Results 31 to 40 of about 6,182 (178)

Treatment Patterns of New Users of Fluticasone Furoate/Vilanterol in Asthma and COPD in UK Primary Care: Retrospective Cohort Study

Pulmonary Therapy, 2019
Introduction This retrospective database study explored treatment patterns and potential off-label prescribing among patients newly prescribed fluticasone furoate/vilanterol (FF/VI) in a UK primary care setting.
Daniel Dedman, Sonia J. Coton, Rebecca E. Ghosh, Wilhelmine Meeraus, Courtney Crim, Catherine Harvey, Justyna Amelio, Sarah H. Landis   +7 more
doaj   +1 more source

Cancer recording in patients with type 2 diabetes in primary care and hospital admission data

International Journal of Population Data Science, 2017
Objective Electronic health records are increasingly used to investigate associations between antidiabetic therapy and cancer. Misclassification can impact results, especially if differential between comparators.
Rachael Williams, Arlene Gallagher, Tjeerd van Staa, Tarek Hammad, Bert Leufkens, Frank de Vries   +5 more
doaj   +1 more source

Development of processes allowing near real-time refinement and validation of triage tools during the early stage of an outbreak in readiness for surge: the FLU-CATs Study

Health Technology Assessment, 2015
Background: During pandemics of novel influenza and outbreaks of emerging infections, surge in health-care demand can exceed capacity to provide normal standards of care.
Sudhir Venkatesan, Puja R Myles, Gerard McCann, Antonis A Kousoulis, Maimoona Hashmi, Rabah Belatri, Emma Boyle, Alan Barcroft, Tjeerd Pieter van Staa, Jamie J Kirkham, Jonathan S Nguyen Van Tam, Timothy J Williams, Malcolm G Semple   +12 more
doaj   +1 more source

Burden of allergic rhinitis in the United Kingdom

Frontiers in Allergy
IntroductionAllergic rhinitis (AR) is a systemic respiratory condition that is associated with a considerable humanistic burden and is frequently underdiagnosed.
Michael Jones, Hilary Shepherd, Diane Hatziioanou, Daphne Martin, Chisomo Mutafya, Ulf Bohman, Susan Hodgson, Rachael Williams   +7 more
doaj   +1 more source

The cost of primary care consultations associated with long COVID in non-hospitalised adults: a retrospective cohort study using UK primary care data

BMC Primary Care, 2023
Background The economic impact of managing long COVID in primary care is unknown. We estimated the costs of primary care consultations associated with long COVID and explored the relationship between risk factors and costs.
Jake Tufts, Naijie Guan, Dawit T Zemedikun, Anuradhaa Subramanian, Krishna Gokhale, Puja Myles, Tim Williams, Tom Marshall, Melanie Calvert, Karen Matthews, Krishnarajah Nirantharakumar, Louise J Jackson, Shamil Haroon   +12 more
doaj   +1 more source

Are we missing lifetime COPD diagnosis among people with COPD recorded death? A population-based retrospective cohort study

BJGP Open, 2022
Background: The British Lung Foundation (BLF) has previously estimated that there are 2.2 million people in the UK who have symptoms, but no diagnosis, of chronic obstructive pulmonary disease (COPD). Aim: To investigate the proportion of patients with a
Alicia Gayle, Alexandra Lenoir, Cosetta Minelli, Jennifer Quint   +3 more
doaj   +1 more source

Risk of fracture with thiazolidinediones: an individual patient data meta-analysis

Frontiers in Endocrinology, 2013
Background: The use of thiazolidinediones (TZDs) has been associated with increased fracture risks. Our aim was to estimate the risk of fracture with TZDs in three different healthcare registries, using exactly the same study design, and to perform an ...
Marloes T Bazelier, Frank ede Vries, Frank ede Vries, Frank ede Vries, Peter eVestergaard, Ron M.C. Herings, Arlene M. Gallagher, Hubert G.M. Leufkens, Tjeerd-Pieter evan Staa, Tjeerd-Pieter evan Staa, Tjeerd-Pieter evan Staa   +10 more
doaj   +1 more source

Fidelity Assessment of a Clinical Practice Research Datalink Conversion to the OMOP Common Data Model [PDF]

Drug Safety, 2014
The unique structure and coding of the Clinical Practice Research Datalink (CPRD) presents challenges for epidemiologic analysis and for comparisons with other databases. To address this limitation we sought to transform CPRD into the Observational Medical Outcomes Partnership (OMOP) Common Data Model (CDM).An extraction, transformation and loading ...
Matcho, Amy, Ryan, Patrick, Fife, Daniel, Reich, Christian   +3 more
openaire   +2 more sources

What are the implications of using individual and combined sources of routinely collected data to identify and characterise incident site-specific cancers? a concordance and validation study using linked English electronic health records data

BMJ Open, 2020
Objectives To describe the benefits and limitations of using individual and combinations of linked English electronic health data to identify incident cancers.Design and setting Our descriptive study uses linked English Clinical Practice Research ...
Rachael Williams, Helen Strongman, Krishnan Bhaskaran   +2 more
doaj   +1 more source

Impact of Atrial Fibrillation Awareness Campaigns: Interrupted Time Series Using the Clinical Practice Research Datalink [PDF]

Future Cardiology, 2019
Aim: This study investigated whether the rates of atrial fibrillation (AF) consultations changed following AF awareness campaigns in England. Materials & methods: Among adults in the Clinical Practice Research Datalink, Poisson regression was used to model weekly rates of AF-related consultations over time.
Victoria, Allan, Cormac J, Sammon, Laura, McDonald, Faisal, Mehmud, Raza, Alikhan, Sreeram V, Ramagopalan   +5 more
openaire   +2 more sources