Results 151 to 160 of about 264,799 (308)

Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network

FEBS Letters, EarlyView.
Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley   +1 more source

Traction-assisted Endoscopic Retrograde Cholangiopancreatography Using an S-O Clip for Difficult Biliary Cannulation in Billroth II Reconstruction With Tumor-associated Distortion. [PDF]

DEN Open
Dainaka K, Ujihara R, Sawai T, Otsuka T, Yoshida J, Fujii H, Tomatsuri N, Sato H.   +7 more
europepmc   +1 more source

UW crew workout, 1948 (clip)

, 1948
Scenes of athletes training on shipboard. Groups of athletes pose for the camera. The UW crew's four man boat rowing on a channel.Title of clip supplied by cataloger.To order a reproduction, inquire about permissions, or for information about prices ...

core  

Partial depletion of plasminogen activator inhibitor‐1 decreases subcutaneous fat cell hypertrophy and liver cholesterol in high‐fat‐fed female mice

FEBS Letters, EarlyView.
Obesity raises blood levels of PAI‐1, a protein linked to metabolic dysfunction‐associated steatotic liver disease in people with obesity. In female mice fed a high‐fat diet, partially lowering PAI‐1 led to smaller subcutaneous fat cells and lower liver cholesterol, without changing body weight or insulin sensitivity.
Claudia E. Ramirez Bustamante, Robert Sharp, Pradip K. Saha, Elizabeth S. Anaya, Elizabeth L. Lieu, Evelyn L. de Groot, Pooja Patel, Mi Jeong Heo, Aaron R. Cox, Kang Ho Kim, Sean M. Hartig   +10 more
wiley   +1 more source

Dual-hook clip closure for high-tension gastric defects. [PDF]

Endoscopy
Hu X, Li C, Yang M, Huang X, Yang YC, Wang H.   +5 more
europepmc   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Metallic clip removal 40 years after scleral encircling surgery for retinal detachment: A case report. [PDF]

Am J Ophthalmol Case Rep
Matsumoto M, Matsubara H, Muramoto Y, Mase Y, Kato K, Kondo M.   +5 more
europepmc   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

A Universal Protein Ladder for Standardization of Diverse FRET Assays. [PDF]

Adv Sci (Weinh)
Smith ER, Gelder KL, Hunter-Craig L, Bose DA, Craggs TD, Twelvetrees AE.   +5 more
europepmc   +1 more source

CLIP-KD: An Empirical Study of CLIP Model Distillation [PDF]

Contrastive Language-Image Pre-training (CLIP) has become a promising language-supervised visual pre-training framework. This paper aims to distill small CLIP models supervised by a large teacher CLIP model.
Diao, Boyu, Bi, Junyu, An, Zhulin, Yang, Han, Xu, Yongjun, Yang, Chuanguang, Huang, Libo, Yu, Xinqiang   +7 more
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