Results 231 to 240 of about 3,600,128 (335)
TICTAC: target illumination clinical trial analytics with cheminformatics. [PDF]
Front BioinformAbok JI, Edwards JS, Yang JJ.
europepmc +1 more source
Molecular Oncology, EarlyView.AZD9291 has shown promise in targeted cancer therapy but is limited by resistance. In this study, we employed metabolic labeling and LC–MS/MS to profile time‐resolved nascent protein perturbations, allowing dynamic tracking of drug‐responsive proteins. We demonstrated that increased NNMT expression is associated with drug resistance, highlighting NNMT ...
Zhanwu Hou +5 more
wiley +1 more source
Inflammatory Exposure and Depression in Older Adults With Insomnia: A Randomized Clinical Trial.
JAMA PsychiatryIrwin MR +8 more
europepmc +1 more source
Clinical Trial Sites and Malaria Incidence Mismatch. [PDF]
Am J Trop Med HygBrahmbhatt S, Jain M, Kshirsagar N.
europepmc +1 more source
Molecular Oncology, EarlyView.Single‐cell transcriptomics of prostate cancer patient‐derived xenografts reveals distinct features of neuroendocrine (NE) subtypes. Tumours with focal NE differentiation (NED) share transcriptional programmes with adenocarcinoma, differing from large and small cell neuroendocrine prostate cancer (NEPC). Our work defines the molecular landscape of NEPC,
Rosalia Quezada Urban +12 more
wiley +1 more source
CLINICAL ASSESSMENT OF ANALGESIC DRUGS (4) INTRAVENOUS TRIAL
, 1964 A.H.B. MASSON
openalex +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source