Results 91 to 100 of about 10,015 (184)

Comparison of the Efficacy and Safety of Sutureless Technique Versus Conventional Surgery in the Initial Treatment of Total Anomalous Pulmonary Venous Connection: A Systematic Review and Meta‐Analysis

Pulmonary Circulation, Volume 16, Issue 1, January 2026.
ABSTRACT Total anomalous pulmonary venous connection (TAPVC) is a rare but life‐threatening congenital heart defect that requires surgical correction. The sutureless technique has been developed as an alternative to conventional repair to minimize postoperative complications.
Lei Shen, Nan Ding, Haiju Liu, Hanlu Yi, Jinrui Zhang, Gejingwa Zhao, Zhiqiang Li   +6 more
wiley   +1 more source

Defective DNA repair mechanisms in prostate cancer: impact of olaparib [PDF]

, 2017
The field of prostate oncology has continued to change dramatically. It has truly become a field that is intensely linked to molecular genetic alterations, especially DNA-repair defects.
De Felice, Francesca, Marampon, Francesco, Marchetti, Claudia, Musella, Angela, Tombolini, Vincenzo   +4 more
core   +2 more sources

Integration of a WASH Component in the Standard National Protocol for Treatment of Severe Acute Malnutrition in Children Aged 6–59 Months in Northern Senegal—A Costing Study

Maternal &Child Nutrition, Volume 22, Issue 1, January 2026.
This study provides the first cost analysis of integrating a WASH kit into outpatient SAM treatment in Senegal, highlighting key cost drivers and potential efficiencies for scale‐up. Findings offer practical insights for planning and budgeting integrated WASH‐nutrition interventions in similar settings.
Bibata Wassonguema, Maily Lê‐Lacanette, Laura Braun, Matar Ba, Françoise Siroma, Albert Emile Cabo, Antonio Vargas Brizuela, Moustapha Seye, Jean Lapègue, Alexandre Devort, Oliver Cumming, Dieynaba S. N'Diaye   +11 more
wiley   +1 more source

Sacubitril and valsartan fixed combination to reduce heart failure events in post-acute myocardial infarction patients [PDF]

, 2017
Heart failure is a term used to define a constellation of symptoms and signs that are commonly attributed to the inability of the heart to produce a cardiac output that meets the demands of the body. It remains a deadly disease, affecting between 1-2% of
Lang, C. C., Zaid Iskandar, M.
core   +2 more sources

Butyrate‐Mediated Upregulation of Insulin Pathway Gene Expression Suggests Potential Antidiabetic Effects

Drug Development Research, Volume 86, Issue 8, December 2025.
ABSTRACT Type 2 diabetes (T2D) is a major cause of morbidity in developed countries and involves insulin resistance, a failure to correctly respond to insulin. Numerous studies in rodent T2D models suggested that the short‐chain fatty acid butyrate, produced by gut microbiota species through fermentation of dietary fibers, improves T2D symptoms.
Elad Shapira, Irena Voinsky, Hana Klin, David Gurwitz   +3 more
wiley   +1 more source

Quantitative d-dimer level and anticoagulant therapy in idiopathic intracranial hypertension

The Egyptian Journal of Neurology, Psychiatry and Neurosurgery, 2019
Background Idiopathic intracranial hypertension (IIH) is a syndrome characterized by elevated intracranial pressure (ICP) of unknown etiology Aim of the work The aim of this research is to study the quantitative d-dimer level and the role of ...
Hala Shaheen, Sayed Sobhy, Sherine El Mously, Mohamed El Khatib, Amany Hamdy   +4 more
doaj   +1 more source

How Psychiatry Journals Support the Unbiased Translation of Clinical Research. A Cross-Sectional Study of Editorial Policies [PDF]

, 2013
Introduction: Reporting guidelines (e. g. CONSORT) have been developed as tools to improve quality and reduce bias in reporting research findings. Trial registration has been recommended for countering selective publication.
Knüppel, Hannes, Meerpohl, Jörg J., Metz, Courtney, Strech, Daniel   +3 more
core   +3 more sources

The effect of modulated electro-hyperthermia on local disease control in HIV-positive and -negative cervical cancer women in South Africa : early results from a phase III randomised controlled trial [PDF]

, 2019
Background : The global burden of cervical cancer remains high with the highest morbidity and mortality rates reported in developing countries. Hyperthermia as a chemo- and radiosensitiser has shown to improve treatment outcomes.
Ayeni, Olusegun Akinwale, Baeyens, Ans, Kotzen, Jeffrey Allan, Minnaar, Carrie Anne, Naidoo, Thanushree, Sharma, Vinay, Tunmer, Mariza, Vangu, Mboyo-Di-Tamba   +7 more
core   +2 more sources

Implementation of Metformin Therapy to Ease Decline of Kidney Function in Polycystic Kidney Disease (IMPEDE-PKD): study protocol for a phase III, multi-centre, randomized, placebo-controlled trial evaluating the long-term efficacy of metformin in slowing the rate of kidney function decline in patients with autosomal dominant polycystic kidney disease

Trials
Background Autosomal dominant polycystic kidney disease (ADPKD) is the fourth most common reason for commencement of dialysis globally. There is an urgent need for treatments to slow the loss of kidney function and prevent complications in people with ...
Kitty St Pierre, Ragada El-Damanawi, David W. Johnson, Carmel M. Hawley, Andrea K. Viecelli, Vivekanand Jha, Suetonia C. Green, Loreto Gesualdo, Charani Kiriwandeniya, Pushparaj Velayudham, Liza A. Vergara, Gabor Mihala, Misa Matsuyama, Peta-Ann Paul Brent, Andrew J. Mallett, IMPEDE-PKD Global Steering Committee (see Appendix)   +15 more
doaj   +1 more source

A phase 1/2, open-label study evaluating twice-daily administration of momelotinib in myelofibrosis

Haematologica, 2017
Momelotinib, a small-molecule inhibitor of Janus kinase 1 and Janus kinase 2, has demonstrated efficacy in myelofibrosis patients with 300 mg, once-daily dosing.
Vikas Gupta, Ruben A. Mesa, Michael W.N. Deininger, Candido E. Rivera, Shireen Sirhan, Carrie Baker Brachmann, Helen Collins, Jun Kawashima, Yan Xin, Srdan Verstovsek   +9 more
doaj   +1 more source