<p>Genetic dataset associated to "High clonal propagation and low population connectivity in the holothurian <em>Stichopus chloronotus</em> from the Indo-Pacific" article published in Marine Biology (2019)</p ...
Hélène MAGALON (8283843) +11 more
core +1 more source
Molecular Dissection of the Regenerative Capacity of Forest Tree Species: Special Focus on Conifers
Somatic embryogenesis (SE) and organogenesis have become leading biotechnologies for forest tree improvement and the implementation of multi-varietal forestry.
Carmen Díaz-Sala
doaj +1 more source
Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima +7 more
wiley +1 more source
MARK4 enhances stress granule formation under oxidative stress and increases tau accumulation
MARK4 (red dots) localizes to stress granules (orange dots) and promotes their formation under oxidative stress by modulating TIA1 (blue dots). MARK4 and TIA1 synergistically increase tau (purple) accumulation, and the reduction of the TIA1 ortholog suppresses neurodegeneration in a fly model.
Sho Nakajima +8 more
wiley +1 more source
IGF2 knockout reduces but does not abolish osteosarcoma growth in vitro and in vivo
To test whether endogenous IGF2 promotes osteosarcoma growth, IGF2 was knocked out in Saos2 cells via CRISPR‐Cas9. KO cells showed reduced proliferation in vitro, and knockout xenografts in mice reached only ~25% of wild‐type tumor volume. Insulin‐like growth factor 2 (IGF2) is implicated in osteosarcoma, but direct functional evidence of its role is ...
Shun Yao, Marco Archetti
wiley +1 more source
Temperature and inoculation method influence disease phenotypes and mortality of Eucalyptus marginata clonal lines inoculated with Phytophthora cinnamomi [PDF]
Survival of 1-year-old plants of three clonal lines of Eucalyptus marginata (jarrah), two ranked as resistant (RR1 and RR2) and one as susceptible (SS1) to Phytophthora cinnamomi, was assessed after pathogen inoculation with either mycelial mats ...
Calver, M.C. +4 more
core
siddhartha-kar/clonal-hematopoiesis: clonal hematopoiesis paper code repository
This is the repository accompanying the pre-print titled, "Genome-wide analyses of 200,453 individuals yields new insights into the causes and consequences of clonal hematopoiesis" (https://www.medrxiv.org/content/10.1101/2022.01.06.22268846v1)
Siddhartha Kar
core +1 more source
Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley +1 more source
In vitro Mass Clonal Propagation of Spathoglottis plicata Blume
For in vitro clonal propagation of Spathoglottis plicata Blume nodal segments of young shoots were cultured on half strength of MS with 2% sucrose + 2.0 mg/l BA + 0.5 mg/l NAA + 2 g/l peptone + 15% (v/v) CW + 0.5 g/l AC, incubated at 24 ± 2ºC under ...
M. Firoz Alam +2 more
core +1 more source
Clonal propagation of Detarium microcarpum from root cuttings
Detarium microcarpum is a valuable tree species for fuelwood, timber, food and medicine in sub-Saharan Africa. However, its population is dwindling due to overexploitation, its seedlingsâ low survival rate and slow growth.
Ky-Dembele, Catherine +5 more
doaj +1 more source

