Results 31 to 40 of about 10,015 (184)

Hemorrhage in patients with polycythemia vera receiving aspirin with an anticoagulant: a prospective, observational study

Haematologica, 2021
Polycythemia vera (PV) is associated with increased risk of thrombosis and hemorrhage. Aspirin, recommended for primary thromboprophylaxis, is often combined with anticoagulants during management of acute thrombotic events.
Jeffrey I. Zwicker, Dilan Paranagama, David S. Lessen, Philomena M. Colucci, Michael R. Grunwald   +4 more
doaj   +1 more source

The Rescue on Reperfusion Damage in Cerebral Infarction by Nelonemdaz (RODIN) Trial: Protocol for a Double-Blinded Clinical Trial of Nelonemdaz in Patients with Hyperacute Ischemic Stroke and Endovascular Thrombectomy [PDF]

Journal of Stroke, 2023
Background and Purpose Nelonemdaz (Neu2000) has both selective antagonism against 2B subunit of N-methyl-D-aspartate receptor and antioxidant activity.
Jin Soo Lee, Ji Sung Lee, Byoung Joo Gwag, Dennis W. Choi, Chun San An, Hyun Goo Kang, Tae-Jin Song, Seong Hwan Ahn, Chang Hun Kim, Dong-Ick Shin, Sun U. Kwon   +10 more
doaj   +1 more source

Quality and Publication of Emergency Medicine Trials Registered in ClinicalTrials.gov [PDF]

, 2020
Introduction: Promoting emergency medicine (EM) clinical trials research remains a priority. To characterize the status of clinical EM research, this study assessed trial quality, funding source, and publication of EM clinical trials and compared EM and ...
Calvocoressi, Lisa, Carroll, Megan, Dziura, James, Johnson, Benjamin, Post, Lori, Reynolds, Jesse, Vaca, Federico E., Warzoha, Meghan M.   +7 more
core  

Novel anti-tumour necrosis factor receptor-1 (TNFR1) domain antibody prevents pulmonary inflammation in experimental acute lung injury. [PDF]

, 2018
BACKGROUND: Tumour necrosis factor alpha (TNF-α) is a pleiotropic cytokine with both injurious and protective functions, which are thought to diverge at the level of its two cell surface receptors, TNFR1 and TNFR2.

core   +2 more sources

Long term post PrePex male circumcision outcomes in an urban population in Uganda: a cohort study

BMC Research Notes, 2017
Objective The objective of this study was to determine the long term adverse events profile at least a year after safe male circumcision. Results A cohort study, investigating patients who had undergone a non surgical circumcision procedure called Prepex.
M. Galukande, F. Nakaggwa, E. Busisa, D. Sekavuga Bbaale, T. Nagaddya, A. Coutinho   +5 more
doaj   +1 more source

Sublingual allergen immunotherapy with a liquid birch pollen product in patients with seasonal allergic rhinoconjunctivitis with or without asthma [PDF]

, 2019
Background: Sublingual allergen immunotherapy (SLIT) has been demonstrated to be both clinically efficacious and safe. However, in line with the current regulatory guidance from the European Medicines Agency, allergen immunotherapy (AIT) products must ...
Bachert, Claus, Boot, Johan D, de Kam, Pieter-Jan, Džupinová, Mária, Klimek, Ludger, Kuna, Piotr, Opstelten, Dirk Jan E, Panzner, Petr, Pfaar, Oliver, van Nimwegen, Maroesja J, Yu, Donghui   +10 more
core   +2 more sources

Integrative prognostic models predict long-term survival after immunochemotherapy in chronic lymphocytic leukemia patients

Haematologica, 2021
Chemoimmunotherapy with fludarabine, cyclophosphamide and rituximab (FCR) can induce long-term remissions in patients with chronic lymphocytic leukemia.
Johannes Bloehdorn, Julia Krzykalla, Karlheinz Holzmann, Andreas Gerhardinger, Billy Michael Chelliah Jebaraj, Jasmin Bahlo, Kathryn Humphrey, Eugen Tausch, Sandra Robrecht, Daniel Mertens, Christof Schneider, Kirsten Fischer, Michael Hallek, Hartmut Döhner, Axel Benner, Stephan Stilgenbauer   +15 more
doaj   +1 more source

Trial discontinuation: lessons for future trial design? [PDF]

, 2012
Background: The current therapeutic arsenal still does not fulfill the therapeutic needs of inflammatory bowel disease patients. Although new drugs are constantly being developed, many will never reach the market.
Haar, C.J. (Colin) de, Nuij, V.J.A.A. (Veerle), Woude, C.J. (Janneke) van der   +2 more
core   +1 more source

Haploidentical CD7 CAR T-cells induced remission in a patient with TP53 mutated relapsed and refractory early T-cell precursor lymphoblastic leukemia/lymphoma

Biomarker Research, 2022
Patients with relapsed/refractory early T-cell precursor lymphoblastic leukemia/lymphoma (ETP-ALL/LBL) respond poorly to traditional therapy and have dismal prognosis.
Hai-ping Dai, Wei Cui, Qing-ya Cui, Wen-juan Zhu, Hui-min Meng, Min-qing Zhu, Xia-ming Zhu, Lin Yang, De-pei Wu, Xiao-wen Tang   +9 more
doaj   +1 more source

Impact of mindfulness training and yoga on injury and pain-related impairment: a group randomized trial in basic combat training

Frontiers in Psychology, 2023
IntroductionService members are at risk for pain-related difficulties in functioning and physical injury. Previous studies suggest that mindfulness training (MT) and yoga may prevent these outcomes.
Carl D. Smith, Ian A. Gutierrez, Thomas H. Nassif, Kimberley L. Jordan, Kathryn M. Taylor, Amishi P. Jha, Amy B. Adler   +6 more
doaj   +1 more source