Results 121 to 130 of about 1,324,164 (376)
The choroid plexus is an important circadian clock component
Nature Communications, 2018 Mammalian circadian clocks have a hierarchical organization, governed by the suprachiasmatic nucleus (SCN) in the hypothalamus. The brain itself contains multiple loci that maintain autonomous circadian rhythmicity, but the contribution of the non-SCN ...
J. Myung +10 more
semanticscholar +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source
Ação Ergonômica, 2016 No Brasil não havia uma legislação federal específica que contemplasse os problemas encontrados nos ambientes laborais existentes no setor saúde. Com o intuito de promover a saúde dos trabalhadores na área da saúde foi aprovada a Norma Regulamentadora 32
Dayane Clock, Eduardo Concepción Batiz
doaj
Performance Analysis of Time Synchronization Protocols in Wireless Sensor Networks
Sensors, 2019 The time synchronization protocol is indispensable in various applications of wireless sensor networks, such as scheduling, monitoring, and tracking. Numerous protocols and algorithms have been proposed in recent decades, and many of them provide micro ...
Linh-An Phan +4 more
doaj +1 more source
Nature Methods, 2006 By allowing a differentiated somatic nucleus to form metaphase chromosomes its chromatin is remodeled in a way that adapts its replication properties to the early embryonic context.
openaire +3 more sources
Cyclic nucleotide signaling as a drug target in retinitis pigmentosa
FEBS Letters, EarlyView.Disruptions in cGMP and cAMP signaling can contribute to retinal dysfunction and photoreceptor loss in retinitis pigmentosa. This perspective examines the mechanisms and evaluates emerging evidence on targeting these pathways as a potential therapeutic strategy to slow or prevent retinal degeneration.
Katri Vainionpää +2 more
wiley +1 more source
Electronic system for drift clock calculation and synchronization for seafloor observatory [PDF]
, 2016 The paper describes a new electronic device that allows an easily measurement of the drift between a reference time source (usually GPS) and an atomic rubidium clock which is normally used in seafloor observatories.
Apponi, Umberto +3 more
core
Regulation of amyloid-β dynamics and pathology by the circadian clock
Journal of Experimental Medicine, 2018 Nighttime restlessness and daytime drowsiness are common and early symptoms of Alzheimer’s Disease (AD). This symptomology implicates dysfunctional biological timing, yet the role of the circadian system in AD pathogenesis is unknown.
G. Kress +6 more
semanticscholar +1 more source
TRAF2 binds to TIFA via a novel motif and contributes to its autophagic degradation
FEBS Letters, EarlyView.TRAF family members couple receptor signalling complexes to downstream outputs, but how they interact with these complexes is not always clear. Here, we show that during ADP‐heptose signalling, TRAF2 binding to TIFA requires two short sequence motifs in the C‐terminal tail of TIFA, which are distinct from the TRAF6 binding motif.
Tom Snelling +4 more
wiley +1 more source
Explores for the source of the gears in traditional Japanese clock (Wadokei)
Nihon Kikai Gakkai ronbunshu, 2017 The purpose of this study is to understand the nature of one of the oldest gears used in traditional Japanese clock. Today's gear manufacturing technology in Japan came mostly from Europe and America, but we do not know exactly, when and how the ...
Akio UEDA +4 more
doaj +1 more source