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, 2023 This is the April 2023 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grants
UMass Center for Clinical and Translational Science
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Children with acute lymphoblastic leukemia (ALL) are at risk of severe outcomes from SARS‐CoV‐2 (SCV2). In the post‐pandemic context, where most children have been infected with SCV2, there are limited data on whether vaccination remains beneficial in children with ALL.
Janna R. Shapiro +11 more
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Medical Laboratory Sciences: Fall 2023 Clinical Rotation
, 2023 On photo: left to right - top row: Amanda Bennett, Christine Bui, Patricia ChanSecond row (left to right): Hailey Eschliman, Fatemeh Farokhi, Autumn GintherThird row (left to right): Michelle Le, Julia-Q ManouphathBottom row (left to right): Catherine ...
Medical Laboratory Sciences +1 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm +11 more
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Medical Laboratory Sciences: Spring 2021 Clinical Rotation
, 2021 On photo: left to right - top row: Jesse Anderson, Chelsea Bui, Chi HuynhSecond row (left to right): Brandon Koch, Emily Nguyen, Thomas SchumanThird row (left to right): Trey Schwarz, Bradley Toon, Cuong Chris TranBottom row (left to right): Kade Wessel,
Medical Laboratory Sciences +1 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke +4 more
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Medical Laboratory Sciences: Fall 2022 Clinical Rotation
, 2022 On photo: left to right - top row: Eileen Beckmeyer, Grayce Berntsen, Hayden Budke, Alexander CollierMiddle row (left to right): Kaitlyn Gile, Matilde Gonzalez, Karsen Klein, Hannah McintoshBottom row (left to right): Stephanie Pham, Chad Rosenberger ...
Medical Laboratory Sciences +1 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook +6 more
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Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Central nervous system (CNS) involvement in childhood acute lymphoblastic leukemia (ALL) is assessed by cell counting and cytomorphology from cerebrospinal fluid (CSF) and is used for treatment stratification worldwide. The ratio of “CNS2” patients in clinical trials ranges from 3% to 40%, with unclear prognostic significance ...
Laura Almási +14 more
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Majalah Kedokteran AndalasTujuan : Penelitian ini bertujuan untuk melihat hubungan hidronefrosis pra operasi dengan penurunan hemoglobin pasca PCNL pada penderita batu ginjal; Metode: Penelitian ini merupakan penelitian analitik dengan pendekatan prospektif.
Febby Genta Wahyuni +5 more
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