Results 91 to 100 of about 4,199 (162)

Longitudinal deep multi-omics profiling in a CLN3^Δex7/8 minipig model identifies biomarker signatures of disease. [PDF]

Commun Med (Lond)
Rechtzigel MJ, Lee B, Neville C, Huang T, Díaz R, Campos AR, Motamedchaboki K, Hornburg D, Johnson TB, Swier VJ, Weimer JM, Brudvig JJ.   +11 more
europepmc   +1 more source

Aneuploidy alleviates the cell proliferation defect caused by mutations affecting origin licensing in Saccharomyces cerevisiae. [PDF]

PLoS Genet
de La Roche Saint-André C.
europepmc   +1 more source

PPARα and RXRα in the regulation of neuronal ceroid lipofuscinosis genes: implications for Batten disease therapy. [PDF]

NeuroImmune Pharm Ther
Chandra S, Pahan K.
europepmc   +1 more source

Cross-Disorder Pruning-Plasticity-Aging Architecture in Substance Use Disorders and Anxiety: Transcriptome-Wide Association Insights and Mechanistic Synthesis. [PDF]

Cureus
Cheung N.
europepmc   +1 more source

Whi3key old fashioned: a condensate cocktail for cell fate decisions. [PDF]

Trends Cell Biol
Schmitz CO, Jain A.
europepmc   +1 more source

Protocol for screening of small molecules in a CLN3 disease patient-specific iPSC-derived neuronal progenitor cell model. [PDF]

STAR Protoc
Venkatesan R, Trippier PC.
europepmc   +1 more source

Therapeutic antisense oligonucleotide mitigates retinal dysfunction in a pig model of CLN3 Batten disease. [PDF]

Nucleic Acids Res
Stratton MP, Centa JL, Swier VJ, Pfeifer WL, Booth CD, Albert K, Hunyara JL, Rechtzigel MJ, Duelli FJ, Leppert HG, Rigo F, Smit T, Jafar-Nejad P, Weimer JM, Drack AV, Hastings ML.   +15 more
europepmc   +1 more source

Long-Term Open-Label Study Evaluating Oral Miglustat Treatment in Patients With Neuronal Ceroid Lipofuscinosis Type 3. [PDF]

Neurology
Pietrafusa N, Trivisano M, Calabrese C, De Dominicis A, Cappelletti S, Correale C, Salimbene L, Vallesi L, Corsetti T, Specchio N.   +9 more
europepmc   +1 more source

Visual Recovery and Neurological Stabilization Following Miglustat Treatment in Pediatric CLN3 Disease. [PDF]

J Child Neurol
Dutton AE, Whiteman IT, Jones MM, Geering KE, Afshar S, Johnson AM, Grigg JR.   +6 more
europepmc   +1 more source

CLN3 disease disrupts very early postnatal hippocampal maturation. [PDF]

Sci Rep
Singh JB, Burris DM, Bhuyan S, Thurston T, Oschmann A, Jankowski C, Lu W, Rabinowitz JD, Ahrens-Nicklas RC.   +8 more
europepmc   +1 more source