Results 41 to 50 of about 4,087 (281)

Derivation and characterization of retinal pigment epithelium from urine‐derived iPSCs

FEBS Open Bio, EarlyView.
Age‐related macular degeneration causes vision loss via RPE dysfunction and loss. Traditional iPSC therapies rely on invasive biopsies, limiting scalability. Here, we utilize urine‐derived stem cells as an accessible source to generate u‐iPSCs, successfully differentiated into pigmented RPE. This “Urine‐to‐Retina” platform provides a promising path for
Daniella Beiner, Hainan Zhu, Carol Christine Bosholm, Heuy‐Ching Wang, Tracy Criswell, Anthony Atala, Jian‐Xing Ma, Yuanyuan Zhang   +7 more
wiley   +1 more source

Prognostic significance of tumor microenvironment assessed by machine learning algorithm in surgically resected non‐small cell lung cancer

Cancer Reports, EarlyView., 2023
Abstract Background A methodology to assess the immune microenvironment (IME) of non‐small cell lung cancer (NSCLC) has not been established, and the prognostic impact of IME factors is not yet clear. Aims This study aimed to assess the IME factors and evaluate their prognostic values. Methods and Results We assessed CD8+ tumor‐infiltrating lymphocyte (
Yukihiro Terada, Mitsuhiro Isaka, Akira Ono, Takuya Kawata, Masakuni Serizawa, Keita Mori, Koji Muramatsu, Kiyoshi Tone, Hirotsugu Kenmotsu, Keiichi Ohshima, Kenichi Urakami, Takeshi Nagashima, Masatoshi Kusuhara, Yasuto Akiyama, Takashi Sugino, Toshiaki Takahashi, Yasuhisa Ohde   +16 more
wiley   +1 more source

Clonal forestry, heterosis and advanced-generation breeding [PDF]

, 1997
This report discusses the clonal planting stock offers many advantages to the forest products industry. Advanced-generation breeding strategies should be designed to maximize within-family variance and at the same time allow the capture of heterosis ...
Tuskan, G.A.
core  

Competition effects in a young Sitka spruce (Picea sitchensis, Bong. Carr) clonal trial [PDF]

, 2011
In the analysis of forestry experiments, there may be a need to adjust for competition between plots before predicting deployment performance in the field but there have been few attempts to investigate this.
S. Brotherstone, R. Sykes, White, I. M. S., Lee, S., Thompson, R., Connolly, T., Brotherstone, S., R. Thompson, I. M. S. White, Sykes, R., T. Connolly, S. Lee, Woolliams, J., J. Woolliams   +13 more
core   +1 more source

A multi-stage protocol for indirect somatic embryogenesis and plantlet regeneration from leaf explants of Quercus chungii

Industrial Crops and Products
Somatic embryogenesis (SE) is pivotal for mass clonal propagation in forestry, yet oak species remains recalcitrant. This study established an indirect SE protocol for Quercus chungii plantlet regeneration using leaf explants from two-year-old seedlings.
Bing-Hu Yan, Mo-Hua Yang, You Chen, Qian Li, Li-Bao Wang, Xun-Lin Yu, Tongli Wang   +6 more
doaj   +1 more source

Macropropagation of Lannea coromandelica (Houtt.) Merr. clones

Electronic Journal of Plant Breeding, 2017
The present study was undertaken to contribute to the continuous search for efficient protocol for the macropropagation of Lannea coromandelica. It investigates the main factors involved in the macropropagation process, namely cutting type, rooting ...
P. Prabakaran, S. Umesh Kanna, K.T. Parthiban, P.Rajendran and, S. Mahendran   +4 more
doaj   +1 more source

Directed evolution of enzymes at the crossroads of tradition and innovation

FEBS Open Bio, EarlyView.
An iterative cycle of data‐driven enzyme optimization comprising four stages: genetic diversification of a template enzyme, expression of protein variants, high‐throughput evaluation, and machine‐learning‐guided redesign of the next variant library.
Maria Tomkova, Andrej Mirossay, Erik Sedlak   +2 more
wiley   +1 more source

Produção e sobrevivência de miniestacas e minicepas de erva-mate cultivadas em sistema semi-hidropônico Production and survival of Ilex paraguariensis minicuttings and ministumps cultivated in semi-hydroponic system

Pesquisa Agropecuária Brasileira, 2007
O objetivo deste trabalho foi avaliar a viabilidade técnica do sistema semi-hidropônico para condução de minicepas de erva-mate e a resposta destas a soluções nutritivas de diferentes diluições nas sucessivas coletas, bem como, a sobrevivência das ...
Ivar Wendling, Leonardo Ferreira Dutra, Fernando Grossi   +2 more
doaj   +1 more source

Screening Routine Clinical Notes for Epilepsy Surgery Candidates Using Large Language Models

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Epilepsy surgery is severely underutilized despite proven efficacy, with substantial under‐referral of eligible patients in routine clinical practice. This study evaluated the potential role of large language models (LLMs) as decision‐support tools for screening unstructured clinical notes to identify epilepsy surgery candidates and ...
Uriel Fennig, Nadav Amir, Maya Schiller, Roni Loebenstein, Johnatan Nissan, Marina Boxer, Shany Guly Gofrit, Gal Goshen, Sándor Beniczky, Nicola Maggio   +9 more
wiley   +1 more source

Somatic Embryogenesis of Selected <i>Pinus</i> Species: Developmental Stages of <i>Pinus peuce</i> and <i>Pinus heldreichii</i>. [PDF]

Plants (Basel)
Somatic embryogenesis (SE) represents the most efficient and scalable technology for the mass clonal propagation and genetic improvement of superior conifer genotypes, which is crucial for meeting global wood demand and supporting forest adaptation to ...
Stojičić D, Čokeša V, Marković M, Radulović O, Uzelac B.   +4 more
europepmc   +2 more sources