Results 191 to 200 of about 4,087 (281)

TONSL Promotes Hepatocellular Carcinoma Progression by Inhibiting Apoptosis Through Homologous Recombination Repair

Cancer Science, EarlyView.
In hepatocellular carcinoma, the 8q24.3 locus is frequently amplified and is associated with tumor‐specific overexpression of TONSL. TONSL promotes homologous recombination repair through RAD51, limits γH2AX accumulation and apoptosis, supports tumor growth, and its loss increases sensitivity to poly (ADP‐ribose) polymerase (PARP) inhibition.
Akinori Tsujimoto, Hajime Otsu, Takashi Ofuchi, Tomohiko Ikehara, Kosuke Hirose, Shohei Shibuta, Kazuki Omachi, Yu Takahashi, Yuya Ono, Satoshi Higuchi, Takanari Tatsumi, Kiyotaka Hosoda, Qingjiang Hu, Yusuke Yonemura, Takaaki Masuda, Masayuki Sho, Koshi Mimori   +16 more
wiley   +1 more source

Needle- and Canopy-Level Genetic Variation in Scots Pine (<i>Pinus sylvestris</i> L.) Revealed by Hyperspectral Phenotyping Across Sites and Seasons. [PDF]

Evol Appl
Provazník D, Stejskal J, Lhotáková Z, Čepl J, Neuwirthová E, Nofrizal AY, Korecký J, Červená L, Kupková L, Klápště J, Hansen JK, Gezan SA, Campbell P, Lstibůrek M, Albrechtová J.   +14 more
europepmc   +1 more source

Multi‐Spectral Gaussian Splatting with Neural Color Representation

Computer Graphics Forum, EarlyView.
Abstract 3D Gaussian Splatting (3DGS) [KKLD23] has transformed novel‐view synthesis from RGB images, yet remains restricted to the visible spectrum. Many applications, including agricultural monitoring, rely on multi‐spectral imaging, where spectral camera alignment and scalability pose major challenges.
Lukas Meyer, Josef Grün, Maximilian Weiherer, Bernhard Egger, Marc Stamminger, Linus Franke   +5 more
wiley   +1 more source

Age‐specific melanoma risk associated with nevi: a pooled analysis from the M‐SKIP project

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Summary Objective This study investigates the association of melanoma risk with total‐body nevus count and the presence of atypical nevi in younger (< 40 years) and older (> 60 years) individuals. Methods A pooled analysis was conducted within the M‐SKIP project, based on multiple melanoma case‐control studies.
Giulia Doi, Aurora Gaeta, Simone Ribero, Nelleke Gruis, Julia Newton‐Bishop, David Polsky, DeAnn Lazovich, Paola Ghiorzo, Gloria Ribas, Chiara Menin, Alexander J. Stratigos, Gabriella Guida, Susana Puig, Maria Concetta Fargnoli, Peter A. Kanetsky, Paola Queirolo, Vincenzo Bagnardi, Veronique Bataille, Sara Raimondi, Sara Gandini, M‐SKIP study group   +20 more
wiley   +1 more source

Telomere to Telomere Genome Assembly and Efficient Transformation and Genome Editing in Populus euphratica. [PDF]

Plant Biotechnol J
An Y, Yang R, Yang S, Gou X, Li Y, Dong Y, Zhou Y, Han X.   +7 more
europepmc   +1 more source

Semiological features of epilepsy seizures and paroxysmal non‐epileptic events in children: A systematic review and meta‐analysis

Developmental Medicine &Child Neurology, EarlyView.
Pediatric paroxysmal non‐epileptic events (PNEs) are frequently misdiagnosed as epilepsy. We systematically reviewed and synthesized 40 studies, including 3123 video‐EEG monitored pediatric patients. Epileptic seizures in infants (1 month–3 years) typically presented as arrest, while in children and adolescents (1 month–21 years) they manifested as ...
Tímea Lőrincz‐Molnár, Márk Viktor Hernádfői, Krisztina Szalkay, Réka Tóth, Marie Anne Engh, Péter Kiss, Miklós Garami, Péter Hegyi, András Fogarasi   +8 more
wiley   +1 more source

Haplotype-resolved genome of 'Pinot Noir' reveals DNA polymorphisms and allele-specific expression shaping terroir adaptation. [PDF]

Mol Hortic
Shangguan L, Ren Y, Xuan X, Li S, Pei D, Chen X, Zhang R, Mou D, Wang X, Chen W, Xu M, Leng X, Guan L, Chen J, Wang S, Fan H, Salman HM, Fang J.   +17 more
europepmc   +1 more source

Colonization and extinction lags drive non‐linear responses to warming in mountain plant communities across the Northern Hemisphere

Ecography, EarlyView.
Global warming is changing plant communities due to the arrival of new species from warmer regions and declining abundance of cold‐adapted species. However, experimentally testing predictions about trajectories and rates of community change is challenging because we normally lack an expectation for future community composition, and most warming ...
Billur Bektaş, Chelsea Chisholm, Dagmar Egelkraut, Joshua Lynn, Sebastián Block, Thomas Deola, Fanny Dommanget, Brian J. Enquist, Deborah E. Goldberg, Sylvia Haider, Aud H. Halbritter, Yongtao He, Renaud Jaunatre, Anke Jentsch, Kari Klanderud, Paul Kardol, Susanne Lachmuth, Gregory Loucougaray, Tamara Münkemüller, Georg Niedrist, Hanna Nomoto, Lorah Seltzer, Joachim Paul Töpper, Lisa J. Rew, Tim Seipel, Manzoor A. Shah, Richard James Telford, Tom W.N. Walker, Shiping Wang, David A. Wardle, Peter Wolff, Yan Yang, Vigdis Vandvik, Jake M. Alexander   +33 more
wiley   +1 more source

Clonal parental effects on competitive interactions between two duckweeds. [PDF]

Front Plant Sci
He LX, Jin Y, Zhang XM, Luo FL, Xue W, Lei JP, Liu H, Yu FH.   +7 more
europepmc   +1 more source

First‐Line Treatment of IGHV‐Unmutated Chronic Lymphocytic Leukemia: A Network Meta‐Analysis of Targeted and Chemoimmunotherapy Regimens

European Journal of Haematology, EarlyView.
ABSTRACT Immunoglobulin heavy chain variable region‐unmutated (IGHV‐U) chronic lymphocytic leukemia (CLL) represents a biologically aggressive subgroup with limited responsiveness to chemoimmunotherapy (CIT). To clarify the comparative effectiveness of available frontline options, we conducted a comprehensive Bayesian network meta‐analysis of ...
Santino Caserta, Enrica Antonia Martino, Danilo Lofaro, Ernesto Vigna, Antonella Bruzzese, Francesco Mendicino, Maria Eugenia Alvaro, Caterina Labanca, Eugenio Lucia, Virginia Olivito, Nicola Amodio, Fortunato Morabito, Valter Gattei, Massimo Gentile   +13 more
wiley   +1 more source