Results 181 to 190 of about 2,077,481 (282)

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

P-15 Peptide Enhanced Bone Graft in Transforaminal Lumbar Interbody Fusion: A Randomized, Controlled, Investigational Device Exemption Study Demonstrating Improved Composite Clinical Success. [PDF]

Spine (Phila Pa 1976)
Harrop JS, O'Toole JE, Steinmetz MP, Sasso RC, Chaput CD, Strenge KB, Maislin G, Mullin JP, Freeman TB, Guanciale A, Lantner H, Janssen ME, Schwartz DG, Small JM, Hsu WK, Arnold PM.   +15 more
europepmc   +1 more source

Haematological risk factors predicting clinical success in transarterial embolisation for acute gastrointestinal bleeding. [PDF]

Br J Radiol, 2023
Delf J, Ramachandran S, Martin CA, Vadera S, Mustafa S, Waters K, Saeed A, Adair W, Glasby M, Kandiyil N.   +9 more
europepmc   +1 more source

Giving It a Twist: One‐Step Fabrication of Aligned Biomimetic Yarn Scaffolds via Rotational Melt Electrofibrillation

Advanced Healthcare Materials, EarlyView.
Due to its multifunctionality, replicating the fibrillar and supramolecular architecture of Collagen I is gaining increasing priority in regenerative medicine. Using rotational Melt Electrofibrillation, we present a powerful method to accurately mimic the ultrastructure of Collagen with polycaprolactone, enabling the one‐step fabrication of three ...
Zan Lamberger, Vivien Priebe, Philipp Stahlhut, Kristina Andelovic, Girish Pattappa, Denitsa Docheva, Sven Heilig, Heike M. Hermanns, Taufiq Ahmad, Jürgen Groll, Gregor Lang, Matthias Ryma   +11 more
wiley   +1 more source

Survival and clinical success of endovascular intervention in patients with Budd-Chiari syndrome: A systematic review. [PDF]

J Clin Imaging Sci, 2023
Mukhiya G, Jiao D, Han X, Zhou X, Pokhrel G.   +4 more
europepmc   +1 more source

Triazine‐Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering

Advanced Healthcare Materials, EarlyView.
Novel photo‐clickable triazine‐trione thermosets can be shaped and cured under mild conditions, including room and physiological temperatures. These materials are biocompatible and support osteogenic differentiation of bone marrow–derived mesenchymal stem cells on their surface.
Åshild Johansen, Shuntaro Yamada, Daniel J. Hutchinson, Mohammed A. Yassin, Samih Mohamed‐Ahmed, Cecilie Gjerde, Michael Malkoch, Kamal Mustafa   +7 more
wiley   +1 more source

Development of Co-Amorphous Systems for Inhalation Therapy-Part 1: From Model Prediction to Clinical Success. [PDF]

Pharmaceutics
Fröhlich E, Bordoni A, Mohsenzada N, Mitsche S, Schröttner H, Zellnitz-Neugebauer S.   +5 more
europepmc   +1 more source

Long-term evaluation of clinical success and safety of omadacycline in nontuberculous mycobacteria infections: a retrospective, multicenter cohort of real-world health outcomes. [PDF]

Antimicrob Agents Chemother, 2023
El Ghali A, Morrisette T, Alosaimy S, Lucas K, Tupayachi-Ortiz MG, Vemula R, Wadle C, Philley JV, Mejia-Chew C, Hamad Y, Stevens RW, Zeuli JD, Webb AJ, Fiske CT, Simonyan A, Cimino CL, Mammadova M, Umana VE, Hasbun R, Butt S, Molina KC, Thomas M, Kaip EA, Bouchard J, Gore TW, Howard C, Cabanilla MG, Holger DJ, Frens JJ, Barger M, Ong A, Cohen KA, Rybak MJ.   +32 more
europepmc   +1 more source

Characterization of an Injectable Poly(vinyl alcohol)‐gelatin Hydrogel for Growth Factor Delivery in an Orthopedic Application

Advanced Healthcare Materials, EarlyView.
This work introduces photo‐crosslinkable tyraminated poly(vinyl alcohol)‐gelatin (PVA‐GT) hydrogels as tunable injectable platforms for tissue engineering and growth factor delivery applications. This schematic illustrates the two developed hydrogel formulations and the experimental workflow used to evaluate their physico‐chemical properties in vitro ...
Alessia Longoni, Gretel S. Major, Sam Arnold, Samuel Tomkins, Eugenia Spessot, Scott Loeffler, Kieran Lau, Richard Tan, Jessica Harte, Roslyn Kemp, Tess Reynolds, Jelena Rnjak‐Kovacina, Gary J. Hooper, Tim B. F. Woodfield, David C. Kieser, Khoon S. Lim   +15 more
wiley   +1 more source

Functional and Mechanistic Explanation for the Unique Clinical Success of the Glucokinase Activator Dorzagliatin in the Treatment of Type 2 Diabetes. [PDF]

Diabetes
Roman J, Yuan Y, Xu Y, Zhu Q, Wu S, Zhao F, Zhou X, Meng S, Han D, Sharp K, Chen L, Li C, Doliba NM.   +12 more
europepmc   +1 more source