Results 91 to 100 of about 1,086,533 (280)

What to Do When Medical Evidence Can Only Be Generated Through Routine Data: An Example From Pediatric Oncology

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Children undergoing allogeneic stem cell transplantation often receive off‐label rituximab treatment for Epstein–Barr virus reactivation, using adult dosing without pediatric evidence. This project aims to develop a clinical decision support tool (CDSS) that provides evidence‐based dosing scenarios by analyzing real‐world patient data.
Birgit Burkhardt   +2 more
wiley   +1 more source

Epigenetic age-predictor for mice based on three CpG sites

open access: yeseLife, 2018
Epigenetic clocks for mice were generated based on deep-sequencing analysis of the methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by pyrosequencing at only three CG dinucleotides (CpGs) in the genes Prima1, Hsf4 ...
Yang Han   +9 more
doaj   +1 more source

The MedSupport Multilevel Intervention to Enhance Support for Pediatric Medication Adherence: Development and Feasibility Testing

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Introduction We developed MedSupport, a multilevel medication adherence intervention designed to address root barriers to medication adherence. This study sought to explore the feasibility and acceptability of the MedSupport intervention strategies to support a future full‐scale randomized controlled trial.
Elizabeth G. Bouchard   +8 more
wiley   +1 more source

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis   +13 more
wiley   +1 more source

Resveratrol Induces Myotube Development by Altering Circadian Metabolism via the SIRT1-AMPK-PP2A Axis

open access: yesCells
Resveratrol is a polyphenol known to have metabolic as well as circadian effects. However, there is little information regarding the metabolic and circadian effect of resveratrol on muscle cells.
Natalie Avital-Cohen   +2 more
doaj   +1 more source

Lifestyle Behaviors and Cardiotoxic Treatment Risks in Adult Childhood Cancer Survivors

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Higher doses of anthracyclines and heart‐relevant radiotherapy increase cardiovascular disease (CVD) risk. This study assessed CVD and CVD risk factors among adult childhood cancer survivors (CCSs) across cardiotoxic treatment risk groups and examined associations between lifestyle behaviors and treatment risks.
Ruijie Li   +6 more
wiley   +1 more source

DIAGNÓSTICO DA IMPLANTAÇÃO E IMPLEMENTAÇÃO DA NORMA REGULAMENTADORA 32 NOS ESTABELECIMENTOS DE SAÚDE: UM ESTUDO DE CASO EM UM HOSPITAL PÚBLICO DE JOINVILLE, SC - BRASIL

open access: yesAção Ergonômica, 2016
No Brasil não havia uma legislação federal específica que contemplasse os problemas encontrados nos ambientes laborais existentes no setor saúde. Com o intuito de promover a saúde dos trabalhadores na área da saúde foi aprovada a Norma Regulamentadora 32
Dayane Clock, Eduardo Concepción Batiz
doaj  

La matière des images dans The Duchess of Malfi

open access: yesSillages Critiques, 2019
The present paper explores the various types of painters and artists mentioned by John Webster in The Duchess of Malfi. Much like the poisoned portrait in The White Devil, some of the painted and sculpted images that appear in The Duchess of Malfi seem ...
Anne-Valérie Dulac
doaj   +1 more source

Non-destructive measurement of the transition probability in a Sr optical lattice clock

open access: yes, 2009
We present the experimental demonstration of non-destructive probing of the 1S0-3P0 clock transition probability in an optical lattice clock with 87Sr atoms. It is based on the phase shift induced by the atoms on a weak off-resonant laser beam.
F.-L. Hong   +5 more
core   +2 more sources

Cerebrospinal Fluid Liquid Biopsy Enables Targeted Therapy Without Tissue Diagnosis in Pediatric Low‐Grade Gliomas With BRAF V600E Mutation

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT We present two pediatric cases of pediatric low‐grade gliomas (PLGG) with BRAF V600E mutations diagnosed and monitored using cerebrospinal fluid (CSF) liquid biopsy analyzed via digital droplet PCR (ddPCR), without tissue biopsy. Both patients were treated with dabrafenib and trametinib and monitored through clinical assessments, magnetic ...
Hannah Sultan   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy