Results 101 to 110 of about 1,324,164 (376)
A stepwise emergence of evolution in the RNA world
FEBS Letters, EarlyView.How did biological evolution emerge from chemical reactions? This perspective proposes a gradual scenario of self‐organization among RNA molecules, where catalytic feedback on random mixtures plays the central role. Short oligomers cross‐ligate, and self‐assembly enables heritable variations. An event of template‐externalization marks the transition to
Philippe Nghe
wiley +1 more source
Nature, 1886 IN the absence of any details, apparently Mr. Wilson's simplest plan would be to insulate the hammer and bell of his “small striking clock,” and arrange that a galvanic current should pass through both, when they come in contact by the act of striking: this current of course to be directed to a large electro-magnet, to raise the hammer for striking on ...
openaire +7 more sources
FEBS Letters, EarlyView.B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro +2 more
wiley +1 more source
An immune clock of human pregnancy
Science immunology, 2017 High-dimensional analysis reveals the chronology of immunological adaptations during the course of human pregnancies. Following the hand of the immunological clock Immune function is altered during pregnancy to protect the fetus from an immunological ...
N. Aghaeepour +25 more
semanticscholar +1 more source
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Synchronization tracking in pulse position modulation receiver [PDF]
, 1987 A clock pulse generator for decoding pulse position modulation in an optical communication receiver is synchronized by a delay tracking loop which multiplies impulses of a data pulse by the square wave clock pulses from the generator to produce positive ...
Vilnrotter, Victor A.
core +1 more source
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
FUNCTIONAL IMPLICATIONS OF THE CLOCK 3111T/C SINGLE-NUCLEOTIDE POLYMORPHISM
Frontiers in Psychiatry, 2016 Circadian rhythm disruptions are prominently associated with Bipolar Disorder (BD). Circadian rhythms are regulated by the molecular clock, a family of proteins that function together in a transcriptional-translational feedback loop. The CLOCK protein is
Angela Renee Ozburn +8 more
doaj +1 more source
Multiphase clock-pulse generator uses simplified circuitry [PDF]
, 1965 Multiphase clock-pulse generator converts a simple pulse train into nonoverlapping clock pulses.
core +1 more source
Circulating histones as clinical biomarkers in critically ill conditions
FEBS Letters, EarlyView.Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez +17 more
wiley +1 more source