Results 201 to 210 of about 427,365 (286)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Cross-modal deep generative models reveal the cortical representation of dancing. [PDF]

Nat Commun
Takagi Y, Shimizu D, Wakabayashi M, Ohata R, Imamizu H.   +4 more
europepmc   +1 more source

Multidetector computed tomographic characteristics of nonabsorbable polymer versus titanium ligature clips in a vascular model [PDF]

, 2008
Gary P. Foster, Michael Plunkett, Aaron Wagner, Selwin Abraham, D. Duane Baldwin, Bryan Hill, Hannah Kim   +6 more
openalex   +1 more source

PICALM::MLLT10 translocated leukemia

FEBS Letters, EarlyView.
This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen, Antonia C. Nakatsugawa, Natalie Barton, Henry Haines, Gary S. Stein, Janet L. Stein, Daniel S. Wechsler, Jessica L. Heath   +7 more
wiley   +1 more source

Complete closure of a large gastric defect after endoscopic submucosal dissection by double-layered suturing using wide-opening reopenable clips. [PDF]

Endoscopy
Takahashi Y, Shibagaki K, Kawamoto M, Suemitsu S, Kotani S, Ishimura N, Ishihara S.   +6 more
europepmc   +1 more source

Swallowing Fetus (ultrasound clip)

, 2023
Kehinde Lawal
openalex   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Successful Repair of a Strasberg E4 Bile Duct Injury With Double-Barreled Dual Hepaticojejunostomy: A Case Report. [PDF]

Cureus
Nassar M, Smith V, Tang D, Tang J.
europepmc   +1 more source

What does CLIP know about peeling a banana? [PDF]

Claudia Cuttano, Gabriele Rosi, Gabriele Trivigno, Giuseppe Averta   +3 more
openalex   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source