Results 211 to 220 of about 252,165 (283)
Multi-proteomic analyses provide evidence for origin of a co-existing serum monoclonal gammopathy in CLL/MBL [PDF]
Uday Aditya Sarkar, Dylan Nicholas Tabang, Cliodna McNulty, Sabine Allam, Ayazhan Umutbayeva, Stacey M. Fernandes, Mariia Mikhaleva, Roberta S. Azevedo, Zainab Wurie, Ava Bidgoli, Natalie Onofri, J.E. Flinn, Kiyomi Mashima, Ingrid Lourme, Elisavet Vlachonikola, Binu K. Sasi, Paulina Predko, Andreas Agathangelidis, Kenneth C. Parker, Κώστας Σταματόπουλος, Irene M. Ghobrial, Jennifer R. Brown, Hanno Steen, Paolo Ghia +23 moreopenalex +1 more sourceBCR ligation induced by IgM stimulation results in gene expression and functional changes only in IgVH unmutated chronic lymphocytic leukemia (CLL) cells [PDF]
, 2008 Anna Guarini, Sabina Chiaretti, Simona Tavolaro, Roberta Maggio, Nadia Peragine, Franca Citarella, Maria Rosaria Ricciardi, Simona Santangelo, M Marinelli, Maria Stefania De Propris, Monica Messina, Francesca Romana Mauro, Ilaria Del Giudice, Robert Foà +13 moreopenalex +1 more sourceTargeting the Menin–KMT2A interaction in leukemia: Lessons learned and future directions
International Journal of Cancer, Volume 158, Issue 2, Page 342-356, 15 January 2026.Abstract
Chromosomal rearrangements involving the Mixed Lineage Leukemia gene (MLL1, KMT2A) are defining a genetically distinct subset in about 10% of human acute leukemias. Translocations involving the KMT2A‐locus at chromosome 11q23 are resulting in the formation of a chimeric oncogene, where the N‐terminal part of KMT2A is fused to a variety of ...Florian Perner, Jayant Y. Gadrey, Scott A. Armstrong, Michael W. M. Kühn +3 morewiley +1 more sourceCentral nervous system involvement in CLL: an international retrospective study by ERIC, the European Research Initiative on CLL. [PDF]
Blood AdvChatzikonstantinou T, Mikhaleva M, Brieghel C, Papangelou C, Minga E, Arrais-Rodrigues C, Besikli-Dimou S, Cerutti A, Doubek M, Enggaard L, Espinet B, Ferrer-Lores B, Garcia Vela JA, Gentile M, Vázquez EG, Gutwein O, Herishanu Y, Jablonowska-Babij P, Jaksic O, Josefsson P, Kalicińska E, Kislova M, Lista E, Kotsianidis I, Marquet J, Martino EA, McAuley C, Mela Osorio MJ, Moia R, Mosquera C, Nikitin E, Pavlovsky MA, Pfister V, Savaş EM, Scarfò L, Sever M, Shvidel L, Simkovic M, Stavroyianni N, Talimtzi P, Tranidou A, Visentin A, Vrachiolias G, Wasik-Szczepanek E, Wróbel T, Yağcı M, Cellini A, Chatzidimitriou A, Gaidano G, Anderson MA, Davids MS, Brown JR, Niemann CU, Stamatopoulos K, Ghia P, Ahn IE, Koren-Michowitz M. +56 moreeuropepmc +1 more sourceTreatability with ibrutinib plus venetoclax in patients with CLL in the real-world. the eric international thrive study [PDF]
Andrea Visentin, Thomas Chatzikonstantinou, Lydia Scarfò, Persefoni Talimtzi, Maria K. Angelopoulou, Tomáš Arpáš, Laura Ballotta, Leonidas Benetatos, Alessandro Bertolo, Horia Bumbea, Maurizio Cavallari, Anastasia Chatzidimitriou, Dominik Chraniuk, Anna Christoforidou, Francesca Cibien, Antonio Cuneo, Maria Ilaria Del Principe, Marina Deodato, Enrico Derenzini, Michael Doubek, Fabiana Esposito, Lucia Farina, Gianmarco Favrin, Isacco Ferrarini, Anna Maria Frustaci, Andrea Galitzia, Massimo Gentile, Iulia Virginia Iancu, Vanessa Innao, Krzysztof Jamroziak, Elżbieta Kalicińska, Maria Kislova, Ioannis Kyriakou, Luca Laurenti, Enrico Lista, Javier Loscertales, Alexandros Machairas, Giorgia Marcato, Francesca Martini, Nilla Maschio, Eva Minga, Riccardo Moia, Roberta Murru, Maura Nicolosi, Jacopo Olivieri, Carolina Pavlovsky, Miguel Arturo Pavlovsky, Sara Pepe, Ernesto Pérez Persona, Giuseppe Petruzzellis, Gian Matteo Rigolin, Alessandro Sanna, Marina P. Siakantaris, Paolo Sportoletti, Oana Stanca, Niki Stavrogianni, Tamar Tadmor, Annamaria Tomasso, Marzia Varettoni, Theodoros Vassilakopoulos, Eva Gimeno Vázquez, Candida Vitale, Mohamed A. Yassin, Mihnea Zdrenghea, Klaudia Zielonka, Livio Trentin, Κώστας Σταματόπουλος, Paolo Ghia +67 moreopenalex +1 more sourceEpigenetic reprogramming in multiple myeloma—Challenges and opportunities
International Journal of Cancer, Volume 158, Issue 2, Page 423-432, 15 January 2026.Abstract
In cancer, mutational processes act in concert with epigenetic reprogramming to endow malignant cells with hallmark properties that underpin tumorigenesis. Compared with the relatively rigid and slow processes of genetic evolution, the plastic nature of chromatin enables cells to adapt to a changing environment more rapidly.Subhasree Kumar, Lev M. Kats, Emily Gruber +2 morewiley +1 more sourceDNA methyltransferase inhibitors in hematological malignancies and solid tumors
International Journal of Cancer, Volume 158, Issue 2, Page 433-461, 15 January 2026.Abstract
Epigenetic modifications such as DNA methylation play a fundamental role in oncogenesis and the progression of neoplasms neoplasias. DNA methyltransferase inhibitors (DNMTi) constitute a family of therapeutic agents that impede the methylation at the 5‐position on cytosine nucleotides, thereby modulating the epigenetic regulation of tumor ...Valentin Wenger, Guillermo Garcia‐Manero, Robert Zeiser, Michael Lübbert +3 morewiley +1 more source