Results 51 to 60 of about 24,838 (241)

National Asthma Education and Prevention Program: Expert Panel Report 2. Guidelines for the diagnosis and management of asthma: Translating research for clinicians and patients

Allergology International, 1999
Asthma is a chronic, inflammatory disease of the airways that exacts a large burden of illness among patients, their families, and the health-care system. Yet advances in research have generated the means for addressing this public health problem.
Claude Lenfant, Virginia S. Taggart
doaj   +1 more source

Machine learning for identifying liver and pancreas cancers through comprehensive serum glycopeptide spectra analysis: a case‐control study

Molecular Oncology, EarlyView.
This study presents a novel AI‐based diagnostic approach—comprehensive serum glycopeptide spectra analysis (CSGSA)—that integrates tumor markers and enriched glycopeptides from serum. Using a neural network model, this method accurately distinguishes liver and pancreatic cancers from healthy individuals.
Motoyuki Kohjima, Yuko Takami, Ken Kawabe, Kazuhiro Tanabe, Chihiro Hayashi, Mikio Mikami, Tetsuya Kusumoto   +6 more
wiley   +1 more source

Oncology medications prescription in a cancer service: appropriateness to clinical practice guidelines [PDF]

Farmacia Hospitalaria, 2016
Objective: To assess prescription of oncology medications in municipal public health network of Rosario for its appropriateness to clinical practice guidelines. Methods: Descriptive pharmacoepidemiological study in adult patients in an Oncology Service
Valeria Palchik, María Luz Traverso, Marisel Colautti, Mariela Bianchi, Lucía Dolza, José María Catena, Mercedes Salamano   +6 more
doaj   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

The Shortcomings of Clinical Practice Guidelines [PDF]

Cardiology, 2015
Accumulation of medical knowledge related to diagnosis and management over the last 5-6 decades has altered the course of diseases, improved clinical outcomes and increased survival. Thus, it has become difficult for the practicing physician to evaluate the long-term effects of a particular therapy on survival of an individual patient.
Konstantinos Dean Boudoulas, Paraschos Geleris, Carl V. Leier, Harisios Boudoulas   +3 more
openaire   +3 more sources

COMORBIDITIES IN PRACTICE. CLINICAL GUIDELINES

Кардиоваскулярная терапия и профилактика, 2017
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R. G. Oganov, I. N. Denisov, V. I. Simanenkov, I. G. Bakulin, N. V. Bakulina, S. A. Boldueva, O. N Barbarash, N. P Garganeeva, V. L Doshchitsin, O. M. Drapkina, E. N. Dudinskaya, Yu. V. Kotovskaya, A. M. Lila, M. N. Mamedov, B. U. Mardanov, O. N. Miller, M. M. Petrova, Yu. M. Pozdnyakov, N. K. Runikhina, S. A. Sayganov, A. V. Tarasov, O. N. Tkacheva, A. M. Urinsky, S. A. Shalnova   +23 more
doaj   +1 more source

The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise

FEBS Open Bio, EarlyView.
Frailty syndrome exacerbates skeletal muscle degeneration via increased ECM deposition and myofiber loss. This study, using a murine model, demonstrates that endurance exercise attenuates these histopathological alterations, preserving muscle integrity. Findings support exercise as a viable strategy to counteract frailty‐induced musculoskeletal decline
Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim   +3 more
wiley   +1 more source

Development of 4T1 breast cancer mouse model system for preclinical carbonic anhydrase IX studies

FEBS Open Bio, EarlyView.
Carbonic anhydrase IX (CAIX) is a well‐recognised therapeutic target and prognostic biomarker in cancer. We developed and characterised a robust murine breast cancer model system that is suitable for CAIX studies in vitro and in vivo—it comprises both CAIX‐positive and CAIX‐negative controls and provides a solid platform for the comprehensive ...
Zane Kalniņa, Ilva Liekniņa, Svetlana Koteloviča, Ramona Petrovska, Gediminas Žvinys, Agne Petrosiute, Asta Zubrienė, Matīss Toms Laugalis, Vendija Skeltona, Juris Jansons, Madara Kreishmane, Edita Čapkauskaitė, Daumantas Matulis, Kaspars Tārs   +13 more
wiley   +1 more source

The relationship between nurses’ knowledge and perceived practice based on clinical practice guidelines of pediatrics’ pain in Guilan University of Medical Sciences

International Journal of Africa Nursing Sciences, 2021
Background: Pain is one of the most common challenging complaints of patients and can lead to significant complications. It is important to identify pediatric nurses’ knowledge about pain control methods and the management in children using clinical ...
Moluk Pouralizadeh, Masoomeh Ghasemi Ghoreishi, Maryam Niknami, Ehsan Kazemnejad-Leili   +3 more
doaj  

Knockout of the mitoribosome rescue factors Ict1 or Mtrfr is viable in zebrafish but not mice: compensatory mechanisms underlying each factor's loss

FEBS Open Bio, EarlyView.
Mitochondria contain two mitoribosome rescue factors, ICT1 and MTRFR (C12orf65). ICT1 also functions as a mitoribosomal protein in mice and humans, and its loss is lethal. Although Mtrfr knockout mice could not be generated, knockout zebrafish lines for ict1 and mtrfr were established.
Nobukazu Nameki, Chika Tomisawa, Soichiro Hoshino, Hidehiko Shimizu, Masashi Abe, Sho Arai, Kanako Kuwasako, Naoki Asakawa, Yusuke Inoue, Takuro Horii, Izuho Hatada, Masakatsu Watanabe   +11 more
wiley   +1 more source