Results 81 to 90 of about 19,121,257 (190)

Significance of positive semi-quantitative PCR tests on bronchoalveolar lavage for Pneumocystis jirovecii pneumonia in HIV-negative immunocompromised ICU patients with acute respiratory failure

Annals of Intensive Care
Context: Real-time PCR (rt-PCR) using cycle threshold (Ct) is a semi-quantitative way to assess DNA amounts, which has become broadly used to diagnose Pneumocystis jirovecii pneumonia (PJP) in non-HIV immunocompromised patients.
Louis-Maxime Vaconsin, Christine Bonnal, Nicolas Argy, Julien Dessajan, Paul-Henri Wicky, Michael Thy, Etienne de Montmollin, Romain Sonneville, Lila Bouadma, Sandrine Houzé, Jean-François Timsit   +10 more
doaj   +1 more source

Incidence and outcomes of extubation failure in mechanically ventilated patients with cirrhosis: a post-hoc analysis of a prospective multicenter study

Annals of Intensive Care
Background: Patients with comorbidities who are liberated from invasive mechanical ventilation could be at risk of extubation failure in the intensive care unit (ICU). Incidence and associated outcomes of reintubation in patients with cirrhosis have been
Yassir Aarab, Joris Pensier, Fanny Garnier, Clement Monet, Ines Lakbar, Gerald Chanques, Audrey de Jong, Mathieu Capdevila, Samir Jaber   +8 more
doaj   +1 more source

UMCCTS Newsletter, December 2024 [PDF]

This is the December 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core   +1 more source

Distinct diurnal temperature rhythm patterns in critical illness myopathy: secondary analysis of two prospective trials

Annals of Intensive Care
Background: Critical illness myopathy (CIM) increases mortality and causes long-term disabilities. CIM is characterized by reduced muscle excitability, muscle atrophy, weakness, and impaired glucose metabolism.
D. Mewes, S. Weber-Carstens, K. Rubarth, S.D. Boie, C. Spies, A. Kramer, J. Fielitz, T. Wollersheim, B. Ananthasubramaniam, F. Braune, L. Hancke, L. Spies, F. Balzer, L.J. Engelhardt   +13 more
doaj   +1 more source

UMCCTS Newsletter, October 2024 [PDF]

This is the October 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through ...
UMass Center for Clinical and Translational Science
core   +1 more source

Multimodal assessment of peripheral perfusion in critically ill patients: a pilot study

Annals of Intensive Care
Background: Impaired peripheral perfusion is linked to poor outcomes in critically ill patients, but the relationships among common bedside assessment tools remain unclear.
Zoé Demailly, Elena Modica, Eva Vitali, Francisco Sousa, Carlotta Dragoni, Irene Sbaraini Zernini, Claudio Annicchiarico, Charles Dehout, Fabienne Tamion, Emmanuel Besnier, Hassane Njimi, Elaine Cavalcante dos Santos, Fabio Silvio Taccone   +12 more
doaj   +1 more source

Clinical medication review: one step beyond: Computer rules of personal goals? [PDF]

, 2019
In this ageing society, older persons are using more and more medications for chronic diseases. During a clinical medication review, the community pharmacist evaluate all the medication use together with the patient in a personal conversation.
Verdoorn, Marguerita Alexandra, Afd Pharmacoepi & Clinical Pharmacology, Pharmacoepidemiology and Clinical Pharmacology   +2 more
core  

UMCCTS Newsletter, April 2024 [PDF]

This is the April 2024 issue of the UMass Center for Clinical and Translational Science Newsletter containing news and events of interest.Supported by the National Center for Advancing Translational Sciences, National Institutes of Health, through Grants
UMass Center for Clinical and Translational Science
core   +1 more source

Do diabetes and poor control of acute stress-related hyperglycemia increase the risk of ICU-acquired infections? A retrospective assessment in patients with septic shock

Annals of Intensive Care
Background: Patients with septic shock who survive the early resuscitation phase are prone to ICU-acquired infections. Although hyperglycemia harbors potent immunomodulatory properties, the impact of preexisting diabetes and the control of acute stress ...
Alice Friol, Clément Devautour, Anna Semenov, Juliette Pelle, Marie Renaudier, Sarah Benghanem, Alain Cariou, Jean-Paul Mira, Julien Charpentier, Frédéric Pène   +9 more
doaj   +1 more source

Pharmacokinetics of novel anticancer drugs and dynamics of circulating tumor cells in early clinical studies [PDF]

, 2011
Cancer has an enormous impact on the lives of patients and on society and there is an urgent need for improvements in therapy. In this thesis, early-clinical studies into both safety and pharmacokinetics of novel anti-cancer drugs as well as into ...
Devriese, L.A., Clinical Pharmacology, Sub Clinical Pharmacology   +2 more
core   +1 more source