Results 151 to 160 of about 12,286,608 (353)

Anomaly Detection Algorithm for Real-World Data and Evidence in Clinical Research: Implementation, Evaluation, and Validation Study (Preprint)

, 2021
Vendula Churová, Roman Vyškovský, Kateřina Maršálová, David Kudláček, Daniel Schwarz   +4 more
openalex   +1 more source

Liquid biopsy epigenetics: establishing a molecular profile based on cell‐free DNA

Molecular Oncology, EarlyView.
Cell‐free DNA (cfDNA) fragments in plasma from cancer patients carry epigenetic signatures reflecting their cells of origin. These epigenetic features include DNA methylation, nucleosome modifications, and variations in fragmentation. This review describes the biological properties of each feature and explores optimal strategies for harnessing cfDNA ...
Christoffer Trier Maansson, Anders Lade Nielsen, Boe Sandahl Sorensen   +2 more
wiley   +1 more source

Role models and teachers: medical students perception of teaching-learning methods in clinical settings, a qualitative study from Sri Lanka.

, 2021
Vathsala Jayasuriya-Illesinghe, Ishra Nazeer, Lathika Athauda, Jennifer Perera   +3 more
openalex   +1 more source

Minimum clinically important difference of the Social Functioning in Dementia Scale (SF-DEM): cross-sectional study and Delphi survey [PDF]

, 2022
Tamara Levene, Gill Livingston, Sube Banerjee, Andrew Sommerlad   +3 more
openalex   +1 more source

Intein‐based modular chimeric antigen receptor platform for specific CD19/CD20 co‐targeting

Molecular Oncology, EarlyView.
CARtein is a modular CAR platform that uses split inteins to splice antigen‐recognition modules onto a universal signaling backbone, enabling precise, scarless assembly without re‐engineering signaling domains. Deployed here against CD19 and CD20 in B‐cell malignancies, the design supports flexible multi‐antigen targeting to boost T‐cell activation and
Pablo Gonzalez‐Garcia, Noelia Moares, Wenjie Yi‐He, Rosa Luna‐Espejo, Ricardo Fernandez‐Cisnal, Javier Ocaña‐Cuesta, Juan P. Muñoz‐Miranda, Antonio Gabucio, Cecilia M. Fernandez‐Ponce, Francisco Garcia‐Cozar   +9 more
wiley   +1 more source

Performance of the Cloud DX connected HealthKit Pulsewave in home blood pressure monitoring in a pregnant population: a clinical evaluation and user experience study [PDF]

Aniek Hofstede, Mayke Lomme, Stefanie Gosselink, J. van Drongelen   +3 more
openalex   +1 more source

WORLDS OF DIFFERENCE: ELDER MISTREATMENT PREVALANCE STUDIES AND CLINICAL PRACTICE [PDF]

, 2015

openalex   +1 more source

Occurrence of Type 1 Diabetes in a Patient Enrolled in an Immunotherapy Combination Phase 1 Clinical Trial: A Case Study

, 2021
Sheena Charles, Anna Poullard
openalex   +1 more source

Improving PARP inhibitor efficacy in bladder cancer without genetic BRCAness by combination with PLX51107

Molecular Oncology, EarlyView.
Clinical trials on PARP inhibitors in urothelial carcinoma (UC) showed limited efficacy and a lack of predictive biomarkers. We propose SLFN5, SLFN11, and OAS1 as UC‐specific response predictors. We suggest Talazoparib as the better PARP inhibitor for UC than Olaparib.
Jutta Schmitz, Anna L. Bartkowiak, Michael Rose, Nora Kolks, Patrick Petzsch, Vandana Solanki, Anne Stoffel, Bianca Faßbender, Leandra Lepping, Julka Volkamer, Karl Köhrer, Marc Seifert, Tokameh Mahmoudi, Tahlita C. M. Zuiverloon, Günter Niegisch, Michèle J. Hoffmann   +15 more
wiley   +1 more source

A CLINICAL STUDY OF MALIGNANT MAXILLARY SINUS TUMORS

, 2004
Masaru Tateda, Fumiaki Yoshida, Shigeru Saijo, Kiyoto Shiga, Junkichi Yokoyama   +4 more
openalex   +2 more sources