharm, Katrina Hann, MA, Ameet Salvi, BSc, Rebecca Kahn, BA, Kerry L Dierberg, MD, Joseph Gassimu, BSc, Alpha Kabbah, BPharm, Regan H Marsh, MD   +7 more
doaj   +1 more source

Study protocol: The Adherence and Intensification of Medications (AIM) study - a cluster randomized controlled effectiveness study [PDF]

, 2010
Background Many patients with diabetes have poor blood pressure (BP) control. Pharmacological therapy is the cornerstone of effective BP treatment, yet there are high rates both of poor medication adherence and failure to intensify medications ...
Bosworth, Hayden B, Heisler, Michele M., Hofer, Timothy P., Hogan, Mary M., Kerr, Eve A., Klamerus, Mandi L., Schmittdiel, Julie, Selby, Joe V., Tremblay, Adam   +8 more
core   +5 more sources

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Origins and history of global and Polish clinical pharmacy

Family Medicine & Primary Care Review
The history of global clinical pharmacy can be traced back to the second half of the 20th century. The initiators of the first efforts to disseminate the practice of clinical pharmacists were American pharmacists and American research centers.
Arkadiusz Adamiszak, Sylwia Adamiszak
doaj   +1 more source

Indole bearing thiadiazole analogs: synthesis, β-glucuronidase inhibition and molecular docking study

BMC Chemistry, 2019
Background Indole based thiadiazole derivatives (1–22) have synthesized, characterized by NMR and HREI-MS and evaluated for β-Glucuronidase inhibition. All compounds showed outstanding β-glucuronidase activity with IC50 values ranging between 0.5 ± 0.08 ...
Noor Barak Almandil, Muhammad Taha, Mohammed Gollapalli, Fazal Rahim, Mohamed Ibrahim, Ashik Mosaddik, El Hassane Anouar   +6 more
doaj   +1 more source

Patient safety in health care professional educational curricula: examining the learning experience [PDF]

, 2009
This study has investigated the formal and informal ways pre-registration students from four healthcare professions learn about patient safety in order to become safe practitioners.
Dawson, Pam, Pearson, Pauline, Steven, Alison   +2 more
core  

Integration of HIV Care with Primary Health Care Services: Effect on Patient Satisfaction and Stigma in Rural Kenya. [PDF]

, 2013
HIV departments within Kenyan health facilities are usually better staffed and equipped than departments offering non-HIV services. Integration of HIV services into primary care may address this issue of skewed resource allocation. Between 2008 and 2010,
Adero, Walter, Bukusi, Elizabeth A, Cohen, Craig R, Kioko, Jackson, Leslie, Hannah H, Lewis-Kulzer, Jayne, Odeny, Thomas A, Penner, Jeremy, Shade, Starley B   +8 more
core   +2 more sources

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source