Results 91 to 100 of about 9,880,911 (259)

GENE THERAPY

open access: yesZdravniški Vestnik, 2003
Background. Gene therapy is a novel approach to treat, cure, or ultimately prevent disease by changing the expression of person’s genes.Gene therapy is in its inflancy, and current gene therapy is primarily experimental, with most human clinical trials ...
Irena Milisav
doaj  

Secure, reliable and dynamic access to distributed clinical data [PDF]

open access: yes, 2006
An abundance of statistical and scientific data exists in the area of clinical and epidemiological studies. Much of this data is distributed across regional, national and international boundaries with different policies on access and usage, and a ...
Ajayi, O., Sinnott, R.O., Stell, A.J.
core   +3 more sources

Feasibility and Safety of High‐Dose Proton Re‐Irradiation in Recurrent Pediatric Central Nervous System Tumors: A Single‐Institution Retrospective Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Purpose Pediatric central nervous system (CNS) tumors often recur despite multimodality therapy. Although re‐irradiation (re‐RT) has historically been limited by concerns for severe late toxicities, modern techniques have renewed interest in this approach. Proton therapy provides dosimetric advantages that may enable curative re‐treatment with
Jin‐Ho Song   +15 more
wiley   +1 more source

Defining Roles in Pediatric Palliative Care: Perspectives From Oncology and Palliative Care Teams

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Early integration of pediatric palliative care (PPC) is associated with improved symptom management, quality of life, and healthcare utilization for children with cancer. Despite this, variation persists in how PPC is understood, operationalized, and integrated within pediatric oncology programs. In particular, ambiguity surrounding
Leeat Granek   +13 more
wiley   +1 more source

Editorial: Biomarkers and immunotherapy of hepatic-biliary-pancreatic cancers

open access: yesFrontiers in Oncology, 2023
Yawei Qian, Wenyu Jia, Hongda Liu
doaj   +1 more source

Regulatory Approaches to the Development Programme for Medicines Used to Treat Infectious Diseases

open access: yesРегуляторные исследования и экспертиза лекарственных средств, 2019
In February 2017 the World Health Organization first published the list of antibiotic-resistant «priority pathogens» — a catalogue of 12 species of bacteria that pose the greatest threat to human health.
I. V. Lysikova, O. I. Basova
doaj   +1 more source

Feasibility and Preliminary Efficacy of Integrative Neuromuscular Training for Childhood Cancer Survivors: A Pilot Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Survivors of childhood acute lymphoblastic leukemia (ALL) often exhibit early deficits in muscle and movement competence, which can compromise long‐term health. Integrative neuromuscular training (INT), a multifaceted approach combining fundamental movement activities with strength exercises, may help address these deficits during ...
Anna Maria Markarian   +7 more
wiley   +1 more source

The Role of Invasive Procedures in the Treatment of Complicated Gastrointestinal Graft‐Versus‐Host Disease in Pediatric Patients

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Gastrointestinal graft‐versus‐host disease (GI GVHD) following hematopoietic stem cell transplant is typically managed with medical therapy, but surgery and angioembolization may be warranted in selected cases with life‐threatening complications.
Gaia Brunetti   +12 more
wiley   +1 more source

A lightweight freezer management system for small laboratories [PDF]

open access: yes, 2012
In clinical studies, researchers must often maintain a freezer inventory of biosamples. Existing software packages, designed to track and manage freezer inventory, are not always suitable for small laboratories.

core   +1 more source

Ethnic Differences in the Association Between SOD2 rs4880 and Hepatotoxicity in Pediatric Acute Lymphoblastic Leukemia: A Report From the REDIAL Consortium

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Treatment‐associated hepatotoxicity (TAH) is a common complication of pediatric acute lymphoblastic leukemia (ALL) treatment, but genetic risk factors remain poorly understood. We evaluated the SOD2 rs4880 variant in 544 children with ALL at Texas Children's Hospital. After adjusting for demographic and clinical covariates, the rs4880 C allele
Emily J. Mason   +14 more
wiley   +1 more source

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