Results 191 to 200 of about 15,228,231 (351)

Transcatheter targeted myocardial restoration using hydrogel-based cell-free compound: Toward an adoptable clinical protocol. [PDF]

JTCVS Open, 2023
Sazzad F, Kuzemczak M, Chen ZJ, Tan JF, Ong ZX, Richards AM, Kofidis T.   +6 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

A Generative AI Framework for Cognitive Intervention in Older Adults: An Integrated Engineering Design and Clinical Protocol. [PDF]

Healthcare (Basel)
Jeong T, Hwang G, Kim DY.
europepmc   +1 more source

American Association for the Surgery of Trauma/American College of Surgeons Committee on Trauma clinical protocol for management of acute respiratory distress syndrome and severe hypoxemia. [PDF]

J Trauma Acute Care Surg, 2023
Fawley JA, Tignanelli CJ, Werner NL, Kasotakis G, Mandell SP, Glass NE, Dries DJ, Costantini TW, Napolitano LM.   +8 more
europepmc   +1 more source

SPIRIT 2013 statement: defining standard protocol items for clinical trials.

Annals of Internal Medicine, 2013
A. Chan, J. Tetzlaff, D. Altman, A. Laupacis, P. Gøtzsche, K. Krleza-Jeric, A. Hrõbjartsson, H. Mann, K. Dickersin, J. Berlin, C. Doré, W. Parulekar, W. Summerskill, T. Groves, K. Schulz, H. Sox, F. Rockhold, D. Rennie, D. Moher   +18 more
semanticscholar   +1 more source

Metastasis on pause: How dormant tumor cells stay hidden within the tumor microenvironment and evade immune surveillance

Molecular Oncology, EarlyView.
Dormant cancer cells can hide in distant organs for years, evading treatment and the immune system. This review highlights how signals from the surrounding tissue and immune environment keep these cells inactive or trigger their reawakening. Understanding these mechanisms may help develop therapies to eliminate or control dormant cells and prevent ...
Kanishka Tiwary, Jose Javier Bravo‐Cordero   +1 more
wiley   +1 more source

The establishment of a clinical protocol for hostages returning from captivity. [PDF]

BMC Emerg Med
Trotzky D, Segal I, Koren R, Tal O, Pachys G, Goltzman G, Or K, Alpro M, Zaidenstein R, Bachar M, Berzon B, Vissoker RE, Hartmann I, Avraham M, Shinar V, Azar A, Korach OL.   +16 more
europepmc   +1 more source

Spontaneous Renal Hemorrhage: A Case Report and Clinical Protocol. [PDF]

Cureus, 2021
Antonescu O, Duhamel M, Di Giacinto B, Spain J.   +3 more
europepmc   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

A clinical protocol for group-based ketamine-assisted therapy in a community of practice: the Roots To Thrive model. [PDF]

Front Psychiatry
Dames S, Kryskow P, Tsang VWL, Argento E.   +3 more
europepmc   +1 more source