Results 41 to 50 of about 6,750 (158)

Compared Antileishmanial Activity of Clomiphene and Tamoxifen

Biomedicines
Drug repositioning is an efficient strategy to search for new treatment alternatives that is especially valuable for neglected parasitic diseases such as leishmaniasis. Tamoxifen and raloxifene are selective estrogen receptor modulators (SERMs) that have
Sergio Sifontes-Rodríguez, Alma Reyna Escalona-Montaño, Ricardo Mondragón Flores, Niurka Mollineda-Diogo, Lianet Monzote Fidalgo, Mónica Edith Mondragón-Castelán, Fedra Alardin-Gutiérrez, Lourdes Araceli López-Enzana, Daniel Andrés Sánchez-Almaraz, Ofelia Pérez-Olvera, María Magdalena Aguirre-García   +10 more
doaj   +1 more source

Is combined letrozole and clomiphene superior to either as monotherapy: a systemic review and meta-analysis based on clinical trials

Gynecological Endocrinology
Objective This research was conducted to assess the therapeutic advantage of combined letrozole and clomiphene citrate versus monotherapy for polycystic ovarian syndrome (PCOS) patients.Study Design Five databases were searched using the search string ...
Anusha Ashkar, Bismeen Jadoon, Mirza Mehmood Ali Baig, Shayan A. Irfan, Mona El-Gayar, Fatima Zulfiqar Siddiqui   +5 more
doaj   +1 more source

Lemongrass (Cymbopogon citratus) Extracts Ameliorate Polycystic Ovary Syndrome in Rats by Inhibiting Follicular Atresia and Modulating Ghrelin and Leptin

Biochemistry Research International, Volume 2026, Issue 1, 2026.
Polycystic ovary syndrome (PCOS) accelerates ovarian follicular depletion through atresia. This study investigated the therapeutic potential of aqueous (AE) and hydroethanolic (HEE) extracts of Cymbopogon citratus in mitigating PCOS‐induced ovarian damage (specifically ferroptosis, apoptosis, and oxidative stress) in a rat model of PCOS.
Vanis Slauvers Akago, Marie Alfrede Mvondo, Sefirin Djiogue, Stephen Lacmata Tamekou, Nina-Sonia Messongue Mbollo, Josue Jobin Biba, Agatha Yelah Ntumnyuy, Lylie Gisèle Atsafack Mboudem, Perpetue Atsama Mbede, Christophe Mezui, Hélène Carole Edima-Durand, Jules-Roger Kuiate, Dieudonné Njamen, Yoel Klug   +13 more
wiley   +1 more source

The first Australian evidence‐based guidelines on male infertility

Medical Journal of Australia, Volume 223, Issue 11, Page 653-663, December 2025.
Abstract Introduction Infertility affects about one in six couples and a male factor may contribute to 50% of cases. Until recently, no Australian‐based clinical guidelines for the management of male infertility had been published. A panel of experts was assembled to formulate the first Australian evidence‐based guidelines on male infertility.
Darren J Katz, Liza O’Donnell, Robert I McLachlan, Tim J Moss, Clare V Boothroyd, Veena Jayadev, Sarah R Catford   +6 more
wiley   +1 more source

Efficacy of Acupuncture in Alleviating Negative Emotions in Polycystic Ovary Syndrome: A Systematic Review and Meta‐Analysis

Brain and Behavior, Volume 15, Issue 12, December 2025.
This meta‐analysis of seven RCTs (n = 489) demonstrates that acupuncture significantly improves depression scores, hirsutism, and BMI in PCOS patients, though anxiety symptoms show no significant improvement. Evidence quality is low, warranting cautious interpretation. ABSTRACT Introduction Preliminary studies have indicated that acupuncture may play a
Lanfeng Lai, Zhennan Wu, Jiayi Zhao, Jiahuan Li, Boxiong Wu, Han Yang, Nenggui Xu, Wei Yi   +7 more
wiley   +1 more source

A Review of First Line Infertility Treatments and Supporting Evidence in Women with Polycystic Ovary Syndrome

Medical Sciences, 2019
Polycystic ovary syndrome (PCOS) is the most common cause of anovulatory infertility in women of reproductive age. Lifestyle change is considered the first line treatment for the management of infertile anovulatory women with PCOS, and weight loss for ...
Michael Costello, Rhonda Garad, Roger Hart, Hayden Homer, Louise Johnson, Cailin Jordan, Edgar Mocanu, Jie Qiao, Luk Rombauts, Helena J. Teede, Eszter Vanky, Christos Venetis, William Ledger   +12 more
doaj   +1 more source

The Effect of Hypnotherapy on the Resilience of Women With Polycystic Ovarian Syndrome: Study Protocol for a Randomized Controlled Trial

Health Science Reports, Volume 8, Issue 12, December 2025.
ABSTRACT Background and Aims Polycystic ovarian syndrome, with a mean incidence of 5–10, is the most common endocrine disorder affecting women of reproductive age. These patients suffer from a wide range of symptoms that are inversely related to their resilience and quality of life.
Soghra Khani, Zohreh Shahhosseini, Mahdi pourasghar, Roya Nikbakht, Mahtab Hajimohammadreza   +4 more
wiley   +1 more source

EVALUATION OF LETROZOLE THERAPEUTIC EFFECT IN INFERTILE WOMEN [PDF]

Acta Medica Iranica, 2007
Combination therapy with clomiphene citrate plus gonadotropin (clomiphene citrate plus HMG) in induction ovulation reduce the gonadotropins dose but antiestrogenic effect of c.c. can decrease pregnancy rate.
F. Akbary-Asbagh, Z. Heidar, F. Frozan-Fard, K. Nouri, O. Azmodeh, A. Ghasemynejad, N. Salsabily M. Amirian   +6 more
doaj   +1 more source

Pharmacotherapy of infertility in Ghana: retrospective study at the cape coast teaching hospital

Journal of Pharmaceutical Policy and Practice, 2019
Background Infertility is a major challenge for couples globally. Due to low income levels and the high cost of other assisted reproductive techniques, pharmacotherapy remain the major first line treatment option for infertility in Sub-Saharan Africa ...
Stephen Mensah Arhin, Kwesi Boadu Mensah, Evans Agbeno, Vitus Sambo Badii, Charles Ansah   +4 more
doaj   +1 more source

Clomiphene based ovarian stimulation in a commercial donor program

Journal of Human Reproductive Sciences, 2015
OBJECTIVE: This study was conducted to compare an extended clomiphene-based ovarian stimulation regimen with the conventional antagonist protocol in donor-recipient cycles.
Shruti Gupta, Ruma Satwik, Abha Majumdar, Shweta Mittal, Neeti Tiwari   +4 more
doaj   +1 more source