Results 21 to 30 of about 2,133,135 (297)
Objectives To enhance the research value and capability of its primary care database, the Clinical Practice Research Datalink (CPRD) has collaborated with Public Health England (PHE)’s National Cancer Registration and Analysis Service to facilitate ...
Sophia Amjad+4 more
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Pharmacogenetics in Clinical Practice [PDF]
Pharmacogenetics is a discipline that investigates how genetic variation relates to the drug efficacy and safety. The goal of pharmacogenetics is a personalized treatment, where according to genotype we would be able to prescribe the most effective drug at the most appropriate dose for an individual patient.
Hana Bakhouche, Ondřej Slanař
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Background Improving the speed of systematic review (SR) development is key to supporting evidence-based medicine. Machine learning tools which semi-automate citation screening might improve efficiency.
Amy Y. Tsou+3 more
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Background Thrombotic thrombocytopenic purpura (TTP) is a rare, life‐threatening thrombotic microangiopathy (TMA), characterized by ADAMTS‐13 activity
Alicia White+4 more
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Basal ganglia and thalamus (BGT) hypoxic-ischaemic brain injury is currently the most contentious issue in cerebral palsy (CP) litigation in South Africa (SA), and merits a consensus response based on the current available international literature. BGT pattern injury is strongly associated with a preceding perinatal sentinel event (PSE), which has a ...
I Bhorat+6 more
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Background In terms of the Nelson Mandela Fidel Castro Medical Collaboration programme, an agreement between the governments of South Africa and Cuba, cohorts of South African students receive their initial five years medical training at a Cuban ...
B. M. Donda, R. J. Hift, V. S. Singaram
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Objective Linked electronic healthcare databases are increasingly being used in observational research. The objective of this study was to investigate the impact of the choice of data source in estimating mortality following VTE, with a secondary aim to ...
Arlene Gallagher+2 more
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Background The use of simulated patients (SPs) is considered a significant resource for teaching and assessing clinical and communication skills in health professional education.
Hager ElGeed+3 more
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Background This descriptive study assessed the completeness, agreement, and representativeness of ethnicity recording in the United Kingdom (UK) Clinical Practice Research Datalink (CPRD) primary care databases alone and, for those patients registered ...
Suhail I. Shiekh+6 more
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Hypothyroidism in clinical practice
Hypothyroidism is the most common endocrine disease that was seen in the clinical practice especially for family physicians.This review article covered the important practical clinical issues for managing overt hypothyroidism, subclinical hypothyroidism and hypothyroidism during pregnancy.The clinical issues were addressed by clinical scenario followed
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