Results 181 to 190 of about 6,801,122 (248)

Adjunctive Eyelid Hygiene Improves Early Adaptation to Pediatric Orthokeratology: A Randomized Clinical Study. [PDF]

Eye Contact Lens
He M, Liu W, Liang J, Weng Y, Chen C, Zhang X.   +5 more
europepmc   +1 more source

Structural insights and therapeutic targets in Acinetobacter baumannii capsule biosynthesis

FEBS Letters, EarlyView.
Hypervirulent KL49 A. baumannii's capsular polysaccharide contains the nonulosonic acid 8‐epi‐Leg5,7Ac2, synthesized by epimerization via ElaA, ElaB, and ElaC. Crystal structures of ElaA, ElaB, and ElaC reveal their role in CMP‐Leg5,7Ac2 synthesis and regioselective C8 epimerization.
Woo Cheol Lee, Junho Jeong, Chae Yeong Lee, Hyunjoon Cho, Man Hwan Oh, Je Chul Lee, Jee‐Young Lee, Yangmee Kim   +7 more
wiley   +1 more source

Lactylation in cancer: molecular mechanisms and advances in clinical study. [PDF]

Mol Cancer
Li J, Miao C, Guo H, Lin M, Chen R, Peng J, Wang J, Tang C, Chen Z.   +8 more
europepmc   +1 more source

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Clinical Study on the Association Between Lipoprotein(a) Levels and Prognosis in Patients With Acute Ischemic Stroke. [PDF]

Brain Behav
Chen X, Zhang Y, Tang Y, Hu J, He X, Wu J.   +5 more
europepmc   +1 more source

Reconstructing enzyme evolution by protein engineering

FEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler, Markus R. Busch, Reinhard Sterner   +2 more
wiley   +1 more source

[THE CLINICAL STUDIES ON LINCOMYCIN].

The Journal of antibiotics. Ser. B, 1965
KAWAMORI, YUZO, TANAKA, SHUJI, NODA, SHUNSAKU, MISE, SADAHIRO, FURUDA, TOSHIFUSA   +4 more
openaire   +2 more sources

TMEM184A promotes progression and drug resistance in colorectal cancer: a bioinformatics and clinical study. [PDF]

Sci Rep
Bai X, Bai Z, Bu P, Liu R, Zhao G, Cui W, Cui Y, Xi Y.   +7 more
europepmc   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Retention of fluoride in the oral cavity: A randomized clinical study with nanoencapsulated fluoride toothpaste. [PDF]

J Clin Exp Dent
Avelino de Paiva MA, Moura HS, de Medeiros Souza MB, Júnior AA, Bezerra de Oliveira AF, Sampaio FC.   +5 more
europepmc   +1 more source