Results 91 to 100 of about 2,537 (222)

The Use of Dapagliflozin in the Treatment of Children With Severe Insulin Resistance

open access: yesPediatric Diabetes, Volume 2025, Issue 1, 2025.
Background Managing severe insulin resistance (IR) is challenging, necessitating a multifaceted approach, including dietary restriction, exercise, and pharmacotherapy. This paper will detail our utilization of dapagliflozin in a series of cases involving patients with severe IR of various etiology and inadequate glycemic control.
Najyya Attia   +7 more
wiley   +1 more source

Adrenocortical carcinoma: Report of two cases

open access: yesIndian Journal of Endocrinology and Metabolism, 2011
Adrenocortical carcinoma (ACC) is a rare neoplasm with a slight predilection for female patients. We report two cases of ACC. The first case was of a 7-year-old girl who presented with clitoromegaly.
C Aparna   +3 more
doaj   +1 more source

Congenital Adrenal Hyperplasia in Adults [PDF]

open access: yes, 2010
Congenital adrenal hyperplasia (CAH) is an autosomal recessive disorder affecting adrenal steroid synthesis. More than 95% of CAH cases are caused by reduced 21-hydroxylase function leading to variable extent of cortisol and aldosterone deficiency in ...
Falhammar, Henrik
core   +1 more source

Breast cancer in a transgender man

open access: yes
CA: A Cancer Journal for Clinicians, Volume 75, Issue 5, Page 376-386, September/October 2025.
Alison May Berner   +6 more
wiley   +1 more source

Phenotypes and clinical laboratory data for polycystic ovary syndrome cases: A nationwide survey in Japan

open access: yesJournal of Obstetrics and Gynaecology Research, Volume 50, Issue 12, Page 2346-2356, December 2024.
Abstract Aim Describe the current phenotypes and clinical laboratory data regarding polycystic ovary syndrome (PCOS) in Japan, taking into account ethnic differences and obesity status. Methods Data for 986 PCOS cases and 965 control cases were collected using a nationwide survey in Japan.
Hiroki Noguchi   +9 more
wiley   +1 more source

Long-term Complications of Female Genital Mutilation - Clitoral Epidermoid Inclusion Cyst

open access: yesBagcilar Medical Bulletin
This case study critically examines the long-term detrimental effects of female genital mutilation (FGM), specifically focusing on the development of clitoral epidermoid inclusion cysts.
Hilal Aktürk   +4 more
doaj   +1 more source

A case study in unethical transgressive bioethics: Letter of concern from bioethicists about the prenatal administration of dexamethasone. [PDF]

open access: yes, 2010
On February 3, 2010, a Letter of Concern from Bioethicists, organized by fetaldex.org, was sent to report suspected violations of the ethics of human subjects research in the off-label use of dexamethasone during pregnancy by Dr. Maria New.
Brent, Robert L   +3 more
core   +1 more source

A rare case of a 5‐year‐old girl with Klippel–Trénaunay syndrome and a bleeding focal vulvar hemangioma in Uganda

open access: yesClinical Case Reports, Volume 12, Issue 10, October 2024.
Key Clinical Message Klippel–Trénaunay syndrome can present with atypical manifestations such as a bleeding vulvar hemangioma. This case report, the first documented in Uganda, highlights the need for awareness of such presentations and underscores the importance of continuous follow‐up in female patients to manage potential complications throughout ...
Mundeli Simon Peter   +2 more
wiley   +1 more source

Prenatal and Pregnancy Management of Congenital Adrenal Hyperplasia

open access: yesClinical Endocrinology, Volume 101, Issue 4, Page 359-370, October 2024.
ABSTRACT Management of patients with congenital adrenal hyperplasia (CAH) poses challenges during pregnancy and prenatal stages, impacting fertility differently in men and women. Women with CAH experience menstrual irregularities due to androgen and glucocorticoid precursor interference with endometrial development and ovulation.
Hanna Franziska Nowotny   +3 more
wiley   +1 more source

A recurrent p.Arg92Trp variant in steroidogenic factor-1 (NR5A1) can act as a molecular switch in human sex development [PDF]

open access: yes, 2016
Cell lineages of the early human gonad commit to one of the two mutually antagonistic organogenetic fates, the testis or the ovary. Some individuals with a 46,XX karyotype develop testes or ovotestes (testicular or ovotesticular disorder of sex ...
Achermann, JC   +26 more
core   +2 more sources

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