Results 51 to 60 of about 975,847 (271)

GGPONC: A Corpus of German Medical Text with Rich Metadata Based on Clinical Practice Guidelines [PDF]

arXiv, 2020
The lack of publicly accessible text corpora is a major obstacle for progress in natural language processing. For medical applications, unfortunately, all language communities other than English are low-resourced. In this work, we present GGPONC (German Guideline Program in Oncology NLP Corpus), a freely distributable German language corpus based on ...
arxiv  

Crosstalk between gut microbiota and tumor: tumors could cause gut dysbiosis and metabolic imbalance

Molecular Oncology, EarlyView.
In this research, we analyzed the relationship between gut microbiota and tumor. We discovered that both subcutaneous and metastatic tumors would alter the composition and metabolic function of gut microbiota. Meanwhile, fecal microbiota transplantation also indicated the anti‐tumor role of the gut microbiota, revealing the crosstalk between tumor and ...
Siyuan Zhang, Haimei Wen, Ying Chen, Jingya Ning, Di Hu, Yujiao Dong, Chenyu Yao, Bo Yuan, Shuanying Yang   +8 more
wiley   +1 more source

Considerations and Methodological Suggestions on Health Equity in Clinical Practice Guideline Development

Xiehe Yixue Zazhi, 2023
Health equity can narrow the health gap between different groups and enable citizens to enjoy fair health services. Clinical practice guideline makers have been paying more and more attention to health equity, and exploring and applying the consideration
GAO Yicheng, LIU Zhihan, TAO Liyuan, CAO Rui, XIA Ruyu, FENG Yuting, FANG Rui, DENG Yingjie, XIANG Wenyuan, FEI Yutong   +9 more
doaj   +1 more source

Integrative analysis of circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients: a comprehensive approach

Molecular Oncology, EarlyView.
This study simultaneously investigated circulating tumor cells (CTCs) and exosomes from small‐cell lung cancer (SCLC) patients. The elevated expression of JUNB and CXCR4 in CTCs was a poor prognostic factor for SCLC patients, whereas exosomal overexpression of these biomarkers revealed a high discrimination ability of patients from healthy individuals,
Dimitrios Papakonstantinou, Argyro Roumeliotou, Evangelia Pantazaka, Athanasios‐Nasir Shaukat, Athina Christopoulou, Angelos Koutras, Foteinos‐Ioannis Dimitrakopoulos, Vassilis Georgoulias, Anastasia Xagara, Evangelia Chantzara, Fillipos Koinis, Athanasios Kotsakis, Constantinos Stathopoulos, Galatea Kallergi   +13 more
wiley   +1 more source

Extent and feasibility of the application of the clinical pathway, clinical guideline, and practice protocol in eastern province Saudi Arabian Hospitals: A cross-sectional survey study

Journal of Nature and Science of Medicine, 2022
Background: Diversity in clinical practice may become a problem and increase the risk of errors. Several tools have been suggested to reduce this diversity and improve unification in clinical practice.
Zahra AL Qamariat, Khawlah Alkhalifah, Safia Alqarni   +2 more
doaj   +1 more source

Impact of molecular diagnostics and targeted cancer therapy on patient outcomes (MODIFY): a retrospective study of the implementation of precision oncology

Molecular Oncology, EarlyView.
The authors conducted a retrospective study of 94 patients with advanced cancer who underwent next‐generation sequencing (NGS) gene panel analysis and received targeted treatments when applicable. Results further support evidence indicating that molecular profiling provides clinical benefit.
Michaël Dang, Anna Schritz, Nikolai Goncharenko, Guy Berchem   +3 more
wiley   +1 more source

Methods for Developing Rapid and Living Evidence-based Guidelines

Xiehe Yixue Zazhi
The aims of developing rapid and living guidelines is to keep the recommendations in the guideline up-to-date. Compared with the conventional guideline, the rapid and living guideline can make better use of the existing evidence and apply and transform ...
TIAN Chen, YANG Qiuyu, SUN Mingyao, LIU Jie, TIAN Jinhui, CHEN Yaolong, YANG Kehu, GE Long   +7 more
doaj   +1 more source

Barriers to Clinical Practice Guideline Implementation Among Physicians: A Physician Survey

International Journal of General Medicine, 2021
Bashar Qumseya,1 April Goddard,1 Amira Qumseya,2 David Estores,1 Peter V Draganov,1 Christopher Forsmark1 1Division of Gastroenterology, Hepatology and Nutrition, University of Florida, Gainesville, FL, USA; 2College of Public Health & Health Professions,
Qumseya B, Goddard A, Qumseya A, Estores D, Draganov PV, Forsmark C   +5 more
doaj  

Targeted metabolomics reveals novel diagnostic biomarkers for colorectal cancer

Molecular Oncology, EarlyView.
This study employed targeted metabolomic profiling to identify 302 distinct metabolites present in platelet‐rich plasma (PRP), revealing aberrant metabolic profiles amongst individuals diagnosed with colorectal cancer (CRC). Compared to carcinoembryonic antigen (CEA) and cancer antigen 19‐9 (CA199), our metabolite panel showed improved sensitivity ...
Zuojian Hu, Fenglin Shen, Yang Liu, Ziqing Zhong, Yongling Chen, Zhiyuan Xia, Cuiju Mo, Hongxiu Yu   +7 more
wiley   +1 more source

Determinants of clinical practice guidelines’ utilization for the management of musculoskeletal disorders: a scoping review

BMC Musculoskeletal Disorders, 2021
Context Many clinical practice guidelines have been developed for the management of musculoskeletal disorders (MSDs). However, there is a gap between evidence-based knowledge and clinical practice, and reasons are poorly understood.
Delphine Sorondo, Cyrille Delpierre, Pierre Côté, Louis-Rachid Salmi, Christine Cedraschi, Anne Taylor-Vaisey, Nadège Lemeunier   +6 more
doaj   +1 more source