Results 41 to 50 of about 5,457,303 (315)

Risk and clinicopathological features of osteosarcoma metastasis to the lung: A population-based study

Journal of Bone Oncology, 2019
Background Osteosarcoma is the most common primary sarcoma of the bone. Lung osteosarcoma metastases at diagnosis have a significantly poor prognosis, even when surgery plus chemotherapy are performed.
Xiaoyi Huang, Jian Zhao, Jinyi Bai, Hua Shen, Bingbing Zhang, Lulu Deng, Chen Sun, Yanfang Liu, Jing Zhang, Jian-ming Zheng   +9 more
semanticscholar   +1 more source

Oral–maxillofacial and cervical schwannomas: a retrospective cohort analysis with a rare intraosseous case

BMC Oral Health
Objective To evaluate the clinical, pathological, and immunohistochemical characteristics of schwannomas (SCHs) in the oral, maxillofacial, and cervical regions to provide a reference for their diagnosis and clinical management.
Xiaomin Hu, Dongxiang Wang, Zhenglong Tang   +2 more
doaj   +1 more source

Keratin 19 as a prognostic marker and contributing factor of metastasis and chemoresistance in high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Keratin 19 (KRT19) is overexpressed in high‐grade serous ovarian cancer with high levels of Kallikrein‐related peptidases (KLK) 4–7 and is associated with poor survival. In vivo analyses demonstrate that elevated KRT19 increases peritoneal tumour burden.
Sophia Bielesch, Isabel Vogel, Sina Nokodian, Johanna Moeller, Antonia Blechschmidt, Vicky Hecht, Vanessa Kuentzel, Katharina Thiedig, Melissa Schwab, Oliver Schilling, Holger Bronger, Marion Kiechle, Viktor Magdolen, Tobias Dreyer   +13 more
wiley   +1 more source

Frequency and clinicopathological features of metastasis to liver, lung, bone, and brain from gastric cancer: A SEER‐based study

Cancer Medicine, 2018
The hematogenous metastatic pattern of gastric cancer (GC) was not fully explored. Here we analyzed the frequency and clinicopathological features of metastasis to liver, lung, bone, and brain from GC patients.
M. Qiu, Si-Mei Shi, Zhan-hong Chen, Hong-En Yu, Hui Sheng, Ying Jin, Deshen Wang, Fenghua Wang, Yu-hong Li, D. Xie, Zhiwei Zhou, Da-jun Yang, R. Xu   +12 more
semanticscholar   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Hepatocellular carcinoma – clinicopathological characteristics, survival, and expression of various histologic molecular markers

Polish Journal of Pathology, 2020
The aim of this study was to make a clinical characterisation of patients with hepatocellular carcinoma and to investigate the expression of a set of molecular markers in patients from the Republic of North Macedonia.
Dafina Nikolova, Viktorija Ivanova, Magdalena Dimitrova, Rubens Jovanovik, Slavica Kunovska, Nikola Orovcanec, Gordana Petrushevska, Vesna Janevska   +7 more
doaj   +1 more source

Clinicopathological Features Combined With Immune Infiltration Could Well Distinguish Outcomes in Stage II and Stage III Colorectal Cancer: A Retrospective Study

Frontiers in Oncology, 2021
BackgroundThe Immunoscore predicts prognosis in patients with colorectal cancer (CRC). However, a few studies have incorporated the Immunoscore into the construction of comprehensive prognostic models in CRC, especially stage II CRC.
Jiazi Ren, Linfeng Xu, Linfeng Xu, Siyu Zhou, Jian Ouyang, Weiqiang You, Nengquan Sheng, Li Yan, Du Peng, Lu Xie, Zhigang Wang   +10 more
doaj   +1 more source

Clinicopathological features of dermatofibrosarcoma protuberans

Oncology Letters, 2015
Dermatofibrosarcoma protuberans (DFSP) is a superficial cutaneous tumor of low malignant potential characterized by a high rate of local recurrence. The histopathological appearance shows uniform spindle neoplastic cells arranged in a predominantly storiform pattern, typically with positive staining for cluster of differentiation (CD)34 and vimentin on
Noppadol, Larbcharoensub, Jitchai, Kayankarnnavee, Suda, Sanpaphant, Kidakorn, Kiranantawat, Chewarat, Wirojtananugoon, Vorachai, Sirikulchayanonta   +5 more
openaire   +3 more sources

ESR1 methylation and ESR1 mutations in circulating tumor cells (CTCs) and paired plasma‐cfDNA of advanced breast cancer patients: A feasibility proof‐of‐concept study

Molecular Oncology, EarlyView.
Circulating tumor cells (CTCs) and plasma cell‐free DNA (cfDNA) were analyzed to detect ESR1 mutations and methylation in patients with advanced breast cancer. CTC‐derived DNA showed higher sensitivity for mutation detection and revealed complementary genetic and epigenetic alterations, highlighting the added value of CTC analysis for understanding ...
Dimitra Stergiopoulou, Athina Markou, Eleonora Nicolo, Mara S Serafini, Qiang Zhang, Youbin Zhang, Lorenzo Gerratana, Andrew A. Davis, Huiping Liu, William J Gradishar, Carolina Reduzzi, Massimo Cristofanilli, Evi Lianidou   +12 more
wiley   +1 more source