Results 131 to 140 of about 3,299,699 (357)

SYHA1813, A VEGFR and CSF1R Inhibitor, in Patients With Recurrent High‐Grade Gliomas: A Multicenter, Open‐Label Phase I Study

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Recurrent high‐grade gliomas have a poor prognosis and limited therapeutic options. This study aimed to evaluate the safety and efficacy of SYHA1813, a dual inhibitor of VEGFR and CSF1R, in patients with recurrent high‐grade gliomas.
Zhuang Kang, Shenglan Li, Liang Wang, Qianxue Chen, Weiguo Hu, Ting Lei, Ying Mao, Jing Zhang, Xiaojun Xiang, Qiming Wang, Zhengwen He, Tao Sun, Yulei Wang, Mengqian Huang, Rong Zhang, Feng Chen, Wenbin Li   +16 more
wiley   +1 more source

The Value of Clinical Practice Guidelines as Malpractice "Safe Harbors" [PDF]

, 2012
Examines the extent to which evidence-based recommendations for optimizing patient care could help reduce provider defensiveness and overutilization.
Randall R. Bovbjerg, Robert A. Berenson
core  

Nutrition and physical activity: French intergroup clinical practice guidelines for diagnosis, treatment and follow-up (SNFGE, FFCD, GERCOR, UNICANCER, SFCD, SFED, SFRO, ACHBT, AFC, SFP-APA, SFNCM, AFSOS)

, 2020
Cindy Neuzillet, Amélie Anota, Aude-Marie Foucaut, Anne‐Laure Védié, S. Antoun, D. Barn�oud, Carole Bouleuc, Frédéric Chorin, Vanessa Cottet, Éric Fontaine, Valérie Garabige, Xavier Hébuterne, F. Huguet, Astrid Lièvre, Timothée Marchal, Thomas Mouillot, Frédérique Peschaud, Didier Quilliot, Bruno Raynard, S. Schneider, Florian Scotté, Damien Vansteene, Pascale Mariani, Olivier Bouché, Francisca Joly   +24 more
openalex   +2 more sources

The Japanese Breast Cancer Society Clinical Practice Guidelines for systemic treatment of breast cancer, 2022 edition [PDF]

, 2023
Mitsuo Terada, Aki Ito, Yuichiro Kikawa, Kei Koizumi, Yoichi Naito, Tatsunori Shimoi, Mikiya Ishihara, Takashi Yamanaka, Yukinori Ozaki, Fumikata Hara, Rikiya Nakamura, Masaya Hattori, Minoru Miyashita, Naoto Kondo, Tetsuhiro Yoshinami, Masahiro Takada, Koji Matsumoto, Kazukata Narui, Shinsuke Sasada, Takayuki Iwamoto, Mitsuchika Hosoda, Yuko Takano, Takaaki Oba, Hitomi Sakai, Akari Murakami, Toru Higuchi, Junko Tsuchida, Yuko Tanabe, Tomoko Shigechi, Emi Tokuda, Michiko Harao, Shinichiro Kashiwagi, Junichi Mase, Junichiro Watanabe, Shigenori E. Nagai, Chikako Yamauchi, Yutaka Yamamoto, Hiroji Iwata, Shigehira Saji, Tatsuya Toyama   +39 more
openalex   +1 more source

Durability of Response to B‐Cell Maturation Antigen‐Directed mRNA Cell Therapy in Myasthenia Gravis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective We report the 12‐month follow‐up outcomes from a Phase 2 clinical trial (NCT04146051) evaluating Descartes‐08, a BCMA‐directed RNA chimeric antigen receptor T‐cell (rCAR‐T) therapy for refractory generalized myasthenia gravis (MG).
Nizar Chahin, Gregory Sahagian, Marc H. Feinberg, C. Andrew Stewart, Christopher M. Jewell, Metin Kurtoglu, Miloš D. Miljković, Tuan Vu, Tahseen Mozaffar, James F. Howard Jr, the MG‐001 Study Group   +10 more
wiley   +1 more source

Practice Recommendations for Genetic Testing of Ataxias

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Over the past decade, significant advances in genetic testing for ataxia have improved diagnostic accuracy, informed clinical trial eligibility, guided treatment decisions, and enabled cascade testing of at‐risk relatives. While guidance exists for other neurogenetic conditions, there are no standardized guidelines on genetic ...
Sharan R. Srinivasan, Amy D. Mook, Michelle Rochman, Jin Yun Helen Chen, Weiyi Mu, George R. Wilmot, Liana S. Rosenthal, Wendy R. Uhlmann   +7 more
wiley   +1 more source

Diagnosis and Treatment of Neurocysticercosis: 2017 Clinical Practice Guidelines by the Infectious Diseases Society of America (IDSA) and the American Society of Tropical Medicine and Hygiene (ASTMH) [PDF]

, 2017
A. Clinton White, Christina Coyle, Vedantam Rajshekhar, Gagandeep Singh, W. Allen Hauser, Aaron Mohanty, Héctor H. Garcı́a, Theodore E. Nash   +7 more
openalex   +1 more source

Cognitive Impairment in Multiple Sclerosis: The Role of Clinical and Sociodemographic Factors ‐ A Systematic Review and Meta‐Analysis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Cognitive impairment (CI) affects the quality of life in multiple sclerosis (MS). Identifying influencing factors is key to improving CI monitoring. This systematic review and meta‐analysis examines clinical and sociodemographic variables impacting the cognitive screening Symbol Digit Modalities Test (SDMT) performance across MS ...
Katalin Lugosi, Marie A. Engh, Tamás Kói, Zsolt Molnár, Gábor Csukly, Klaudia Horváth, Emma Hargitai, Péter Hegyi, Zsolt Mezei   +8 more
wiley   +1 more source

European Society of Endocrinology clinical practice guidelines on the management of adrenal incidentalomas, in collaboration with the European Network for the Study of Adrenal Tumors [PDF]

, 2023
Martin Faßnacht, Stylianos Tsagarakis, Massimo Terzolo, Antoine Tabarin, Anju Sahdev, John Newell‐Price, Iris C. M. Pelsma, Ljiljana Marina, Kerstin Lorenz, Irina Bancos, Wiebke Arlt, Olaf M. Dekkers   +11 more
openalex   +1 more source

Chronic Pain in Parkinson’s Disease: Prevalence, Sex Differences, Regional Anatomy and Comorbidities

Annals of Clinical and Translational Neurology, EarlyView.
Chronic pain affected 66.2% of 10,631 individuals with Parkinson's disease, with higher prevalence and severity in females. Pain most often involved the buttocks, lower back, neck, and knees, and was linked to depression, sleep disorders, and osteoarthritis.
Natalia S. Ogonowski, Freddy Chafota, Fangyuan Cao, Amanda Wei Yin Lim, Victor Flores‐Ocampo, Santiago Díaz‐Torres, Zuriel Ceja, Luis M. García‐Marín, Scott F. Farrell, Kishore R. Kumar, Jane Alty, George D. Mellick, Trung Thành Ngô, Miguel E. Rentería   +13 more
wiley   +1 more source