Results 121 to 130 of about 393,743 (306)

NNMT Orchestrates Metabolic‐Epigenetic Reprogramming to Drive Macrophage‐Myofibroblast Transition in Hypertrophic Scarring

open access: yesAdvanced Science, EarlyView.
In macrophage‐myofibroblast transition, upregulated NNMT depletes S‐Adenosylmethionine‌ (SAM) and nicotinamide adenine dinucleotide(NAD+), thereby triggering epigenetic reprogramming via Histone H3 Lysine 27 acetylation (H3K27ac) accumulation at the promoter region of master transcription factor Prrx1.
Xiwen Dong   +11 more
wiley   +1 more source

Love Addiction - Current Diagnostic and Therapeutic Paradigms in Clinical Psychology. (v2). [PDF]

open access: yesHealth Psychol Res, 2023
Maglia MG   +3 more
europepmc   +1 more source

Ecologically‐Valid Emotion Signatures Enhance Mood Disorder Diagnostics

open access: yesAdvanced Science, EarlyView.
This study identifies ecologically‐valid Divergent Emotional Functional Networks (DEFN), derived from dynamic functional connectivity during naturalistic movie watching. The DEFN reliably enhances diagnostic accuracy for mood disorders, including major depressive and bipolar disorders, demonstrating strong reproducibility across demographic factors and
Shuyue Xu   +6 more
wiley   +1 more source

Actual problems of medical psychology. Conference to the 85th anniversary of Yury Fedorovich Polyakov

open access: yesКлиническая и специальная психология, 2013
The article gives materials and information about the Russian scientific and practical conference in memory of Y.Polyakov (1927-2002) “Theoretical and practical problems of medical (clinical) psychology”, which was held on February 14-15.
M.Veshchikova, M.Zvereva
doaj  

Clinical Psychology and the COVID-19 Pandemic: A Mixed Methods Survey Among Members of the European Association of Clinical Psychology and Psychological Treatment (EACLIPT). [PDF]

open access: yesClin Psychol Eur, 2023
Asbrand J   +11 more
europepmc   +1 more source

A Symposium to connect Psychological Support with Psychology : For The Clinical Psychology based on Essential Psychology

open access: diamond, 2019
Takashi Sugiyama   +4 more
openalex   +2 more sources

Neddylation Targets and Stabilizes NLRP3 to Augment Inflammasome‐Mediated Colitis and Mood Disorder

open access: yesAdvanced Science, EarlyView.
NLRP3 inflammasome contributes to colitis and mood disorder. This study demonstrates that neddylation targets NLRP3 at K287, which hinders its interaction with K48‐linked ubiquitination E3 Trim31 and thereby stabilizes it. Neddylation blockade in myeloid cells and microglia mitigates DSS‐induced colitis and psychological stress‐induced anxiety‐like ...
Wenbin Gai   +13 more
wiley   +1 more source

Perfluorooctanoic Acid Exposure Causes Macrophage Ammonia Retention and Induces Spontaneous Miscarriages

open access: yesAdvanced Science, EarlyView.
PFOA exposure induces pregnancy loss by promoting glutaminolysis, which further causes ammonia accumulation in macrophages. Cellular ammonia retention results in damage to mitochondria and lysosomes, which leads to cell death eventually. Impaired lysosomes also decrease the secretion of the Cathepsin B (CTSB), and attenuate macrophage infiltration and ...
Yongbo Zhao   +6 more
wiley   +1 more source

Home - About - Disclaimer - Privacy