Results 151 to 160 of about 478,037 (310)

IL‐7R‐Enriched Extracellular Vesicles From the Thymus Drive Colitis via Promoting Neutrophil Extracellular Trap Formation

open access: yesAdvanced Science, EarlyView.
Inflammatory bowel disease (IBD) pathogenesis remains unclear. This study reveals that thymus‐originated IL‐7R‐enriched extracellular vesicles exacerbate colitis by promoting neutrophil extracellular traps via a thymus‐gut axis, uncovering an inter‐organ communication mechanism in inflammatory bowel disease pathogenesis.
Yao Liao   +21 more
wiley   +1 more source

Amuc_1473 Links Gut Microbes to Skeletal Homeostasis and Counteracts Multifactorial Osteoporosis

open access: yesAdvanced Science, EarlyView.
Amuc_1473, a previously uncharacterized protein enriched in Akkermansia muciniphila‐derived extracellular vesicles, is identified as a gut–bone messenger that promotes osteogenesis and inhibits osteoclastogenesis by engaging transcriptional and translational regulators in bone cells.
Shan‐Shan Rao   +28 more
wiley   +1 more source

Human‐Centered Innovation: Precision Nutrition and the Future of Food

open access: yesAdvanced Science, EarlyView.
ABSTRACT Nutritional science is moving beyond one‐size‐fits‐all recommendations toward more precise and personalized approaches, yet its implementation pathway remains unclear. This paper proposes a human‐centered precision nutrition framework that highlights the central roles of artificial intelligence (AI), food innovation, and human agency.
Shanshan Zhang   +3 more
wiley   +1 more source

Actual problems of medical psychology. Conference to the 85th anniversary of Yury Fedorovich Polyakov

open access: yesКлиническая и специальная психология, 2013
The article gives materials and information about the Russian scientific and practical conference in memory of Y.Polyakov (1927-2002) “Theoretical and practical problems of medical (clinical) psychology”, which was held on February 14-15.
M.Veshchikova, M.Zvereva
doaj  

Widening access to clinical psychology: regional and local initiatives [PDF]

open access: yes, 2013
The British Psychological Society (Turpin & Fensom, 2004) made recommendations for addressing the under-representation of those from minority ethnic backgrounds in professional psychology. The impact of two regional and local initiatives to widen access
Chahal, K.   +3 more
core  

Single‐Cell Transcriptomic Analysis of Tumor Heterogeneity and the Microenvironment in Pseudomyxoma Peritonei

open access: yesAdvanced Science, EarlyView.
This study presents a single‐cell atlas of pseudomyxoma peritonei spanning primary and paired metastatic lesions. Distinct epithelial substates, stromal remodeling, immune exclusion, lipid metabolic reprogramming, and a candidate angiogenic network were identified in metastatic lesions.
Xi Li   +14 more
wiley   +1 more source

Fitness to practise in clinical psychology training [PDF]

open access: yes, 2012
Assessment of Fitness to Practise (FTP) guidelines within clinical psychology training programmes requires balancing the individual student’s right to pursue their vocation of interest and the rights of others with whom that person comes in contact, most
Sofronoff, Kate, Helmes, Edward
core  

Multimodal Imaging Reveals Rapid Catecholamine Uptake and Release by Neutrophils

open access: yesAdvanced Science, EarlyView.
We show that immune cells (neutrophils) synthesize, uptake, and store catecholamine neurotransmitters such as dopamine or adrenaline. They also release them in response to specific stimuli (serotonin), which we directly visualize using fluorescent nanosensors. We further demonstrate that catecholamines affect neutrophil functions (NETosis) and platelet
Jennifer Mohr   +19 more
wiley   +1 more source

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