Results 51 to 60 of about 1,314,904 (274)
We recently found that the mRNA expression of Slc25a25, a Ca2+-sensitive ATP carrier in the inner mitochondrial membrane, fluctuates in a circadian manner in mouse skeletal muscle.
Reiko Nakao+2 more
doaj +1 more source
FUNCTIONAL IMPLICATIONS OF THE CLOCK 3111T/C SINGLE-NUCLEOTIDE POLYMORPHISM
Circadian rhythm disruptions are prominently associated with Bipolar Disorder (BD). Circadian rhythms are regulated by the molecular clock, a family of proteins that function together in a transcriptional-translational feedback loop. The CLOCK protein is
Angela Renee Ozburn+8 more
doaj +1 more source
Progression of clock DBD changes over time [PDF]
Day-boundary discontinuity (DBD) is an effect present in precise GNSS satellite orbit and clock products originating from the method used for orbit and clock determination.
Kamil Maciuk, Inese Varna, Jacek Kudrys
doaj +1 more source
A quantum clock must satisfy two basic constraints. The first is a bound on the time resolution of the clock given by the difference between its maximum and minimum energy eigenvalues.
A. Peres+16 more
core +2 more sources
The three large images that adorn folios 4v, 19v and 25v of the 12th-century cartulary have already been extensively studied and commented upon and continue to raise numerous problems of interpretation.
Jacques Le Maho
doaj +1 more source
Atomic Properties of Lu$^+$ [PDF]
Singly ionised Lutetium has recently been suggested as a potential clock candidate. Here we report a joint experimental and theoretical investigation of \ce{Lu^+}.
Arnold, K. J.+7 more
core +3 more sources
Abstract The immune system has been for long considered a marker of health. The age-related decline in its function results in a greater incidence of infections, autoimmune diseases, and cancer. Nevertheless, it is still not known if immune function can be used to accurately estimate the rate of aging of an individual. A set of 14 immune
Carmen Vida+3 more
openaire +2 more sources
Epigenetic age-predictor for mice based on three CpG sites
Epigenetic clocks for mice were generated based on deep-sequencing analysis of the methylome. Here, we demonstrate that site-specific analysis of DNA methylation levels by pyrosequencing at only three CG dinucleotides (CpGs) in the genes Prima1, Hsf4 ...
Yang Han+9 more
doaj +1 more source
The Clock Takes Shape—24 h Dynamics in Genome Topology
Circadian rhythms orchestrate organismal physiology and behavior in order to anticipate daily changes in the environment. Virtually all cells have an internal rhythm that is synchronized every day by Zeitgebers (environmental cues). The synchrony between
Kévin Tartour, Kiran Padmanabhan
doaj +1 more source
A whole lifespan mouse multi-tissue DNA methylation clock
Age predictors based on DNA methylation levels at a small set of CpG sites, DNAm clocks, have been developed for humans and extended to several other species.
Margarita V Meer+3 more
doaj +1 more source