Results 141 to 150 of about 2,077,481 (282)
Attend and Diagnose: Clinical Time Series Analysis using Attention Models
, 2017 With widespread adoption of electronic health records, there is an increased emphasis for predictive models that can effectively deal with clinical time-series data.
Rajan, Deepta +3 more
core +1 more source
Advanced Functional Materials, EarlyView.PREdicting LNP In Vivo Efficacy (PRELIVE) framework enables the prediction of lipid nanoparticle (LNPs) organ‐specific delivery through dual modeling approaches. Composition‐based models using formulation parameters and protein corona‐based models using biological fingerprints both achieve high predictive accuracy across multiple organs.
Belal I. Hanafy +3 more
wiley +1 more source
Advanced Functional Materials, EarlyView.A UV‐triggered injectable dual‐network hydrogel is reported as the first application of bletilla striata polysaccharide (BSP) in osteochondral repair. By integrating methacrylamide‐modified BSP and nitrobenzaldehyde‐functionalized hyaluronic acid, the system achieves immunomodulation, mechanical reinforcement, and dynamic tissue adhesion, thereby ...
Jiaming Cui +10 more
wiley +1 more source
Characteristics and Outcomes of Pediatric Retinal Detachment Surgery at a Tertiary Referral Center
Journal of Ophthalmic & Vision Research, 2014 Purpose: To report the clinical features, and anatomic and visual outcomes of pediatric retinal detachment (RD) surgery at a tertiary referral center in Southern Iran.
Mansour Rahimi +2 more
doaj
Drug‐Free Thrombolysis Mediated by Physically Activated Micro/Nanoparticles
Advanced Functional Materials, EarlyView.Overview of particle‐mediated thrombolytic effects (thermal, mechanical, and chemical) and their activating physical stimuli (light, ultrasound, and magnetic field) in drug‐free thrombolysis. ABSTRACT Thrombus‐associated disorders rank among the world's leading causes of death, with ischemic heart disease and stroke as the main contributors.
Pierre Sarfati +2 more
wiley +1 more source
Advanced Functional Materials, EarlyView.MagPiezo enables wireless activation of endogenous Piezo1 channels without genetic modification using 19 nm magnetic nanoparticles and low‐intensity magnetic fields. It generates torque forces at the piconewton scale to trigger mechanotransduction in endothelial cells, standing as a novel platform to interrogate and manipulate Piezo1 activity in vitro.
Susel Del Sol‐Fernández +7 more
wiley +1 more source
From mechanisms of heart failure to clinical heart success
Disease Models & Mechanisms, 2023 Jeroen Bakkers +3 more
doaj +1 more source
Advanced Healthcare Materials, EarlyView.We characterized the distribution of cargo proteins associated with extracellular vesicles using various exogenous loading methods. In all cases, single‐particle analysis revealed that the distribution of protein content per EV is heterogeneous, following an exponential decay function.
Karl Normak +6 more
wiley +1 more source
Advanced Healthcare Materials, EarlyView.The repair and regeneration of brain tissue faces both biological and technical challenges. Injectable bioscaffolds offer new opportunities to stimulate tissue regrowth in the brain by recruiting neural stem cells. Here, the translational issues are reviewed that need to be address to advance this promising new therapeutic approach from the bench to ...
Michel Modo, Alena Kisel
wiley +1 more source
Advanced Healthcare Materials, EarlyView.This study introduces an innovative approach to treating intervertebral disc degeneration using ultrasound‐triggered in situ hydrogel formation. Proof‐of‐concept experiments using optimized biomaterial and ultrasound parameters demonstrate partial restoration of biomechanical function and successful integration into degenerated disc tissue, offering a ...
Veerle A. Brans +11 more
wiley +1 more source