Results 41 to 50 of about 1,314,904 (274)

Cinnamic acid shortens the period of the circadian clock in mice

Biochemistry and Biophysics Reports, 2017
Cinnamic acid (CA) derivatives have recently received focus due to their anticancer, antioxidant, and antidiabetic properties. The present study aimed to determine the effects of cinnamic acid on the circadian clock, which is a cell-autonomous endogenous
Katsutaka Oishi, Saori Yamamoto, Hideaki Oike, Naoki Ohkura, Masahiko Taniguchi   +4 more
doaj   +1 more source

Clinical and genetic associations of the CLOCK circadian rhythm gene and depressive disorders in patients with alcohol dependence syndrome during the period of alcohol abstinence

Неврология, нейропсихиатрия, психосоматика, 2022
About 20% of patients with depression are diagnosed with alcohol dependence, and alcohol dependent individuals are at a higher risk of developing depression.
N. R. Tulbaeva, R. F. Nasyrova, D. A. Smirnova, Z. Sh. Ashurov, I. S. Efremov, V. S. Dobrodeeva, A. E. Abdrakhmanova, A. R. Asadullin   +7 more
doaj   +1 more source

Probabilistic Timed Automata with Clock-Dependent Probabilities [PDF]

, 2017
Probabilistic timed automata are classical timed automata extended with discrete probability distributions over edges. We introduce clock-dependent probabilistic timed automata, a variant of probabilistic timed automata in which transition probabilities ...
A Abate, G Bian, G Norman, JG Kemeny, M Jurdziński, M Kattenbelt, M Kwiatkowska, M Kwiatkowska, M Kwiatkowska, M Minsky, ML Puterman, N Basset, P Bouyer, R Alur   +13 more
core   +2 more sources

Coronary Anomalies: Left Main Coronary Artery Aneurysm

Case Reports in Cardiology, 2012
Coronary artery aneurysm is one of the rarest anomalies that we see in our medical practice and they are mostly associated with obstructive lesions due to atherosclerotic changes.
Rajsekhar Varda, Santosh Kumar Chitimilla, Aslam Lalani   +2 more
doaj   +1 more source

Effects of Kamikihito and Unkei-to on Sleep Behavior of Wild Type and Parkinson Model in Drosophila

Frontiers in Psychiatry, 2017
Parkinson’s disease (PD) is the second most common neurodegenerative disease, and it is associated with sleep behavior disorders. In Drosophila melanogaster disease model, human α-synuclein A30P overexpressing flies (A30P PD model) have been shown for ...
Kumpei Ito, Kumpei Ito, Kumpei Ito, Haruhisa Kawasaki, Haruhisa Kawasaki, Takahiro Suzuki, Takahiro Suzuki, Tsubasa Takahara, Tsubasa Takahara, Norio Ishida, Norio Ishida, Norio Ishida   +11 more
doaj   +1 more source

REVIEW OF RESEARCH ON THE RELATIONSHIP BETWEEN CIRCADIAN RHYTHMS AND CARCINOGENESIS USING ANIMAL MODELS

Сибирский онкологический журнал, 2021
Purpose of the study: to review in vivo studies on the relationship and role of various molecular genetic components of the circadian rhythm system in the initiation and development of malignant neoplasms.
G. S. Kireeva, E. A. Gubareva, M. A. Maydin, A. V. Panchenko, M. L. Tyndyk, E. I. Fedoros, S. S. Kruglov, V. K. Osetnik, V. N. Anisimov   +8 more
doaj   +1 more source

Frequency ratios of Sr, Yb and Hg based optical lattice clocks and their applications [PDF]

, 2015
This article describes the recent progress of optical lattice clocks with neutral strontium ($^{87}$Sr), ytterbium ($^{171}$Yb) and mercury ($^{199}$Hg) atoms.
Akatsuka, Tomoya, Das, Manoj, Katori, Hidetoshi, Nemitz, Nils, Ohkubo, Takuya, Ohmae, Noriaki, Takamoto, Masao, Takano, Tetsushi, Ushijima, Ichiro, Yamaguchi, Atsushi, Yamanaka, Kazuhiro   +10 more
core   +2 more sources

Cell-autonomous clock of astrocytes drives circadian behavior in mammals

Science, 2019
Astrocytes can drive the master clock in the brain The neurons of the suprachiasmatic nucleus (SCN) of the hypothalamus function as a central circadian clock, coordinating mammalian physiology with the 24-hour light-dark cycle. Brancaccio et al.
M. Brancaccio, Mathew D. Edwards, A. P. Patton, Nicola J. Smyllie, J. Chesham, E. Maywood, M. Hastings   +6 more
semanticscholar   +1 more source

Circadian Organization in Hemimetabolous Insects [PDF]

, 2004
The circadian system of hemimetabolous insects is reviewed in respect to the locus of the circadian clock and multioscillatory organization. Because of relatively easy access to the nervous system, the neuronal organization of the clock system in ...
Abe Y., Balkenohl M., Cymborowski B., Eskin A., Hardeland R., Helfrich-Förster C., Ikeda M., Mote M. I., Nishinokubi I., Petri B., Petri B., Pflugfelder O., Saifullah A. S. M., Shiga S., Tomioka K., Tomioka K., Tomioka K., Ushirogawa H.   +17 more
core   +1 more source

Recalibrating the epigenetic clock: implications for assessing biological age in the human cortex

bioRxiv, 2020
Human DNA-methylation data have been used to develop biomarkers of ageing - referred to ‘epigenetic clocks’ - that have been widely used to identify differences between chronological age and biological age in health and disease including ...
Gemma L Shireby, Jonathan P. Davies, P. Francis, Joe Burrage, Emma M Walker, Grant W. A. Neilson, Aisha Dahir, Alan J. Thomas, S. Love, Rebecca G. Smith, K. Lunnon, M. Kumari, L. Schalkwyk, K. Morgan, K. Brookes, E. Hannon, J. Mill   +16 more
semanticscholar   +1 more source