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Toxicologic studies on clomiphene
Toxicology and Applied Pharmacology, 1966The results of acute and chronic toxicity studies with clomiphene citrate in rats and dogs are presented. The acute lethal doses (LD-50s) for clomiphene citrate in rats were 530 and 5750 mg/kg for the intraperitoneal and oral routes respectively. In rats given clomiphene citrate at dosages of 5 15 and 40 mg/kg/day for 53 weeks food consumption and ...
J W, Newberne, W L, Kuhn, J R, Elsea
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Clomiphene and dexamethasone in women unresponsive to clomiphene alone.
Obstetrics and gynecology, 1982Twelve oligomenorrhic women with polycystic ovary syndrome (PCO) in whom clomiphene (250 mg daily for 5 days) and 10,000 IU human chorionic gonadotropin had failed to induce ovulation were treated with clomiphene and dexamethasone. Eight of the 12 women underwent complete hormonal assessment during treatment.
R A, Lobo +4 more
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Clomiphene-lnduced Mood Swings
Journal of Obstetric, Gynecologic & Neonatal Nursing, 1991A study of couples' perceptions of infertility treatment with clomiphene (clomiphene citrate) revealed mood swings in 9 out of 14 women using the drug. This paper describes the mood swings and the responses of women and their spouses. Three phases of mood swing response emerged from the data: lacking awareness of the relation of the mood swings to the ...
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Drug and Therapeutics Bulletin, 1967
Clomiphene citrate (Clomid - Merrell) has recently been introduced to treat failure of ovulation. It is chemically related to chlorotrianisene (Tace - Merrell), a non-steroid synthetic oestrogen, and also to triparanol (MER 29 - Merrell), an inhibitor of cholesterol synthesis. The introductory advertising has been admirably restrained and informative.
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Clomiphene citrate (Clomid - Merrell) has recently been introduced to treat failure of ovulation. It is chemically related to chlorotrianisene (Tace - Merrell), a non-steroid synthetic oestrogen, and also to triparanol (MER 29 - Merrell), an inhibitor of cholesterol synthesis. The introductory advertising has been admirably restrained and informative.
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Menometrorrhagia of the puberty: therapy with Clomiphene (Clomiphene and puberal menometrorrhagia).
Acta Europaea fertilitatis, 1977The authors administrated the Clomiphene, in different doses, to 8 patients among 27 observed. These patients were checked for a long time by basal body temperature and in some cases, measuring total urinary estrogens and pregnandioluria. The therapy was administrated in 38 cicles of the 163 cicles observed.
Garcea, Nicola +4 more
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Contraception, fertilite, sexualite (1992), 1993
Thanks to CC an important number of endocrine sterility has been cured. The antiestrogenic effect of CC has been accused to promote perturbations of cervical mucus secretion and endometrial receptivity. The different technics to assure correction of negative side effects while promoting optimal activity of clomiphene will be discussed in terms of ...
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Thanks to CC an important number of endocrine sterility has been cured. The antiestrogenic effect of CC has been accused to promote perturbations of cervical mucus secretion and endometrial receptivity. The different technics to assure correction of negative side effects while promoting optimal activity of clomiphene will be discussed in terms of ...
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