Results 91 to 100 of about 84,467 (284)

Seed rain and seed persistence of Calamagrostis epigejos (l.) roth in extreme ecotoxicological conditions at an abandoned ore-washery sedimentation basin

Journal of Landscape Ecology, 2013
Clonal plants are very often among the first species to establish during primary succession. They may rapidly capture available space due to efficient vegetative propagation, but the question arises whether they may also rely on seed bank or seed rain ...
Dostál Petr, Kovář Pavel
doaj   +1 more source

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

Molecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici, Soheil Akbari, Ceyda Caliskan, Canan Celiker, Ozden Oz, Leman Binokay, Gökhan Karakulah, Serif Senturk, Esra Erdal   +8 more
wiley   +1 more source

Response of Bud Banks of a Freshwater Herbaceous Marsh Plant (Glyceria Spiculosa) to Heterogeneous Habitat: Field Observations and Experiment

Ecology and Evolution
Exploring plant adaptation strategies under habitat variations from the perspective of bud banks is essential for understanding vegetation regeneration under global changes.
Mengdie Zhou, Changwei Zhang, Xianglong Jin, Qiyao Zhang, Peng Zhang, Anni Bao, Yanjing Lou   +6 more
doaj   +1 more source

Considering Intra-individual Genetic Heterogeneity to Understand Biodiversity [PDF]

, 2019
In this chapter, I am concerned with the concept of Intra-individual Genetic Hetereogeneity (IGH) and its potential influence on biodiversity estimates. Definitions of biological individuality are often indirectly dependent on genetic sampling -and vice ...
A Cárdenas-Flores, A Roger, A Roger, AV Gonzalez, B Rinkevich, B Rinkevich, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Santelices, B Wang, C Angelard, C Wagg, DC Queller, DC Queller, DE Gill, DJ Herman, DS Wilson, E Boon, E Boon, E Boon, E Boon, E Clarke, G Kuhn, H Youssoufian, HJ Folse, HJ Folse, I Matos, I Zarraonaindia, IR Sanders, J Marleau, J Maynard Smith, J Vijg, JE Strassmann, JE Strassmann, JJ Morris, JO McInerney, JT Bonner, JT Staley, K Monro, L Collado-Vides, LW Buss, M Giovannetti, M Hijri, M O’Malley, M Pineda-Krch, M Pineda-Krch, M Schweinsberg, ME Samuels, MG Heijden van der, N Corradi, NB Spinner, P Bonfante, R Riley, RE Michod, RP Erickson, S Okasha, S Sarkar, S. Andrew Inkpen, T Fagerström, T Pradeu, T Wernberg, T Wyss, WF Doolittle, WF Doolittle   +69 more
core   +2 more sources

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Experimental field cultivation of in vitro propagated high-yield varieties of Tropaeolum majus L.

Journal of Applied Botany and Food Quality, 2012
About 10,000 mass propagated clonal progenies of the medicinal plant Tropaeolum majus L. had been cultivated in an experimental field trial to analyze the large scale cultivation of nasturtium-plants for pharmaceutical utilization.
M. Kleinwächter, I. Hutter, C. Schneider, E. Schnug, D. Selmar   +4 more
doaj  

Transient Stability of Epigenetic Population Differentiation in a Clonal Invader

Frontiers in Plant Science, 2019
Epigenetic variation may play an important role in how plants cope with novel environments. While significant epigenetic differences among plants from contrasting habitats have often been observed in the field, the stability of these differences remains ...
Wen Shi, Wen Shi, Wen Shi, Xiaojie Chen, Lexuan Gao, Cheng-Yuan Xu, Xiaokun Ou, Oliver Bossdorf, Ji Yang, Yupeng Geng   +9 more
doaj   +1 more source

Maintenance of Clonal Plant Germplasm

HortScience, 1982
Abstract Rubus parviflorus Nutt., the thimbleberry, shown in bloom on the cover, is a common native of the Pacific Coast region of North America. It and an associated species, R. spectabilis Pursh, the salmonberry, have a raspberry-type fruit. The R. parviflorus fruit has many small drupelets and is a dark-red color, while R.
openaire   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

Molecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker, Keren Zohar, Martin Böttcher, Thomas Wartmann, Henry Freudenstein, Maximilian Doelling, Mihailo Andric, Wenjie Shi, Or Kakhlon, Katrin Hippe, Beatrix Jahnke, Dimitrios Mougiakakos, Franziska Baenke, Daniel Stange, Roland S. Croner, Michal Linial, Ulf D. Kahlert   +16 more
wiley   +1 more source