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Clomiphene, a selective estrogen receptor modulator (SERM), has been used for the treatment of anovulation for more than 50 years. However, since (E)-clomiphene ((E)-Clom) and its metabolites are eliminated primarily via Cytochrome P450 (CYP) 2D6 and ...
Christina Kovar+11 more
doaj +1 more source
THE ACTION OF CLOMIPHENE IN THE EWE [PDF]
Summary. Three tests are described, two each with thirty-six entire and one with fifty-six spayed ewes, in which the action of clomiphene citrate was characterized in the sheep. It was found to suppress pituitary activity, to induce behavioural oestrus and to have a grossly stimulatory action on the uterus in that it induced a high incidence of hydrops
T. J. Robinson, D. R. Lindsay
openaire +3 more sources
Clomiphene, a selective oestrogen receptor modulator, has been utilised in managing male sub‐fertility since 1967. Numerous controlled and uncontrolled studies have been published regarding the efficacy of clomiphene citrate in male sub‐fertility cohorts.
T. Gundewar, M. Kuchakulla, R. Ramasamy
semanticscholar +1 more source
Clomiphene Citrate Treatment Cycle Outcomes of Polycystic Ovary Syndrome Patients Based on Basal High Sensitive C-Reactive Protein Levels: A Cross-Sectional Study [PDF]
Background Polycystic ovary syndrome (PCOS) is highly associated with an ovulatory infertility, features of the metabolic syndrome, including obesity, insulin resistance and dyslipidemia. Serum concentrations of high sensitive C-reactive protein (hs-CRP)
Serkan Kahyaoglu+7 more
doaj +1 more source
Correlation between obesity and successful ovulation induction with Clomiphene citrate
Ovulation induction with clomiphene citrate is a hormonal therapy for infertile women with impaired ovarian function caused by dysregulation of the hypothalamus and pituitary, affecting egg development and ovulation.
Rida Eka Setiani+2 more
doaj +1 more source
Comparison of Treatment Outcomes of Infertile Women by Clomiphene Citrate and Letrozole with Gonadotropins Underwent Intrauterine Insemination [PDF]
This study was designed to compare the effect of clomiphene and letrozole in ovulatory stimulation in infertile women under intrauterine insemination who referred to Mahdiyeh infertility clinic during 2008-2009.
Shahrzad Zadehmodares+4 more
doaj +1 more source
Objective: To compare the different polycystic ovarian syndrome (PCOS) phenotypes based on their clinical, metabolic, hormonal profile, and their differential response to clomiphene. Design: Prospective observational study. Setting: Infertility clinic, a
Garima Sachdeva+4 more
semanticscholar +1 more source
Function and Sexual Satisfaction of Women Treated with Two Types of Ovulation Stimulant Drugs: Clomiphene and Letrozole [PDF]
Introduction: Infertility is one of the factors which have a significant effect on the sexual performance of couples, especially women. Infertility can affect sexual activity in infertile couples.
Razieh Shams Mourkani+2 more
doaj +1 more source
Clomiphene Citrate for Male Hypogonadism and Infertility: An Updated Review
Clomiphene citrate (CC) is a selective estrogen receptor modulator, originally developed in 1956 and introduced into clinical medicine in 1967 for the treatment of female infertility.
B. Herzog+3 more
semanticscholar +1 more source
Tamoxifen: An alternative to clomiphene in women with polycystic ovary syndrome
Background : Clomiphene citrate is commonly used for ovulation induction in women with anovulatory infertility. However, pregnancy rates with this drug are not as good as ovulation rates.
Lakhbir Kaur Dhaliwal+3 more
doaj +1 more source