Results 51 to 60 of about 10,015 (184)

Study protocol for THINK : a multinational open-label phase I study to assess the safety and clinical activity of multiple administrations of NKR-2 in patients with different metastatic tumour types [PDF]

open access: yes, 2017
Introduction: NKR-2 are autologous T cells genetically modified to express a chimeric antigen receptor (CAR) comprising a fusion of the natural killer group 2D (NKG2D) receptor with the CD3 zeta signalling domain, which associates with the adaptor ...
Aftimos, Philippe   +15 more
core   +1 more source

Validation of visual analog scales of mood and anxiety at the workplace.

open access: yesPLoS ONE
The Hospital Anxiety and Depression Scale (HADS) is commonly used to detect depressive or anxious states, but its 14-item questionnaire is time-consuming. Visual analog scales (VAS) are easy to use and quick to implement.
Frédéric Dutheil   +11 more
doaj   +1 more source

AGuIX® from bench to bedside-Transfer of an ultrasmall theranostic gadolinium-based nanoparticle to clinical medicine [PDF]

open access: yes, 2018
International audienceAGuIX® are sub-5 nm nanoparticles made of a polysiloxane matrix and gadolinium chelates. This nanoparticle has been recently accepted in clinical trials in association with radiotherapy.
Abadjian, Marie-Caline   +47 more
core   +3 more sources

How Effective Is Vitamin C for Gingival Depigmentation? A Scoping Review

open access: yesClinical and Experimental Dental Research, Volume 12, Issue 2, April 2026.
ABSTRACT Objectives Excessive gingival pigmentation can be treated by surgically removing the pigmented gingival tissue with a scalpel, bur, LASER, electrocautery, cryotherapy, chemical peeling, or masking with free gingival grafts. Recently, vitamin C (ascorbic acid), in gel, powder, or liquid has been used alone or as an adjunct to micro‐needling or ...
Shubhankar Mehrotra   +4 more
wiley   +1 more source

Immunochemotherapy plus lenalidomide for high-risk mantle cell lymphoma with measurable residual disease evaluation

open access: yesHaematologica, 2023
Chemoimmunotherapy followed by consolidative high-dose therapy with autologous stem cell rescue was a standard upfront treatment for fit patients with mantle cell lymphoma (MCL) in first remission; however, treatment paradigms are evolving in the era of
Zachary D. Epstein-Peterson   +23 more
doaj   +1 more source

Cutaneous adverse reaction during lithium treatment: a case report and updated systematic review with meta-analysis [PDF]

open access: yes, 2017
OBJECTIVES: To present a new case of adverse cutaneous reaction during lithium treatment and to update the systematic review and meta-analysis of the incidence of this adverse reaction.
Manchia, Mirko   +5 more
core   +2 more sources

Mapping Evidence on Care Interventions for People Living With Motor Neurone Disease: A Protocol for a Living Evidence and Gap Map

open access: yesClinical and Public Health Guidelines, Volume 3, Issue 2, April 2026.
ABSTRACT Objective To map the available evidence informing the care and management of people living with motor neurone disease (MND), including evidence pertaining to carers, asymptomatic genetic carriers, family, friends and healthcare professionals caring for people with MND.
Danielle Pollock   +21 more
wiley   +1 more source

External validity of randomized controlled trials on Alzheimer's disease: the biases of frailty and biological aging [PDF]

open access: yes, 2017
To date, the external validity of randomized controlled trials (RCTs) on Alzheimer's disease (AD) has been assessed only considering monodimensional variables.
Alessandro Trebbastoni   +7 more
core   +3 more sources

Post Hoc Subgroup Analysis of Clinical Outcomes in Patients With High‐Risk Metastatic Hormone‐Naïve Prostate Cancer: Results From a 3‐Year Interim Analysis of the J‐ROCK Study

open access: yesThe Prostate, Volume 86, Issue 5, Page 599-608, April 2026.
ABSTRACT Introduction In real‐world practice in Japan, standard treatment for metastatic hormone‐naïve prostate cancer (mHNPC) is androgen deprivation therapy (ADT), administered as monotherapy, combined androgen blockade (CAB), ADT plus androgen receptor pathway inhibitors (ARPIs), or ADT plus docetaxel.
Atsushi Mizokami   +14 more
wiley   +1 more source

Eficacia terapéutica y eventos adversos de tratamientos para malaria vivax y malaria falciparum en gestantes en las regiones de Urabá y Alto San Jorge, Colombia, 2008-2011

open access: yesRevista Colombiana de Obstetricia y Ginecología, 2013
Objetivo: evaluar, con el protocolo de la Organización Mundial de la Salud (OMS) de 1998, la respuesta terapéutica antimalárica (RTA) y los eventos adversos (EA) en cuatro esquemas de tratamiento antiplasmodial en gestantes colombianas, con diagnóstico ...
Jaime Carmona-Fonseca   +2 more
doaj   +1 more source

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