Results 51 to 60 of about 10,563 (168)

Clinical Evaluation of Risankizumab-rzaa in the Treatment of Plaque Psoriasis. [PDF]

, 2020
Risankizumab-rzaa (Skyrizi®; AbbVie) is a humanized IgG monoclonal antibody directed against interleukin-23p19 (IL-23p19) indicated for the treatment of moderate-to-severe psoriasis in adults who are candidates for systemic therapy or phototherapy.
Liao, Wilson, Myers, Bridget, Reddy, Vidhatha, Yang, Eric J   +3 more
core   +1 more source

External validity of randomized controlled trials on Alzheimer's disease: the biases of frailty and biological aging [PDF]

, 2017
To date, the external validity of randomized controlled trials (RCTs) on Alzheimer's disease (AD) has been assessed only considering monodimensional variables.
Alessandro Trebbastoni, Carlo de Lena, Fabrizia D’Antonio, Federica Quarata, Giuseppe Bruno, Marco Canevelli, Matteo Cesari, Matteo Cesari   +7 more
core   +3 more sources

Mapping Evidence on Care Interventions for People Living With Motor Neurone Disease: A Protocol for a Living Evidence and Gap Map

Clinical and Public Health Guidelines, Volume 3, Issue 2, April 2026.
ABSTRACT Objective To map the available evidence informing the care and management of people living with motor neurone disease (MND), including evidence pertaining to carers, asymptomatic genetic carriers, family, friends and healthcare professionals caring for people with MND.
Danielle Pollock, Cindy Stern, Melissa Bond, Timothy Hugh Barker, Sabira Hasanoff, Grace Holland, Ines Semendric, Anna Fragkoudi, Nipun Shrestha, Sebastian Cole Facchin‐Young, Abigail Molly Day‐Sharman, Lemma Negesa Bulto, Lara Stollery, Sitasma Sharma, Camille Schubert, Lynne Giles, Jay Beasley‐Hall, Tracy Merlin, Julie Labra, Steve Vucic, Taryn Hunt, Zachary Munn   +21 more
wiley   +1 more source

Use of the Hedgehog signaling pathway inhibitor in the treatment of recurrent locally advanced and metastatic basal cell skin cancer

Опухоли головы и шеи, 2020
The study objective is to provide data on the use of the Hedgehog signaling pathway inhibitor (vismodegib) in the treatment of recurrent locally advanced and metastatic basal cell skin cancer at the N. N.
Z. A.-G. Radzhabova, M. A. Kotov, Z. S. Bekyasheva, M. A. Radzhabova, E. V. Levchenko   +4 more
doaj   +1 more source

Impact of mindfulness training and yoga on injury and pain-related impairment: a group randomized trial in basic combat training

Frontiers in Psychology, 2023
IntroductionService members are at risk for pain-related difficulties in functioning and physical injury. Previous studies suggest that mindfulness training (MT) and yoga may prevent these outcomes.
Carl D. Smith, Ian A. Gutierrez, Thomas H. Nassif, Kimberley L. Jordan, Kathryn M. Taylor, Amishi P. Jha, Amy B. Adler   +6 more
doaj   +1 more source

Health-related preferences of older patients with multimorbidity: the protocol for an evidence map [PDF]

, 2019
Introduction: Interaction of conditions and treatments, complicated care needs and substantial treatment burden make patient–physician encounters involving multimorbid older patients highly complex.
Blom, Jeanet, Gerlach, Ferdinand M, González-González, Ana Isabel, Hoffmann, Tammy, Meerpohl, Joerg J, Muth, Christiane, Nguyen, Truc Sophia, Nothacker, Julia, Röttger, Kristian, Schmucker, Christine, Straus, Sharon E, van den Akker, Marjan, Wegwarth, Odette   +12 more
core   +1 more source

Real‐World Edoxaban Concentrations in Older Patients Receiving Reduced‐Dose Regimens

Clinical Pharmacology &Therapeutics, Volume 119, Issue 3, Page 688-695, March 2026.
Real‐world edoxaban concentrations in older patients receiving reduced‐dose regimens. Low trough concentrations (< 12 ng/mL) were associated with an increased risk of thromboembolism. Among patients meeting the ELDERCARE‐AF criteria, low drug levels were more frequent with the 15 mg regimen than with the 30 mg regimen.
Sung‐Chun Tang, Shin‐Yi Lin, Chih‐Hao Chen, Yen‐Bin Liu, Li‐Ting Ho, Ching‐Hua Kuo, Yu‐Fong Peng, Chih‐Fen Huang, Jiann‐Shing Jeng   +8 more
wiley   +1 more source

Oral HDAC inhibitor tucidinostat in patients with relapsed or refractory peripheral T-cell lymphoma: phase IIb results

Haematologica, 2022
Tucidinostat (formerly known as chidamide) is an orally available, novel benzamide class of histone deacetylase (HDAC) inhibitor that selectively blocks class I and class IIb HDAC.
Shinya Rai, Won Seog Kim, Kiyoshi Ando, Ilseung Choi, Koji Izutsu, Norifumi Tsukamoto, Masahiro Yokoyama, Kunihiro Tsukasaki, Junya Kuroda, Jun Ando, Michihiro Hidaka, Youngil Koh, Hirohiko Shibayama, Toshiki Uchida, Deok Hwan Yang, Kenji Ishitsuka, Kenichi Ishizawa, Jin Seok Kim, Hong Ghi Lee, Hironobu Minami, Hyeon Seok Eom, Mitsutoshi Kurosawa, Jae Hoon Lee, Jong Seok Lee, Won Sik Lee, Hirokazu Nagai, Takero Shindo, Dok Hyun Yoon, Shinichiro Yoshida, Mireille Gillings, Hiroshi Onogi, Kensei Tobinai   +31 more
doaj   +1 more source

Assessing the consequences of gestational diabetes mellitus on offspring's cardiovascular health: MySweetHeart Cohort study protocol, Switzerland. [PDF]

, 2017
Gestational diabetes mellitus (GDM) is a state of glucose intolerance with onset during pregnancy. GDM carries prenatal and perinatal risks as well as long-term risks for the mother and her child.
Bovet, P., Chiolero, A., Di Bernardo, S., Epure, A.M., Estoppey Younes, S., Mivelaz, Y., Sekarski, N., Simeoni, U., Vial, Y.   +8 more
core   +1 more source

Resting Cerebrovascular Haemodynamics and Dynamic Assessment of Cerebrovascular Function in Polycystic Ovary Syndrome

Clinical Endocrinology, Volume 104, Issue 3, Page 245-254, March 2026.
ABSTRACT Objective Despite an increased cerebrovascular disease risk, the impact of Polycystic Ovary Syndrome (PCOS) on cerebrovascular haemodynamics and function is unknown. This study characterised cerebrovascular haemodynamics and function in women with PCOS versus healthy controls. Design Case‐control study.
Cory T. Richards, Thomas D. Griffiths, Zoe H. Adams, Melissa E. Wright, Saajan Davies, Jack S. Talbot, Lauren Broad‐Thomas, Diego García Esteban, Jessica J. Steventon, Patrice Brassard, Kevin Murphy, Philip E. James, D. Aled Rees, Rachel N. Lord   +13 more
wiley   +1 more source