Results 41 to 50 of about 10,884 (201)

The Known and Unknown About Female Reproductive Tract Mucus Rheological Properties

BioEssays, Volume 47, Issue 6, June 2025.
Mucus viscosity changes as spermatozoa travel through the female reproductive tract to the egg in humans, bovines, mice, and other mammals. These changes may aid in spermatozoa navigation. However, limited information is available on the viscoelastic properties of female reproductive tract mucus, and consistent measurement techniques are lacking ...
Luke Achinger, Derek F. Kluczynski, Abigail Gladwell, Holly Heck, Faith Zhang, Ethan Good, Alexis Waggoner, Mykala Reinhart, Megan Good, Dawson Moore, Dennis Filatoff, Supriya Dhar, Elisa Nigro, Lucas Flanagan, Sunny Yadav, Trinity Williams, Aniruddha Ray, Tariq A. Shah, Matthew W. Liberatore, Tomer Avidor‐Reiss   +19 more
wiley   +1 more source

The clinical value of progestin-primed ovarian stimulation protocol for women with diminished ovarian reserve undergoing IVF/ICSI: a systematic review and meta-analysis

Frontiers in Endocrinology, 2023
BackgroundTo determine whether progestin-primed ovarian stimulation (PPOS) is more effective for women with diminished ovarian reserve (DOR) than clomiphene citrate (CC)/letrozole (LE) plus gonadotropin in IVF or ICSI treatment.MethodsNine databases were
Guangyao Lin, Xiufang Zhong, Shengnan Li, Xiyu Liu, Lianwei Xu   +4 more
doaj   +1 more source

A Comprehensive CYP2D6 Drug–Drug–Gene Interaction Network for Application in Precision Dosing and Drug Development

Clinical Pharmacology &Therapeutics, Volume 117, Issue 6, Page 1718-1731, June 2025.
Conducting clinical studies on drug–drug‐gene interactions (DDGIs) and extrapolating the findings into clinical dose recommendations is challenging due to the high complexity of these interactions. Here, physiologically‐based pharmacokinetic (PBPK) modeling networks present a new avenue for exploring such complex scenarios, potentially informing ...
Simeon Rüdesheim, Helena Leonie Hanae Loer, Denise Feick, Fatima Zahra Marok, Laura Maria Fuhr, Dominik Selzer, Donato Teutonico, Annika R. P. Schneider, Juri Solodenko, Sebastian Frechen, Maaike van der Lee, Dirk Jan A. R. Moes, Jesse J. Swen, Matthias Schwab, Thorsten Lehr   +14 more
wiley   +1 more source

Spina bifida as a multifactorial birth defect: Risk factors and genetic underpinnings

Pediatric Discovery, Volume 3, Issue 2, June 2025.
Abstract Spina bifida is a birth defect resulting from abnormal embryonic development of the neural tube. Though spina bifida is divided into several subtypes, myelomeningocele—the most severe form of spina bifida often associated with a markedly diminished quality of life—accounts for a significant portion of cases.
Ethan S. Wong, Daniel A. Hu, Lily Zhang, Rachel Qi, Cindy Xu, Ou Mei, Guowei Shen, Wulin You, Changqi Luo, Tong‐Chuan He, Russell R. Reid, Lewis S. Shi, Michael J. Lee, Yi Zhu   +13 more
wiley   +1 more source

Effect of oral Tadalafil on endometrial thickness in patients receiving Clomiphene citrate for ovulation induction

Middle East Fertility Society Journal, 2018
Background: Adequate and optimum endometrial development is required for a successful pregnancy to occur. Clomiphene citrate is well known for its negative impact on endometrial thickness.
Islam Mohamed Magdi Ammar, Mostafa Abdo Ahmed Salem   +1 more
doaj  

Systematic Review and Meta‐Analysis on the Prevalence of Radiotherapy‐Induced Hypopituitarism in Adults With Primary Non‐Pituitary Brain Tumours

Clinical Endocrinology, Volume 102, Issue 6, Page 683-698, June 2025.
ABSTRACT Context It is well recognised there is a high prevalence of pituitary dysfunction in childhood brain tumours survivors who are treated with radiotherapy. In contrast, the potential for survivors of brain tumours arising in adulthood to develop radiotherapy‐induced hypopituitarism may be underestimated.
Darran Mc Donald, Maria Tomkins, Liam O'Connell, David Fitzpatrick, Clare Faul, Michael W. O'Reilly, Kathleen Bennett, Mark Sherlock   +7 more
wiley   +1 more source

12- THE NUMBER OF FOLLICLES AND OVARIAN VOLUME IN THE ASSESSMENT OF RESPONSE TO CLOMIPHENE CITRATE TREATMENT IN WOMEN WITH POLYCYSTIC OVARIAN SYNDROME [PDF]

Basrah Journal of Surgery, 2011
Haifa Al-Shaheen CABOG, Consultant Obstetrician & Gynecologist, Basrah Maternity & Childhood Hospital E-mail: hayfa_alshaheen@yahoo.com Abstract This prospected follow–up study was carried out over 12 months period (from 1st September 2008 till 30th ...
Haifa Al-Shaheen
doaj   +1 more source

Metformin use in women with polycystic ovary syndrome (PCOS): Opportunities, benefits, and clinical challenges

Diabetes, Obesity and Metabolism, Volume 27, Issue S3, Page 31-47, June 2025.
Abstract Metformin, a synthetic biguanide, is widely used to manage type 2 diabetes, and is commonly prescribed in polycystic ovary syndrome (PCOS) to address insulin resistance and associated metabolic and reproductive disturbances. PCOS is characterised by hormonal imbalances such as hyperandrogenism and anovulation, metabolic abnormalities including
Saeede Saadati, Taitum Mason, Rasoul Godini, Eszter Vanky, Helena Teede, Aya Mousa   +5 more
wiley   +1 more source

Multicenter cohort study of the effect of Crinone® progesterone vaginal gel alone to prepare the endometrium for frozen–thawed blastocyst transfer in a hormone replacement cycle

Journal of Obstetrics and Gynaecology Research, Volume 51, Issue 6, June 2025.
Abstract Aim Progesterone has to be administered to prepare the endometrium for frozen–thawed blastocyst transfer (FBT) in a hormone replacement cycle (HRC). The objective of this study was to investigate the efficacy and safety of using Crinone® progesterone gel alone in HRC‐FBT.
Akiko Takashima, Yukihiro Shibui, Toshio Hamatani, Akihiko Suenaga, Yoshimitsu Kuwabara, Fuminori Kimura, Koji Nakagawa, Yusuke Fukuda, Shoji Tokunaga, Yukiko Katagiri   +9 more
wiley   +1 more source

Cabergoline Use and Pregnancy Outcomes: A Systematic Review

Birth Defects Research, Volume 117, Issue 3, March 2025.
ABSTRACT Introduction Lack of available expert guidelines leads clinicians to interrupt cabergoline treatment upon confirmation of pregnancy and consider switching to bromocriptine, which is more commonly used during pregnancy but is poorly tolerated.
Anne‐Sophie Otis, Marie‐Sophie Brochet, Zoë Tremblay, Jacques Balayla, Elias M. Dahdouh   +4 more
wiley   +1 more source