Results 21 to 30 of about 1,898,406 (260)

Population Pharmacokinetic and Pharmacodynamic Analysis of Dalbavancin for Long-Term Treatment of Subacute and/or Chronic Infectious Diseases: The Major Role of Therapeutic Drug Monitoring

Antibiotics, 2022
A population pharmacokinetic analysis of dalbavancin was conducted in patients with different infection sites. Non-linear mixed effect modeling was used for pharmacokinetic analysis and covariate evaluation.
Pier Giorgio Cojutti, Sara Tedeschi, Milo Gatti, Eleonora Zamparini, Marianna Meschiari, Paola Della Siega, Maria Mazzitelli, Laura Soavi, Raffaella Binazzi, Elke Maria Erne, Marco Rizzi, Anna Maria Cattelan, Carlo Tascini, Cristina Mussini, Pierluigi Viale, Federico Pea   +15 more
doaj   +1 more source

Summary of final data from the 9-valent human papillomavirus vaccine pregnancy registry (2014–2021)

Human Vaccines & Immunotherapeutics
The 9-valent human papillomavirus (9vHPV) vaccine targets human papillomavirus (HPV) types 6/11/16/18/31/33/45/52/58. Although its use in pregnant women is not recommended, inadvertent exposures during early pregnancy could occur as the indicated age ...
Cathy Hardalo, Ann Marko, Brittany Sciba, Debora Rausch, Bridget Sieger, Ronald Leong, Joseph E. Tota, Alain Luxembourg, Susan S. Kaplan   +8 more
doaj   +1 more source

Accurate and Sensitive UHPLC–Tandem Mass Spectrometry Sequential Methods for Therapeutic Drug Monitoring of Aztreonam/Avibactam in Human Plasma

Pharmaceutics
Background/Objectives: The aztreonam/avibactam combination represents a promising therapeutic option for severe infections caused by multidrug-resistant Gram-negative pathogens, particularly in critically ill patients.
Ilaria Trozzi, Beatrice Giorgi, Riccardo De Paola, Milo Gatti, Federico Pea   +4 more
doaj   +1 more source

A 12-year epidemiological study of Acinetobacter baumannii from blood culture isolates in a single tertiary-care hospital using polymerase chain reaction (PCR)–based open reading frame typing

Antimicrobial Stewardship & Healthcare Epidemiology, 2022
Objective: Acinetobacter baumannii is a causative agent of healthcare-associated infections, and the introduction and spread of A. baumannii that has acquired drug resistance within a hospital are serious healthcare problems.
Yuji Fujikura, Takaaki Hamamoto, Atsushi Yuki, Ayumi Sampei, Nozomi Ichie, Kazuho Takamizawa, Sakika Nomura, Yusuke Serizawa, Tomohiro Ohno, Hironori Tsujimoto   +9 more
doaj   +1 more source

Two Comprehensive Liquid Chromatography High-Resolution Mass Spectrometry (UPLC-MS/MS) Multi-Methods for Real-Time Therapeutic Drug Monitoring (TDM) of Five Novel Beta-Lactams and of Fosfomycin Administered by Continuous Infusion

Pharmaceutics
Background/Objectives: Therapeutic drug monitoring (TDM) of β-lactams (BL), BL/β-lactamase inhibitor (BLI) combinations (BL/BLIc), and of fosfomycin may play a key role in optimizing antimicrobial therapy and in preventing resistance development ...
Ilaria Trozzi, Beatrice Giorgi, Riccardo De Paola, Milo Gatti, Federico Pea   +4 more
doaj   +1 more source

Relationship Between Patient Safety attitude and Clinical Risk Management as Perceived by Nursing personnel [PDF]

Alexandria Scientific Nursing Journal
Background: Patient safety attitude is essential for effective clinical riskmanagement, as it enables healthcare personnel to identify, report, and addresspotential risks proactively.
Noura Matrawy ELshahat Elkosbary, Hala Ahmed Abdou, Nancy Sabry Elleithy   +2 more
doaj   +1 more source

Diabetes Care in French Guiana: The Gap Between National Guidelines and Reality

Frontiers in Endocrinology, 2021
IntroductionFrench Guiana is a multicultural overseas territory in the Amazon, where precariousness and difficulties in access to care are widespread. The prevalence of diabetes is double that of other French departments, and cardiovascular morbidity and
Christine Sudre, Hélène Duplan, John Bukasakakamba, Mathieu Nacher, Pascale Peyre-Costa, Nadia Sabbah, Nadia Sabbah   +6 more
doaj   +1 more source

European Standard Clinical Practice Guideline and EXPeRT Recommendations for the Diagnosis and Management of Gastroenteropancreatic Neuroendocrine Neoplasms in Children and Adolescents

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Pediatric gastroenteropancreatic neuroendocrine neoplasms (GEP‐NENs) are extremely rare and clinically heterogeneous. Management has largely been extrapolated from adult practice. This European Standard Clinical Practice Guideline (ESCP), developed by the EXPeRT network in collaboration with adult NEN experts, provides (adult) evidence ...
Michaela Kuhlen, Calogero Virgone, Antje Redlich, Michael Abele, Ricardo Lopez‐Almaraz, Tal Ben‐Ami, Ewa Bien, Gianni Bisogno, Maja Mazic Cesen, Andrea Ferrari, Malgorzata A. Krawczyk, Yves Reguerre, Dominik T. Schneider, Ines B. Brecht, Charlotte Rigaud, Bilgehan Yalcin, Rainer Claus, Christian Vokuhl, Constantin Lapa, Jörg Fuchs, Segolene Hescot, Thomas Walter, Julien Hadoux, Daniel Orbach   +23 more
wiley   +1 more source

Are Fertility Preservation Procedures Before Gonadotoxic Therapy and Hematopoietic Stem Cell Transplantation Feasible and Safe in Very Young Children? A Retrospective Cohort Study

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian, Yannick Braun, Till‐Martin Theilen, Anke Barnbrock, Theresa Rohm, Fabienne Hammant, Nicole Sänger, Aynura Abbasova‐Semiz, Jan‐Henning Klusmann, Thomas Klingebiel, Udo Rolle, Peter Bader, Henning C. Fiegel, Andrea Jarisch   +13 more
wiley   +1 more source

Central Nervous System Neuroblastoma, FOXR2‐Activated: A Pooled Analysis of Published Clinical Outcomes

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Central nervous system (CNS) neuroblastoma, FOXR2‐activated, is a recently recognized entity in the WHO CNS5 classification, defined by activation of the FOXR2 transcription factor and unique histopathological features. This review synthesizes available literature and pooled clinical data, providing insight into demographics ...
Sudarshawn Damodharan, Mohamed S. Abdelbaki   +1 more
wiley   +1 more source