Results 21 to 30 of about 4,224,042 (268)

Inflammatory marker changes in a 24-month dietary and physical activity randomised intervention trial in postmenopausal women

Scientific Reports, 2020
Chronic low-grade inflammation plays a role in the pathogenesis of several chronic diseases including cancer. Physical activity (PA) and diet have been supposed to modulate inflammatory markers.
G. Masala, B. Bendinelli, C. Della Bella, M. Assedi, S. Tapinassi, I. Ermini, D. Occhini, M. Castaldo, C. Saieva, S. Caini, M. M. D’Elios, D. Palli   +11 more
doaj   +1 more source

Patient Safety Incidents in Inpatient Psychiatric Settings: An Expert Opinion Survey

Behavioral Sciences
Patient safety in psychiatric inpatient facilities remains under-researched despite its crucial importance. This study aims to address this gap by using expert opinion to estimate the frequency of diverse patient safety incidents (PSIs) in psychiatric ...
Sophia Russotto, Andrea Conti, Kris Vanhaecht, José Joaquín Mira, Massimiliano Panella   +4 more
doaj   +1 more source

Structured Benefit-Risk Assessment of a New Quadrivalent Meningococcal Conjugate Vaccine (MenACYW-TT) in Individuals Ages 12 Months and Older

Infectious Diseases and Therapy, 2023
Introduction A favorable benefit-risk balance is required to support licensure of biologics, in keeping with regulatory agencies’ evolving recommendations, including the United States Food and Drugs Administration.
David Neveu, Tamala Mallett Moore, Betzana Zambrano, Aiying Chen, Marie-Laure Kürzinger, Lydie Marcelon, Mandeep Singh Dhingra   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Prognostic Indicators of Severe Dengue Infection in Adult Patients in Thailand

Tropical Medicine and Infectious Disease
Background: Dengue infection is a spreading vector borne disease with most severe infection-related fatalities occurring in adults. This study was conducted to explore prognostic indicators of dengue infection severity.
Patcharin Khamnuan, Surangrat Pongpan, Pantitcha Thanatrakolsri, Supa Vittaporn, Punnaphat Daraswang, Sirawan Samsee   +5 more
doaj   +1 more source

Effect of Plant Protein on Blood Lipids: A Systematic Review and Meta‐Analysis of Randomized Controlled Trials

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2017
BackgroundThere is a heightened interest in plant‐based diets for cardiovascular disease prevention. Although plant protein is thought to mediate such prevention through modifying blood lipids, the effect of plant protein in specific substitution for ...
Siying S. Li, Sonia Blanco Mejia, Lyubov Lytvyn, Sarah E. Stewart, Effie Viguiliouk, Vanessa Ha, Russell J. de Souza, Lawrence A. Leiter, Cyril W. C. Kendall, David J. A. Jenkins, John L. Sievenpiper   +10 more
doaj   +1 more source

Important Food Sources of Fructose‐Containing Sugars and Incident Hypertension: A Systematic Review and Dose‐Response Meta‐Analysis of Prospective Cohort Studies

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease, 2019
Background Sugar‐sweetened beverages are associated with hypertension. We assessed the relation of important food sources of fructose‐containing sugars with incident hypertension using a systematic review and meta‐analysis of prospective cohort studies ...
Qi Liu, Sabrina Ayoub‐Charette, Tauseef Ahmad Khan, Fei Au‐Yeung, Sonia Blanco Mejia, Russell J. de Souza, Thomas M.S. Wolever, Lawrence A. Leiter, Cyril W.C. Kendall, John L. Sievenpiper   +9 more
doaj   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source

Out‐of‐Distribution Detection as a Risk‐Control Strategy for Medical Classification Machine Learning Models

Clinical and Translational Science
Recent advances in artificial intelligence (AI) and machine learning (ML) algorithms have significantly broadened the scope in which these algorithms are deployed.
Chu Weng, Joshua Ward, Wesley Lin, Sherry Dong, Qi Liu, Hanrui Zhang   +5 more
doaj   +1 more source