Results 201 to 210 of about 4,224,042 (268)

Clinical risk prediction in lung adenocarcinoma using MAL gene and tumor microenvironment features. [PDF]

Discov Oncol
Guo L, Li J.
europepmc   +1 more source

Longitudinal genome‐wide aneuploidy measurements in circulating cell‐free DNA to predict lack of benefit from pembrolizumab in patients with metastatic urothelial cancer

Molecular Oncology, EarlyView.
Many patients with urothelial cancer do not benefit from treatment with pembrolizumab, while at risk of severe side effects. Changes in the levels of circulating tumor DNA early during treatment, measured by a simple and affordable assay that can be easily implemented in the clinic, can be used as a prognostic tool to identify these patients.
Youssra Salhi, Stavros Makrodimitris, Sandra van Wilpe, Iris te Paske, Vanja de Weerd, Corine M. Beaufort, Hans M. Westgeest, Jens Voortman, Maureen J. B. Aarts, Maud Rijnders, Astrid A. M. van der Veldt, Ronald de Wit, Niven Mehra, Saskia M. Wilting, Debbie G. J. Robbrecht   +14 more
wiley   +1 more source

Clinical risk factors and predictive value of thin-section CT for bronchial mucus plugs in pediatric mycoplasma pneumoniae pneumonia. [PDF]

BMC Infect Dis
Li L, Zhang Z, Yuan F, Song C, Chen H, Wang Y, Wang Y, Wang K.   +7 more
europepmc   +1 more source

MITF maintains genome stability in nonmelanocyte lineages

Molecular Oncology, EarlyView.
MITF is essential for melanocyte survival and acts as an oncogene in 10%–20% of melanomas. We show that MITF depletion causes genome instability in nonmelanocytic cells, leading to LATS2‐mediated P53 activation, cell cycle arrest, and apoptosis. This study highlights the role of MITF as a genome maintenance factor beyond the melanocyte lineage. Created
Drifa H. Gudmundsdottir, Adrián López García de Lomana, Thejus B. Venkatesh, Kritika Kirty, Snaevar Sigurdsson, Linda Vidarsdottir, Ramile Dilshat, Erla Sveinbjornsdottir, Snaedis Ragnarsdottir, Daniel H Magnusson, Maria R. Bustos, Eirikur Steingrimsson, Thorkell Gudjonsson, Stefan Sigurdsson   +13 more
wiley   +1 more source

Intraductal Carcinoma of the Prostate: Impact of Grading Methods on Clinical Risk Stratification. [PDF]

Int J Surg Pathol
Murphy P, Ni Mhaolcatha S, Chen-Maxwell D, Prendeville S.   +3 more
europepmc   +1 more source

Functional Walking Capacity as a Screening Indicator for Peripheral Arterial Disease in Patients with Type 2 Diabetes Mellitus: Development of a Clinical Risk Equation. [PDF]

Diagnostics (Basel)
Chuatrakoon B, Nantakool S, Waisayanand N, Reanpang T, Wanichsuksombat L, Konghakote S, Phisitbuntoon K, Jaiin N, Rattanaphan S.   +8 more
europepmc   +1 more source

Development and validation of a clinical risk stratification model for lumbar vertebral compression fractures in patients with lumbar disc herniation. [PDF]

Bone Rep
Liu D, Wang S, Zhu L, Tang G, Xue S, Jiang B, Fang X, Li L, Liu T, Zhou Z, Liu Y.   +10 more
europepmc   +1 more source

Development and Validation of a Clinical Risk Score for Predicting Postpartum Hemorrhage in Women with Antepartum Hemorrhage. [PDF]

J Mother Child
Asati S, Asati P, Gupta A, Gothwal M.
europepmc   +1 more source

Beyond Thresholds: CMV Replication Kinetics as Early Predictors of Clinical Risk in Transplant Recipients. [PDF]

Infect Drug Resist
Kleiboeker HL, Descourouez JL, Saddler C, Jorgenson MR.   +3 more
europepmc   +1 more source

Omission of contralateral biopsies in unilateral MRI-suspicious prostate cancer has minimal impact on clinical risk assessment. [PDF]

BJUI Compass
van den Bosch SM, van den Kroonenberg DL, van Bruggen BW, de Bie KCC, Jager A, Postema AW, Oprea-Lager DE, Schoots IG, Oddens JR, Vis AN.   +9 more
europepmc   +1 more source